Rxivist logo

Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 63,016 bioRxiv papers from 279,490 authors.

Author: Alexander Gusev

  • Most recently observed institution: Dana-Farber Cancer Institute

Rankings

  • All-time downloads: 63,369 (rank: 188 out of 279,490)
  • Categories:
    • cancer biology: 493 (rank: 6,344 (tie) out of 17,295)
    • epidemiology: 1,193 (rank: 745 (tie) out of 9,536)
    • evolutionary biology: 1,276 (rank: 2,260 (tie) out of 15,284)
    • genetics: 41,035 (rank: 80 out of 27,813)
    • genomics: 19,372 (rank: 337 out of 31,998)

Downloads per author, site-wide

Preprints

An Atlas of Genetic Correlations across Human Diseases and Traits

genomics more details view paper
  • Downloaded 12,875 times
  • Download rankings, all-time:
    • Site-wide: 65 out of 63,016
    • In genomics: 19 out of 4,328
  • Year to date:
    • Site-wide: 2,792 out of 63,016
  • Since beginning of last month:
    • Site-wide: 6,370 out of 63,016

Partitioning heritability by functional category using GWAS summary statistics

genetics more details view paper
  • Downloaded 6,730 times
  • Download rankings, all-time:
    • Site-wide: 240 out of 63,016
    • In genetics: 26 out of 3,574
  • Year to date:
    • Site-wide: 2,269 out of 63,016
  • Since beginning of last month:
    • Site-wide: 4,883 out of 63,016

Regulatory variants explain much more heritability than coding variants across 11 common diseases

genetics more details view paper
  • Downloaded 4,253 times
  • Download rankings, all-time:
    • Site-wide: 557 out of 63,016
    • In genetics: 60 out of 3,574
  • Year to date:
    • Site-wide: 26,076 out of 63,016
  • Since beginning of last month:
    • Site-wide: 23,400 out of 63,016

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

genetics more details view paper
  • Downloaded 3,807 times
  • Download rankings, all-time:
    • Site-wide: 696 out of 63,016
    • In genetics: 68 out of 3,574
  • Year to date:
    • Site-wide: 9,720 out of 63,016
  • Since beginning of last month:
    • Site-wide: 12,296 out of 63,016

Contrasting regional architectures of schizophrenia and other complex diseases using fast variance components analysis

genetics more details view paper
  • Downloaded 2,942 times
  • Download rankings, all-time:
    • Site-wide: 1,126 out of 63,016
    • In genetics: 104 out of 3,574
  • Year to date:
    • Site-wide: 36,511 out of 63,016
  • Since beginning of last month:
    • Site-wide: 40,895 out of 63,016

Haplotypes of common SNPs can explain missing heritability of complex diseases

genetics more details view paper
  • Downloaded 2,907 times
  • Download rankings, all-time:
    • Site-wide: 1,152 out of 63,016
    • In genetics: 106 out of 3,574
  • Year to date:
    • Site-wide: 36,133 out of 63,016
  • Since beginning of last month:
    • Site-wide: 34,585 out of 63,016

Tumor mutational landscape is a record of the pre-malignant state

genomics more details view paper
  • Downloaded 2,648 times
  • Download rankings, all-time:
    • Site-wide: 1,356 out of 63,016
    • In genomics: 314 out of 4,328
  • Year to date:
    • Site-wide: 228 out of 63,016
  • Since beginning of last month:
    • Site-wide: 5,755 out of 63,016

Integrative approaches for large-scale transcriptome-wide association studies

genetics more details view paper
  • Downloaded 2,617 times
  • Download rankings, all-time:
    • Site-wide: 1,378 out of 63,016
    • In genetics: 134 out of 3,574
  • Year to date:
    • Site-wide: 20,354 out of 63,016
  • Since beginning of last month:
    • Site-wide: 25,411 out of 63,016

Linkage disequilibrium dependent architecture of human complex traits reveals action of negative selection

genetics more details view paper
  • Downloaded 2,536 times
  • Download rankings, all-time:
    • Site-wide: 1,449 out of 63,016
    • In genetics: 140 out of 3,574
  • Year to date:
    • Site-wide: 22,442 out of 63,016
  • Since beginning of last month:
    • Site-wide: 24,729 out of 63,016

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

genomics more details view paper
  • Downloaded 2,397 times
  • Download rankings, all-time:
    • Site-wide: 1,625 out of 63,016
    • In genomics: 362 out of 4,328
  • Year to date:
    • Site-wide: 20,144 out of 63,016
  • Since beginning of last month:
    • Site-wide: 22,486 out of 63,016

Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk

genetics more details view paper
  • Downloaded 2,275 times
  • Download rankings, all-time:
    • Site-wide: 1,766 out of 63,016
    • In genetics: 166 out of 3,574
  • Year to date:
    • Site-wide: 17,209 out of 63,016
  • Since beginning of last month:
    • Site-wide: 22,521 out of 63,016

Estimating the proportion of disease heritability mediated by gene expression levels

genetics more details view paper
  • Downloaded 2,006 times
  • Download rankings, all-time:
    • Site-wide: 2,235 out of 63,016
    • In genetics: 214 out of 3,574
  • Year to date:
    • Site-wide: 14,974 out of 63,016
  • Since beginning of last month:
    • Site-wide: 16,752 out of 63,016

Integrating gene expression with summary association statistics to identify susceptibility genes for 30 complex traits

genetics more details view paper
  • Downloaded 1,729 times
  • Download rankings, all-time:
    • Site-wide: 2,878 out of 63,016
    • In genetics: 257 out of 3,574
  • Year to date:
    • Site-wide: 25,996 out of 63,016
  • Since beginning of last month:
    • Site-wide: 21,932 out of 63,016

Leveraging molecular QTL to understand the genetic architecture of diseases and complex traits

genetics more details view paper
  • Downloaded 1,506 times
  • Download rankings, all-time:
    • Site-wide: 3,613 out of 63,016
    • In genetics: 318 out of 3,574
  • Year to date:
    • Site-wide: 23,498 out of 63,016
  • Since beginning of last month:
    • Site-wide: 25,835 out of 63,016

Probabilistic fine-mapping of transcriptome-wide association studies

genetics more details view paper
  • Downloaded 1,494 times
  • Download rankings, all-time:
    • Site-wide: 3,666 out of 63,016
    • In genetics: 322 out of 3,574
  • Year to date:
    • Site-wide: 3,894 out of 63,016
  • Since beginning of last month:
    • Site-wide: 9,297 out of 63,016

Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

genetics more details view paper
  • Downloaded 1,324 times
  • Download rankings, all-time:
    • Site-wide: 4,477 out of 63,016
    • In genetics: 374 out of 3,574
  • Year to date:
    • Site-wide: 54,551 out of 63,016
  • Since beginning of last month:
    • Site-wide: 57,908 out of 63,016

An evolutionary compass for detecting signals of polygenic selection and mutational bias

evolutionary biology more details view paper
  • Downloaded 1,276 times
  • Download rankings, all-time:
    • Site-wide: 4,749 out of 63,016
    • In evolutionary biology: 257 out of 4,239
  • Year to date:
    • Site-wide: 24,553 out of 63,016
  • Since beginning of last month:
    • Site-wide: 28,116 out of 63,016

Transcriptome-wide association studies accounting for colocalization using Egger regression

epidemiology more details view paper
  • Downloaded 1,193 times
  • Download rankings, all-time:
    • Site-wide: 5,287 out of 63,016
    • In epidemiology: 50 out of 1,556
  • Year to date:
    • Site-wide: 32,451 out of 63,016
  • Since beginning of last month:
    • Site-wide: 23,715 out of 63,016

Subtle stratification confounds estimates of heritability from rare variants

genetics more details view paper
  • Downloaded 950 times
  • Download rankings, all-time:
    • Site-wide: 7,673 out of 63,016
    • In genetics: 595 out of 3,574
  • Year to date:
    • Site-wide: 37,098 out of 63,016
  • Since beginning of last month:
    • Site-wide: 27,066 out of 63,016

Correcting subtle stratification in summary association statistics

genetics more details view paper
  • Downloaded 770 times
  • Download rankings, all-time:
    • Site-wide: 10,642 out of 63,016
    • In genetics: 765 out of 3,574
  • Year to date:
    • Site-wide: 31,112 out of 63,016
  • Since beginning of last month:
    • Site-wide: 30,131 out of 63,016

Functional partitioning of local and distal gene expression regulation in multiple human tissues

genomics more details view paper
  • Downloaded 768 times
  • Download rankings, all-time:
    • Site-wide: 10,675 out of 63,016
    • In genomics: 1,529 out of 4,328
  • Year to date:
    • Site-wide: 57,504 out of 63,016
  • Since beginning of last month:
    • Site-wide: 61,291 out of 63,016

Multi-Tissue Transcriptome-Wide Association Studies Identify 21 Novel Candidate Susceptibility Genes for High Grade Serous Epithelial Ovarian Cancer

genomics more details view paper
  • Downloaded 684 times
  • Download rankings, all-time:
    • Site-wide: 12,626 out of 63,016
    • In genomics: 1,736 out of 4,328
  • Year to date:
    • Site-wide: 12,840 out of 63,016
  • Since beginning of last month:
    • Site-wide: 24,834 out of 63,016

Leveraging distant relatedness to quantify human mutation and gene conversion rates

genetics more details view paper
  • Downloaded 660 times
  • Download rankings, all-time:
    • Site-wide: 13,272 out of 63,016
    • In genetics: 939 out of 3,574
  • Year to date:
    • Site-wide: 56,986 out of 63,016
  • Since beginning of last month:
    • Site-wide: 60,062 out of 63,016

Germline features associated with immune infiltration in solid tumors

genetics more details view paper
  • Downloaded 616 times
  • Download rankings, all-time:
    • Site-wide: 14,584 out of 63,016
    • In genetics: 1,017 out of 3,574
  • Year to date:
    • Site-wide: 3,463 out of 63,016
  • Since beginning of last month:
    • Site-wide: 11,882 out of 63,016

Non-coding Somatic Mutations Converge on the PAX8 Pathway in Epithelial Ovarian Cancer

cancer biology more details view paper
  • Downloaded 493 times
  • Download rankings, all-time:
    • Site-wide: 19,605 out of 63,016
    • In cancer biology: 590 out of 2,072
  • Year to date:
    • Site-wide: 5,053 out of 63,016
  • Since beginning of last month:
    • Site-wide: 9,740 out of 63,016

Quantifying genetic effects on disease mediated by assayed gene expression levels

genetics more details view paper
  • Downloaded 491 times
  • Download rankings, all-time:
    • Site-wide: 19,691 out of 63,016
    • In genetics: 1,324 out of 3,574
  • Year to date:
    • Site-wide: 5,090 out of 63,016
  • Since beginning of last month:
    • Site-wide: 2,246 out of 63,016

Mixed Model Association with Family-Biased Case-Control Ascertainment

genetics more details view paper
  • Downloaded 413 times
  • Download rankings, all-time:
    • Site-wide: 23,995 out of 63,016
    • In genetics: 1,586 out of 3,574
  • Year to date:
    • Site-wide: 53,627 out of 63,016
  • Since beginning of last month:
    • Site-wide: 58,822 out of 63,016

Annotations capturing cell-type-specific TF binding explain a large fraction of disease heritability

genetics more details view paper
  • Downloaded 399 times
  • Download rankings, all-time:
    • Site-wide: 24,935 out of 63,016
    • In genetics: 1,632 out of 3,574
  • Year to date:
    • Site-wide: 22,621 out of 63,016
  • Since beginning of last month:
    • Site-wide: 42,500 out of 63,016

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

genetics more details view paper
  • Downloaded 393 times
  • Download rankings, all-time:
    • Site-wide: 25,391 out of 63,016
    • In genetics: 1,662 out of 3,574
  • Year to date:
    • Site-wide: 42,054 out of 63,016
  • Since beginning of last month:
    • Site-wide: 36,937 out of 63,016

Allelic imbalance reveals widespread germline-somatic regulatory differences and prioritizes risk loci in Renal Cell Carcinoma

genetics more details view paper
  • Downloaded 217 times
  • Download rankings, all-time:
    • Site-wide: 42,033 out of 63,016
    • In genetics: 2,548 out of 3,574
  • Year to date:
    • Site-wide: 18,079 out of 63,016
  • Since beginning of last month:
    • Site-wide: 12,994 out of 63,016

Sign up for the Rxivist weekly newsletter! (Click here for more details.)


News