Author: Erik Ingelsson

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Preprints

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

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Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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Large-scale non-targeted metabolomic profiling in three human population-based studies

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Identification of rare-disease genes in diverse undiagnosed cases using whole blood transcriptome sequencing and large control cohorts

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Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight novel adipocyte biology

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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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Genetic analyses in UK Biobank identifies 78 novel loci associated with urinary biomarkers providing new insights into the biology of kidney function and chronic disease

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Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

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Large-scale phenome-wide association study of PCSK9 loss-of-function variants demonstrates protection against ischemic stroke

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Fitness, Physical Activity, And Cardiovascular Disease: Longitudinal And Genetic Analyses In The UK Biobank Study

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Zebrafish larvae as a model system for systematic characterization of drugs and genes in dyslipidemia and atherosclerosis

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Genetic dysregulation of gene expression and splicing during a ten-year period of human aging

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Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

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Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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Birthweight, Type 2 Diabetes and Cardiovascular Disease: Addressing the Barker Hypothesis with Mendelian randomization

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Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

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Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank

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Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

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Bioimpedance and new onset heart failure: A longitudinal study of ~500,000 individuals from the general population

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Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR-Cas9-based approach

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Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

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Genetic regulatory mechanisms of smooth muscle cells map to coronary artery disease risk loci

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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

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Meta-analysis of exome array data identifies six novel genetic loci for lung function

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Loss of function, missense, and intronic variants in NOTCH1 confer different risks for left ventricular outflow tract obstructive heart defects in two European cohorts

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Urinary biomarkers and cardiovascular outcomes in the UK Biobank: observational and Mendelian randomization analyses

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Development and validation of a next-gen health stratification engine to determine risk for multiple cardiovascular diseases

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Prediction performance of a cardiovascular risk assessment tool using Stanford EHR data repository

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