Author: Francesca Luca

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Preprints

Gut microbiota has a widespread and modifiable effect on host gene regulation

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Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells

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  • Site-wide: 10,294
  • In genomics: 1,144
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Which genetic variants in DNase I sensitive regions are functional?

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  • In genomics: 1,208
• Year to date:
  • Site-wide: 104,357
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QuASAR: Quantitative Allele Specific Analysis of Reads

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  • Site-wide: 12,215
  • In bioinformatics: 1,508
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  • Site-wide: 49,729
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  • Site-wide: 80,544

Does the human placenta express the canonical cell entry mediators for SARS-CoV-2?

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  • Site-wide: 13,297
  • In genomics: 1,447
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Cross-population Joint Analysis of eQTLs: Fine Mapping and Functional Annotation

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  • Site-wide: 14,436
  • In genetics: 740
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  • Site-wide: 83,325
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High throughput characterization of genetic effects on DNA:protein binding and gene transcription

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  • Site-wide: 16,122
  • In genetics: 816
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QuASAR-MPRA: Accurate allele-specific analysis for massively parallel reporter assays

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  • Site-wide: 18,813
  • In bioinformatics: 2,270
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  • Site-wide: 78,946

Efficient Integrative Multi-SNP Association Analysis using Deterministic Approximation of Posteriors

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  • Site-wide: 19,342
  • In genetics: 962
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Investigating tissue-relevant causal molecular mechanisms of complex traits using probabilistic TWAS analysis

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  • In genetics: 1,183
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  • Site-wide: 36,481
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  • Site-wide: 41,363

Single Cell Transcriptional Signatures of the Human Placenta in Term and Preterm Parturition

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  • In genomics: 2,463
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Genetic and transcriptional analysis of human host response to healthy gut microbiome

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  • Site-wide: 30,859
  • In genomics: 2,799
• Year to date:
  • Site-wide: 104,219
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  • Site-wide: 78,441

Integrating Molecular QTL Data into Genome-wide Genetic Association Analysis: Probabilistic Assessment of Enrichment and Colocalization

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  • Site-wide: 35,031
  • In genetics: 1,715
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  • Site-wide: 49,877
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  • Site-wide: 52,362

Interpreting coronary artery disease risk through gene-environment interactions in gene regulation

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  • Site-wide: 35,808
  • In genomics: 3,121
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  • Site-wide: 55,514
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  • Site-wide: 41,628

circuitSNPs: Predicting genetic effects using a Neural Network to model regulatory modules of DNase-seq footprints

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  • Site-wide: 45,867
  • In bioinformatics: 4,851
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  • Site-wide: 96,623
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Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions

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  • Site-wide: 54,104
  • In genomics: 4,167
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  • Site-wide: 446

Probabilistic Colocalization of Genetic Variants from Complex and Molecular Traits: Promise and Limitations

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  • Site-wide: 58,419
  • In genetics: 2,764
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  • Site-wide: 19,664
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  • Site-wide: 23,128

Interspecies variation in hominid gut microbiota controls host gene regulation

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  • Site-wide: 61,668
  • In genomics: 4,512
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  • Site-wide: 18,156
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  • Site-wide: 15,085

BAGSE: a Bayesian hierarchical model approach for gene set enrichment analysis

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  • Site-wide: 63,632
  • In bioinformatics: 6,232
• Year to date:
  • Site-wide: 104,555
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  • Site-wide: 77,029

Psychosocial experiences modulate asthma-associated genes through gene-environment interactions

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  • Site-wide: 85,861
  • In genomics: 5,478
• Year to date:
  • Site-wide: 41,016
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  • Site-wide: 33,396