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Author: William J. Greenleaf

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  • All-time downloads: 74,913 (rank: 499 out of 384,482)
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    • biochemistry: 2,645 (rank: 568 out of 17,768)
    • bioinformatics: 6,551 (rank: 1,164 out of 32,905)
    • biophysics: 2,744 (rank: 657 out of 15,925)
    • developmental biology: 2,710 (rank: 474 (tie) out of 14,903)
    • genetics: 624 (rank: 18,144 (tie) out of 35,526)
    • genomics: 52,749 (rank: 121 out of 40,907)
    • molecular biology: 4,030 (rank: 464 out of 20,002)
    • neuroscience: 2,317 (rank: 6,506 (tie) out of 64,424)
    • synthetic biology: 543 (rank: 2,363 (tie) out of 3,940)

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Preprints

Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion

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Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation

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Coupled single-cell CRISPR screening and epigenomic profiling reveals causal gene regulatory networks

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An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

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Single-cell epigenomic identification of inherited risk loci in Alzheimer's and Parkinson's disease

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Landscape of stimulation-responsive chromatin across diverse human immune cells

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Unsupervised clustering and epigenetic classification of single cells

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High-throughput chromatin accessibility profiling at single-cell resolution

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Large-scale, quantitative protein assays on a high-throughput DNA sequencing chip

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Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans

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ArchR: An integrative and scalable software package for single-cell chromatin accessibility analysis

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chromVAR: Inferring transcription factor variation from single-cell epigenomic data

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HiChIP: Efficient and sensitive analysis of protein-directed genome architecture

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Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

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Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity

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Single-cell transcriptomic analysis of the adult mouse spinal cord

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Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements

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High-throughput biochemical profiling reveals Cas9 off-target binding and unbinding heterogeneity

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High-resolution mapping of cancer cell networks using co-functional interactions

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High-Resolution Dissection of Conducive Reprogramming Trajectory to Ground State Pluripotency

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Prospects for recurrent neural network models to learn RNA biophysics from high-throughput data

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Neutralizing Gatad2a-Chd4-Mbd3 Axis within the NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

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A quantitative and predictive model for RNA binding by human Pumilio proteins

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RNA tertiary structure energetics predicted by an ensemble model of the RNA double helix

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Satb1 integrates DNA sequence, shape, motif density and torsional stress to differentially bind targets in nucleosome-dense regions.

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Quantitative high-throughput tests of ubiquitous RNA secondary structure prediction algorithms via RNA/protein binding

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Cell cycle dynamics of human pluripotent stem cells primed for differentiation

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Crowdsourced RNA design discovers diverse, reversible, efficient, self-contained molecular sensors

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Nonparametric analysis of contributions to variance in genomics and epigenomics data

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INO80 Chromatin Remodelling Coordinates Metabolic Homeostasis with Cell Division

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