Author: James J. Lah

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Preprints

A Consensus Proteomic Analysis of Alzheimer’s Disease Brain and Cerebrospinal Fluid Reveals Early Changes in Energy Metabolism Associated with Microglia and Astrocyte Activation

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Multiscale causal network models of Alzheimer's disease identify VGF as a key regulator of disease

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Integrated Proteomics Reveals Brain-Based Cerebrospinal Fluid Biomarkers in Asymptomatic and Symptomatic Alzheimer’s Disease

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Genetic control of the human brain proteome

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RNA-binding proteins with mixed charge domains self-assemble and aggregate in Alzheimer's Disease

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Tau-mediated Disruption of the Spliceosome Triggers Cryptic RNA-splicing and Neurodegeneration in Alzheimer's Disease

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Identification of conserved proteomic networks in neurodegenerative dementia

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Microglial ERK signaling is a critical regulator of pro-inflammatory immune responses in Alzheimer’s disease

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Large-scale proteomic analysis of human prefrontal cortex identifies proteins associated with cognitive trajectory in advanced age

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Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease

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Cerebral atherosclerosis contributes to Alzheimer's dementia independently of its hallmark amyloid and tau pathologies

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Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia

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TBK1 interacts with tau and enhances neurodegeneration in tauopathy

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Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease

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