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Author: Patrick R Griffin

Rankings

  • All-time downloads: 8,676 (rank: 19,709 (tie) )
  • Categories:
    • biochemistry: 5,079 (rank: 336 )
    • biophysics: 1,764 (rank: 1,988 )
    • cancer biology: 796 (rank: 8,957 (tie) )
    • cell biology: 248 (rank: 27,323 (tie) )
    • molecular biology: 561 (rank: 9,549 (tie) )
    • pharmacology and toxicology: 81 (rank: 6,759 (tie) )
    • physiology: 147 (rank: 8,546 (tie) )

Downloads per author, site-wide

Preprints

Structural basis for the RNA-guided ribonuclease activity of CRISPR-Cas13d

biochemistry more details view paper
  • Downloaded 4,273 times
  • Download rankings, all-time:
    • Site-wide: 2,160
    • In biochemistry: 34
  • Year to date:
    • Site-wide: 22,213
  • Since beginning of last month:
    • Site-wide: 8,260

Defining a canonical ligand-binding pocket in the orphan nuclear receptor Nurr1

biophysics more details view paper
  • Downloaded 1,083 times
  • Download rankings, all-time:
    • Site-wide: 16,459
    • In biophysics: 425
  • Year to date:
    • Site-wide: 37,840
  • Since beginning of last month:
    • Site-wide: 47,934

The SERM/SERD Bazedoxifene Disrupts ESR1 Helix 12 to Overcome Acquired Hormone Resistance in Breast Cancer Cells

cancer biology more details view paper
  • Downloaded 572 times
  • Download rankings, all-time:
    • Site-wide: 39,898
    • In cancer biology: 1,096
  • Year to date:
    • Site-wide: 72,034
  • Since beginning of last month:
    • Site-wide: 60,334

Structures of the Human LONP1 Protease Reveal Regulatory Steps Involved in Protease Activation

molecular biology more details view paper
  • Downloaded 561 times
  • Download rankings, all-time:
    • Site-wide: 40,889
    • In molecular biology: 1,176
  • Year to date:
    • Site-wide: 9,572
  • Since beginning of last month:
    • Site-wide: 4,003

Structural basis of altered potency and efficacy displayed by a major in vivo metabolite of the anti-diabetic PPARγ drug pioglitazone

biochemistry more details view paper
  • Downloaded 436 times
  • Download rankings, all-time:
    • Site-wide: 54,837
    • In biochemistry: 1,452
  • Year to date:
    • Site-wide: 88,173
  • Since beginning of last month:
    • Site-wide: 94,337

Quantitative Structural Assessment of Graded Receptor Agonism

biophysics more details view paper
  • Downloaded 376 times
  • Download rankings, all-time:
    • Site-wide: 63,424
    • In biophysics: 2,315
  • Year to date:
    • Site-wide: 65,044
  • Since beginning of last month:
    • Site-wide: 89,871

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calmodulin (CaM) Effector in Mouse Brain

biochemistry more details view paper
  • Downloaded 370 times
  • Download rankings, all-time:
    • Site-wide: 64,474
    • In biochemistry: 1,748
  • Year to date:
    • Site-wide: 113,883
  • Since beginning of last month:
    • Site-wide: 89,281

HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists

biophysics more details view paper
  • Downloaded 305 times
  • Download rankings, all-time:
    • Site-wide: 75,676
    • In biophysics: 2,877
  • Year to date:
    • Site-wide: 105,306
  • Since beginning of last month:
    • Site-wide: 85,045

A Simple and Robust Cell Based Assay for the Discovery of Novel Cytokinesis Inhibitors

cell biology more details view paper
  • Downloaded 248 times
  • Download rankings, all-time:
    • Site-wide: 87,371
    • In cell biology: 4,076
  • Year to date:
    • Site-wide: 91,740
  • Since beginning of last month:
    • Site-wide: 97,579

Dual-mechanism estrogen receptor inhibitors expand the repertoire of anti-hormone therapy for breast cancer

cancer biology more details view paper
  • Downloaded 224 times
  • Download rankings, all-time:
    • Site-wide: 92,384
    • In cancer biology: 2,802
  • Year to date:
    • Site-wide: 46,896
  • Since beginning of last month:
    • Site-wide: 29,969

PPARG in osteocytes is essential for sclerostin expression, bone mass, marrow adiposity and TZD-induced bone loss

physiology more details view paper
  • Downloaded 147 times
  • Download rankings, all-time:
    • Site-wide: 107,794
    • In physiology: 1,206
  • Year to date:
    • Site-wide: 61,256
  • Since beginning of last month:
    • Site-wide: 41,402

Discovery of a Novel, Selective and Short-Acting Skeletal Myosin II Inhibitor

pharmacology and toxicology more details view paper
  • Downloaded 81 times
  • Download rankings, all-time:
    • Site-wide: 119,148
    • In pharmacology and toxicology: 1,014
  • Year to date:
    • Site-wide: 86,496
  • Since beginning of last month:
    • Site-wide: 103,325

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