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Author: Yukinori Okada

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  • All-time downloads: 24,586 (rank: 1,813 out of 362,987)
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    • genetics: 24,586 (rank: 210 out of 34,016)

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Preprints

Tractor: A framework allowing for improved inclusion of admixed individuals in large-scale association studies.

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Partitioning heritability by functional category using GWAS summary statistics

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Current clinical use of polygenic scores will risk exacerbating health disparities

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Genetic analyses identify widespread sex-differential participation bias

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Identification of type 2 diabetes loci in 433,540 East Asian individuals

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Large scale genome-wide association study in a Japanese population identified 45 novel susceptibility loci for 22 diseases

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Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

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IMPACT: Genomic annotation of cell-state-specific regulatory elements inferred from the epigenome of bound transcription factors

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Population-specific causal disease effect sizes in functionally important regions impacted by selection

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Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan

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Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

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The association between the HLA-DRB1 shared epitope alleles and the risk of rheumatoid arthritis is influenced by massive gene-gene interactions.

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Evidence of polygenic adaptation at height-associated loci in mainland Europeans and Sardinians

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Genome-wide association meta-analysis identifies novel GP2 gene risk variants for pancreatic cancer in the Japanese population

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Mechanistic characterization of RASGRP1 variants identifies an hnRNP K-regulated transcriptional enhancer contributing to SLE susceptibility

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Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control.

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Structural basis of ethnic-specific variants of PAX4 associated with type 2 diabetes

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