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Author: 23andMe Research Team

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  • All-time downloads: 39,836 (rank: 882 out of 363,914)
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    • genetics: 27,550 (rank: 181 out of 34,066)
    • genomics: 11,844 (rank: 1,034 out of 39,231)
    • neuroscience: 442 (rank: 32,090 (tie) out of 61,224)

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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MTAG: Multi-Trait Analysis of GWAS

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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

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Genetic Identification of Cell Types Underlying Brain Complex Traits Yields Novel Insights Into the Etiology of Parkinson’s Disease

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LDpred-funct: incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets

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Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations

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Genetic predisposition to mosaic Y chromosome loss in blood is associated with genomic instability in other tissues and susceptibility to non-haematological cancers

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Characterization of prevalence and health consequences of uniparental disomy in four million individuals from the general population

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Large-Scale Genome-Wide Meta Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria.

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Genetic predisposition to myeloproliferative neoplasms implicates hematopoietic stem cell biology

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Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

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Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

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A two-stage approach to identifying and validating modifiable factors for the prevention of depression

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Accelerated Epigenetic Ageing in Major Depressive Disorder

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A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma and includes a genetic link with Alzheimer's disease

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The Parkinsons Disease Mendelian Randomization Research Portal

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Insight into the genetic aetiology of retinal detachment by combining small clinical and large population-based datasets

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Expanded genomic analyses for male voice-breaking highlights a shared phenotypic and genetic basis between puberty timing and hair colour

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Common variant burden contributes significantly to the familial aggregation of migraine in 1,589 families

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Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

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Overlapping Genetic Architecture between Parkinson Disease and Melanoma

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Association of whole-genome and NETRIN1 signaling pathway-derived polygenic risk scores for Major Depressive Disorder and thalamic radiation white matter microstructure in UK Biobank

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Fine-mapping of SNCA in REM sleep behavior disorder and overt synucleinopathies

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Genome-wide association analysis and replication in 810,625 individuals identifies novel therapeutic targets for varicose veins

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Genome-wide association study of pain sensitivity assessed by questionnaire and the cold pressor test

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