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Author: Naomi R Wray

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  • All-time downloads: 99,566 (rank: 349 out of 428,374)
  • Categories:
    • bioinformatics: 3,733 (rank: 2,888 (tie) out of 36,286)
    • epidemiology: 269 (rank: 7,068 (tie) out of 9,545)
    • genetics: 76,796 (rank: 36 out of 38,055)
    • genomics: 17,663 (rank: 553 out of 44,710)
    • neuroscience: 1,105 (rank: 16,994 (tie) out of 72,455)

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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Genetic Consequences of Social Stratification in Great Britain

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Genomewide association study identifies 30 loci associated with bipolar disorder

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New mutations, old statistical challenges

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Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

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Regulatory variants explain much more heritability than coding variants across 11 common diseases

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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

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Contrasting regional architectures of schizophrenia and other complex diseases using fast variance components analysis

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Haplotypes of common SNPs can explain missing heritability of complex diseases

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Commentary on "Limitations of GCTA as a solution to the missing heritability problem"

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Improved polygenic prediction by Bayesian multiple regression on summary statistics

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A comparative study of techniques for differential expression analysis on RNA-Seq data

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A resource-efficient tool for mixed model association analysis of large-scale data

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Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

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GWAS on family history of Alzheimer's disease

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Causal associations between risk factors and common diseases inferred from GWAS summary data

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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

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A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

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Bayesian reassessment of the epigenetic architecture of complex traits

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Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

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Imprint of Assortative Mating on the Human Genome

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Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

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Bayesian analysis of GWAS summary data reveals differential signatures of natural selection across human complex traits and functional genomic categories

genetics more details view paper
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Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

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Estimation of genetic correlation using linkage disequilibrium score regression and genomic restricted maximum likelihood

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Using genotype data to distinguish pleiotropy from heterogeneity: deciphering coheritability in autoimmune and neuropsychiatric diseases

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Identification of 55,000 Replicated DNA Methylation QTL

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Epigenetic prediction of complex traits and death

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GWAS of epigenetic ageing rates in blood reveals a critical role for TERT

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Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

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Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

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Widespread associations between grey matter structure and the human phenome

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Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration.

genetics more details view paper
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Genetic Association Study of Childhood Aggression across raters, instruments and age

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Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

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Genotype-covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model

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Cross-disorder GWAS meta-analysis for Attention Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, Obsessive Compulsive Disorder, and Tourette Syndrome

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The Australian Genetics of Depression Study: Study Description and Sample Characteristics

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Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data

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Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

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Genome-wide association study of gastrointestinal disorders reinforces the link between the digestive tract and the nervous system

genomics more details view paper
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Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

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Exploring contributors to variability in estimates of SNP-heritability and genetic correlations from the iPSYCH case-cohort and published meta-studies of major psychiatric disorders.

genetics more details view paper
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Genetic analyses of medication-use and implications for precision medicine

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Age at first birth in women is genetically associated with increased risk of schizophrenia

genetics more details view paper
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A better design for stratified medicine based on genomic prediction

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Integrative omics approach to identify the molecular architecture of inflammatory protein levels in healthy older adults

genomics more details view paper
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Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

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Rare Genetic Variants Underlie Outlying levels of DNA Methylation and Gene-Expression

genetics more details view paper
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Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing

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