Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 64,929 bioRxiv papers from 287,755 authors.

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Preprints

Genetic Consequences of Social Stratification in Great Britain

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Meta-analysis of genome-wide association studies for height and body mass index in ~700,000 individuals of European ancestry

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  • In genetics: 42 out of 3,683
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Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

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Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease

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Investigating causal relationships between sleep traits and risk of breast cancer: a Mendelian randomization study

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Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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  • In genetics: 275 out of 3,683
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Genome-wide association analyses in >119,000 individuals identifies thirteen morningness and two sleep duration loci

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  • In genetics: 335 out of 3,683
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Assessing the pathogenicity, penetrance and expressivity of putative disease-causing variants in a population setting

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Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

• Downloaded 1,248 times
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  • In genetics: 413 out of 3,683
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  • Site-wide: 9,348 out of 64,934
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  • Site-wide: 8,808 out of 64,934

GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

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  • In genetics: 429 out of 3,683
• Year to date:
  • Site-wide: 6,526 out of 64,934
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  • Site-wide: 6,740 out of 64,934

Biological and clinical insights from genetics of insomnia symptoms

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  • In genomics: 926 out of 4,441
• Year to date:
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  • Site-wide: 26,016 out of 64,934

Mosaic Turner syndrome shows reduced phenotypic penetrance in an adult population study compared to clinically ascertained cases

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  • In genetics: 451 out of 3,683
• Year to date:
  • Site-wide: 6,235 out of 64,934
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  • Site-wide: 6,997 out of 64,934

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • In genetics: 467 out of 3,683
• Year to date:
  • Site-wide: 3,400 out of 64,934
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  • Site-wide: 7,821 out of 64,934

HUMAN LONGEVITY IS INFLUENCED BY MANY GENETIC VARIANTS: EVIDENCE FROM 75,000 UK BIOBANK PARTICIPANTS

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  • Site-wide: 59,019 out of 64,934

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

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  • Site-wide: 6,565 out of 64,934
  • In genetics: 524 out of 3,683
• Year to date:
  • Site-wide: 2,480 out of 64,934
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  • Site-wide: 3,592 out of 64,934

Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics

• Downloaded 1,037 times
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  • Site-wide: 6,974 out of 64,934
  • In genetics: 549 out of 3,683
• Year to date:
  • Site-wide: 40,666 out of 64,934
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  • Site-wide: 34,603 out of 64,934

Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour

• Downloaded 1,034 times
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  • Site-wide: 7,025 out of 64,934
  • In genetics: 553 out of 3,683
• Year to date:
  • Site-wide: 11,197 out of 64,934
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  • Site-wide: 17,515 out of 64,934

Red Blood Cell Distribution Width: genetic evidence for aging pathways in 116,666 volunteers

• Downloaded 801 times
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  • Site-wide: 10,466 out of 64,934
  • In genomics: 1,524 out of 4,441
• Year to date:
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  • Site-wide: 44,465 out of 64,934

A common allele in FGF21 associated with preference for sugar consumption lowers body fat in the lower body and increases blood pressure

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  • Site-wide: 12,183 out of 64,934
  • In genetics: 853 out of 3,683
• Year to date:
  • Site-wide: 28,979 out of 64,934
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  • Site-wide: 35,140 out of 64,934

Quantifying the extent to which index event biases influence large genetic association studies

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  • In genetics: 1,075 out of 3,683
• Year to date:
  • Site-wide: 56,533 out of 64,934
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  • Site-wide: 52,301 out of 64,934

Evidence that low socioeconomic position accentuates genetic susceptibility to obesity

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  • In genetics: 1,199 out of 3,683
• Year to date:
  • Site-wide: 59,664 out of 64,934
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  • Site-wide: 42,488 out of 64,934

Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause, and impact reproductive health: a UK Biobank study

• Downloaded 512 times
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  • Site-wide: 19,544 out of 64,934
  • In genetics: 1,308 out of 3,683
• Year to date:
  • Site-wide: 47,190 out of 64,934
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  • Site-wide: 39,731 out of 64,934

Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity

• Downloaded 495 times
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  • In genomics: 2,338 out of 4,441
• Year to date:
  • Site-wide: 39,124 out of 64,934
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  • Site-wide: 29,992 out of 64,934

Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

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  • In genetics: 1,405 out of 3,683
• Year to date:
  • Site-wide: 60,559 out of 64,934
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  • Site-wide: 55,498 out of 64,934

Evidence of a common causal relationship between body mass index and inflammatory skin disease: a Mendelian Randomization study

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  • In genetics: 1,509 out of 3,683
• Year to date:
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  • Site-wide: 56,641 out of 64,934

Genome-wide association analysis of excessive daytime sleepiness identifies 42 loci that suggest phenotypic subgroups

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  • In genomics: 2,533 out of 4,441
• Year to date:
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  • Site-wide: 32,948 out of 64,934

Maximum likelihood method quantifies the overall contribution of gene-environment interaction to complex traits: an application to obesity traits

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  • Site-wide: 24,569 out of 64,934
  • In epidemiology: 337 out of 1,556
• Year to date:
  • Site-wide: 7,454 out of 64,934
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  • Site-wide: 13,265 out of 64,934

Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes respectively

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  • In genetics: 1,713 out of 3,683
• Year to date:
  • Site-wide: 51,074 out of 64,934
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  • Site-wide: 40,190 out of 64,934

Effects of body mass index on relationship status, social contact, and socioeconomic position: Mendelian Randomization study in UK Biobank

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  • Site-wide: 34,267 out of 64,934
  • In epidemiology: 539 out of 1,556
• Year to date:
  • Site-wide: 12,758 out of 64,934
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  • Site-wide: 18,719 out of 64,934

Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis

• Downloaded 274 times
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  • In epidemiology: 619 out of 1,556
• Year to date:
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  • Site-wide: 25,573 out of 64,934