Author: Andrew R. Wood

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Preprints

Genetic insights into the biological mechanisms governing human ovarian ageing

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Meta-analysis of genome-wide association studies for height and body mass index in ~700,000 individuals of European ancestry

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A reference panel of 64,976 haplotypes for genotype imputation

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Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease

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Cell specific eQTL analysis without sorting cells

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Investigating causal relationships between sleep traits and risk of breast cancer: a Mendelian randomization study

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Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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Biological and clinical insights from genetics of insomnia symptoms

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Assessing the pathogenicity, penetrance and expressivity of putative disease-causing variants in a population setting

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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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Genome-wide association analyses in >119,000 individuals identifies thirteen morningness and two sleep duration loci

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Mosaic Turner syndrome shows reduced phenotypic penetrance in an adult population study compared to clinically ascertained cases

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Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

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GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

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Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

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Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour

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HUMAN LONGEVITY IS INFLUENCED BY MANY GENETIC VARIANTS: EVIDENCE FROM 75,000 UK BIOBANK PARTICIPANTS

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Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics

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Narrow-sense heritability estimation of complex traits using identity-by-descent information.

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Red Blood Cell Distribution Width: genetic evidence for aging pathways in 116,666 volunteers

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A common allele in FGF21 associated with preference for sugar consumption lowers body fat in the lower body and increases blood pressure

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GWAS identifies novel risk locus for erectile dysfunction and implicates hypothalamic neurobiology and diabetes in etiology

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Quantifying the extent to which index event biases influence large genetic association studies

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Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause, and impact reproductive health: a UK Biobank study

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Evidence that low socioeconomic position accentuates genetic susceptibility to obesity

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Maximum likelihood method quantifies the overall contribution of gene-environment interaction to continuous traits: an application to complex traits in the UK Biobank

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  • In epidemiology: 1,606
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The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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Genetic predictors of participation in optional components of UK Biobank

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Evidence that telomere length is causal for Idiopathic Pulmonary Fibrosis but not Chronic Obstructive Pulmonary Disease: A Mendelian Randomisation Study

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  • Site-wide: 38,718
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Evidence of a common causal relationship between body mass index and inflammatory skin disease: a Mendelian Randomization study

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Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis

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Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

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Genome-wide association analysis of excessive daytime sleepiness identifies 42 loci that suggest phenotypic subgroups

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  • In genomics: 3,450
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Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes respectively

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Genetic determinants of daytime napping and effects on cardiometabolic health

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  • Site-wide: 54,111
  • In genetic and genomic medicine: 141
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Effects of body mass index on relationship status, social contact, and socioeconomic position: Mendelian Randomization study in UK Biobank

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  • Site-wide: 54,287
  • In epidemiology: 2,288
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Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

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Higher maternal adiposity reduces offspring birth weight if associated with a metabolically favourable profile

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  • In genetic and genomic medicine: 385
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Common maternal and fetal genetic variants show expected polygenic effects on the probability of being born small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies

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A Mendelian randomisation study of smoking causality in IPF compared with COPD

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Assessing the causal role of sleep traits on glycated haemoglobin: a Mendelian randomization study

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A genome wide association study of frozen shoulder identifies a common variant of WNT7B and diabetes as causal risk factors

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