Author: Andrew R. Wood

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Preprints

Meta-analysis of genome-wide association studies for height and body mass index in ~700,000 individuals of European ancestry

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  • Site-wide: 1,351
  • In genetics: 46
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  • Site-wide: 18,432
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  • Site-wide: 15,043

A reference panel of 64,976 haplotypes for genotype imputation

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  • Site-wide: 2,246
  • In genetics: 82
• Year to date:
  • Site-wide: 80,861
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  • Site-wide: 97,827

Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease

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  • Site-wide: 6,031
  • In genetics: 284
• Year to date:
  • Site-wide: 37,546
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  • Site-wide: 44,152

Cell specific eQTL analysis without sorting cells

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  • Site-wide: 7,445
  • In genetics: 350
• Year to date:
  • Site-wide: 104,218
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  • Site-wide: 88,943

Biological and clinical insights from genetics of insomnia symptoms

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  • Site-wide: 7,607
  • In genomics: 829
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  • Site-wide: 12,609
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  • Site-wide: 13,830

Investigating causal relationships between sleep traits and risk of breast cancer: a Mendelian randomization study

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  • Site-wide: 7,883
  • In epidemiology: 614
• Year to date:
  • Site-wide: 104,175
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  • Site-wide: 75,228

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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  • Site-wide: 8,411
  • In genetics: 395
• Year to date:
  • Site-wide: 88,437
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  • Site-wide: 90,901

Assessing the pathogenicity, penetrance and expressivity of putative disease-causing variants in a population setting

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  • Site-wide: 8,583
  • In genetics: 403
• Year to date:
  • Site-wide: 68,251
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  • Site-wide: 75,226

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 9,896
  • In genetics: 470
• Year to date:
  • Site-wide: 65,291
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  • Site-wide: 47,085

Mosaic Turner syndrome shows reduced phenotypic penetrance in an adult population study compared to clinically ascertained cases

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  • Site-wide: 9,940
  • In genetics: 474
• Year to date:
  • Site-wide: 41,153
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  • Site-wide: 44,165

Genome-wide association analyses in >119,000 individuals identifies thirteen morningness and two sleep duration loci

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  • Site-wide: 10,060
  • In genetics: 483
• Year to date:
  • Site-wide: 86,644
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  • Site-wide: 105,522

Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

• Downloaded 1,613 times
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  • Site-wide: 10,314
  • In genetics: 499
• Year to date:
  • Site-wide: 54,766
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  • Site-wide: 46,837

GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

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  • Site-wide: 11,418
  • In genetics: 549
• Year to date:
  • Site-wide: 69,789
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  • Site-wide: 63,060

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

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  • Site-wide: 12,487
  • In genetics: 612
• Year to date:
  • Site-wide: 78,262
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  • Site-wide: 53,096

Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour

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  • Site-wide: 14,514
  • In genetics: 719
• Year to date:
  • Site-wide: 78,199
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  • Site-wide: 74,399

HUMAN LONGEVITY IS INFLUENCED BY MANY GENETIC VARIANTS: EVIDENCE FROM 75,000 UK BIOBANK PARTICIPANTS

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  • Site-wide: 15,605
  • In genomics: 1,607
• Year to date:
  • Site-wide: 113,131
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  • Site-wide: 99,771

Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics

• Downloaded 1,203 times
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  • Site-wide: 16,021
  • In genetics: 793
• Year to date:
  • Site-wide: 78,152
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  • Site-wide: 76,024

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

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  • Site-wide: 17,362
  • In genetics: 849
• Year to date:
  • Site-wide: 75,376
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  • Site-wide: 67,243

A common allele in FGF21 associated with preference for sugar consumption lowers body fat in the lower body and increases blood pressure

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  • Site-wide: 22,601
  • In genetics: 1,091
• Year to date:
  • Site-wide: 65,304
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  • Site-wide: 57,020

Red Blood Cell Distribution Width: genetic evidence for aging pathways in 116,666 volunteers

• Downloaded 947 times
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  • Site-wide: 22,715
  • In genomics: 2,217
• Year to date:
  • Site-wide: 103,573
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  • Site-wide: 109,721

GWAS identifies novel risk locus for erectile dysfunction and implicates hypothalamic neurobiology and diabetes in etiology

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  • Site-wide: 24,144
  • In genomics: 2,317
• Year to date:
  • Site-wide: 122,093
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  • Site-wide: 120,765

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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  • Site-wide: 29,177
  • In genetics: 1,415
• Year to date:
  • Site-wide: 14,350
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  • Site-wide: 11,103

Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause, and impact reproductive health: a UK Biobank study

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  • Site-wide: 34,721
  • In genetics: 1,664
• Year to date:
  • Site-wide: 52,077
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  • Site-wide: 39,439

Quantifying the extent to which index event biases influence large genetic association studies

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  • Site-wide: 35,493
  • In genetics: 1,698
• Year to date:
  • Site-wide: 122,087
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  • Site-wide: 129,228

Maximum likelihood method quantifies the overall contribution of gene-environment interaction to continuous traits: an application to complex traits in the UK Biobank

• Downloaded 674 times
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  • Site-wide: 36,524
  • In epidemiology: 1,787
• Year to date:
  • Site-wide: 78,212
• Since beginning of last month:
  • Site-wide: 92,459

Evidence that low socioeconomic position accentuates genetic susceptibility to obesity

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  • Site-wide: 36,920
  • In genetics: 1,765
• Year to date:
  • Site-wide: 99,119
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  • Site-wide: 90,650

Evidence that telomere length is causal for Idiopathic Pulmonary Fibrosis but not Chronic Obstructive Pulmonary Disease: A Mendelian Randomisation Study

• Downloaded 657 times
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  • Site-wide: 37,745
  • In respiratory medicine: 84
• Year to date:
  • Site-wide: 29,733
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  • Site-wide: 34,334

Genetic predictors of participation in optional components of UK Biobank

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  • Site-wide: 39,107
  • In genetics: 1,859
• Year to date:
  • Site-wide: 44,701
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  • Site-wide: 94,166

Genetic insights into the biological mechanisms governing human ovarian ageing

• Downloaded 587 times
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  • Site-wide: 43,632
  • In sexual and reproductive health: 18
• Year to date:
  • Site-wide: 2,396
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  • Site-wide: 7,479

Evidence of a common causal relationship between body mass index and inflammatory skin disease: a Mendelian Randomization study

• Downloaded 579 times
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  • Site-wide: 44,329
  • In genetics: 2,079
• Year to date:
  • Site-wide: 104,459
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  • Site-wide: 99,047

Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis

• Downloaded 579 times
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  • Site-wide: 44,318
  • In epidemiology: 2,080
• Year to date:
  • Site-wide: 95,201
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  • Site-wide: 75,933

Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

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  • Site-wide: 44,764
  • In genetics: 2,099
• Year to date:
  • Site-wide: 111,593
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  • Site-wide: 86,726

Genome-wide association analysis of excessive daytime sleepiness identifies 42 loci that suggest phenotypic subgroups

• Downloaded 572 times
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  • Site-wide: 44,920
  • In genomics: 3,617
• Year to date:
  • Site-wide: 91,218
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  • Site-wide: 81,585

Genetic determinants of daytime napping and effects on cardiometabolic health

• Downloaded 511 times
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  • Site-wide: 51,583
  • In genetic and genomic medicine: 162
• Year to date:
  • Site-wide: 22,535
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  • Site-wide: 36,754

Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes respectively

• Downloaded 507 times
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  • Site-wide: 52,034
  • In genetics: 2,425
• Year to date:
  • Site-wide: 108,433
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  • Site-wide: 117,629

Effects of body mass index on relationship status, social contact, and socioeconomic position: Mendelian Randomization study in UK Biobank

• Downloaded 445 times
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  • Site-wide: 59,996
  • In epidemiology: 2,609
• Year to date:
  • Site-wide: 131,552
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  • Site-wide: 126,724

Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

• Downloaded 411 times
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  • Site-wide: 65,088
  • In genetic and genomic medicine: 208
• Year to date:
  • Site-wide: 36,344
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  • Site-wide: 36,966

A genome wide association study of frozen shoulder identifies a common variant of WNT7B and diabetes as causal risk factors

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  • Site-wide: 85,571
  • In orthopedics: 26
• Year to date:
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  • Site-wide: 10,863

Higher maternal adiposity reduces offspring birth weight if associated with a metabolically favourable profile

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  • Site-wide: 109,236
  • In genetic and genomic medicine: 473
• Year to date:
  • Site-wide: 92,977
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  • Site-wide: 71,126

Common maternal and fetal genetic variants show expected polygenic effects on the probability of being born small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies

• Downloaded 152 times
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  • Site-wide: 117,536
  • In genetics: 5,047
• Year to date:
  • Site-wide: 122,634
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  • Site-wide: 116,125

Assessing the causal role of sleep traits on glycated haemoglobin: a Mendelian randomization study

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  • Site-wide: 120,405
  • In epidemiology: 4,914
• Year to date:
  • Site-wide: 27,148
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  • Site-wide: 33,627

A Mendelian randomisation study of smoking causality in IPF compared with COPD

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  • Site-wide: 122,659
  • In respiratory medicine: 235
• Year to date:
  • Site-wide: 39,495
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  • Site-wide: 104,906