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Author: Rafael A. Irizarry

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  • All-time downloads: 67,369 (rank: 506 out of 363,664)
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    • bioinformatics: 62,363 (rank: 14 out of 31,455)
    • cancer biology: 314 (rank: 15,155 (tie) out of 24,736)
    • genetics: 1,333 (rank: 10,299 (tie) out of 34,067)
    • genomics: 3,359 (rank: 5,508 out of 39,235)

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Preprints

Salmon provides accurate, fast, and bias-aware transcript expression estimates using dual-phase inference

bioinformatics more details view paper
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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

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Modeling of RNA-seq fragment sequence bias reduces systematic errors in transcript abundance estimation

bioinformatics more details view paper
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Alignment and mapping methodology influence transcript abundance estimation

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SAFE-clustering: Single-cell Aggregated (From Ensemble) Clustering for Single-cell RNA-seq Data

bioinformatics more details view paper
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Flexible expressed region analysis for RNA-seq with derfinder

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zingeR: unlocking RNA-seq tools for zero-inflation and single cell applications

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Static And Dynamic DNA Loops Form AP-1 Bound Activation Hubs During Macrophage Development

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Heavy-tailed prior distributions for sequence count data: removing the noise and preserving large differences

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Nonparametric expression analysis using inferential replicate counts

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Comparative analysis of neutrophil and monocyte epigenomes

genomics more details view paper
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MOVIE: Multi-Omics VIsualization of Estimated contributions

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Cell-type specific effects of genetic variation on chromatin accessibility during human neuronal differentiation

genetics more details view paper
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Observation weights to unlock bulk RNA-seq tools for zero inflation and single-cell applications

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Tximeta: reference sequence checksums for provenance identification in RNA-seq

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Terminus enables the discovery of data-driven, robust transcript groups from RNA-seq data

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A junction coverage compatibility score to quantify the reliability of transcript abundance estimates and annotation catalogs

bioinformatics more details view paper
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Multi-omic strategies for transcriptome-wide prediction and association studies

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Assessing exposure effects on gene expression

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Silhouette width using generalized mean - a flexible method for assessing clustering efficiency

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    • Site-wide: 33,194 out of 84,482

A framework for transcriptome-wide association studies in breast cancer in diverse study populations

cancer biology more details view paper
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ACTOR: a latent Dirichlet model to compare expressed isoform proportions to a reference panel

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An approach for normalization and quality control for NanoString RNA expression data

genomics more details view paper
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