Author: Matthias Schlesner

Downloads per author, site-wide

Preprints

The evolutionary history of 2,658 cancers

• Downloaded 9,409 times
• Download rankings, all-time:
  • Site-wide: 746
  • In cancer biology: 8
• Year to date:
  • Site-wide: 20,511
• Since beginning of last month:
  • Site-wide: 50,314

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

• Downloaded 5,465 times
• Download rankings, all-time:
  • Site-wide: 1,528
  • In cancer biology: 22
• Year to date:
  • Site-wide: 2,520
• Since beginning of last month:
  • Site-wide: 6,914

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

• Downloaded 5,228 times
• Download rankings, all-time:
  • Site-wide: 1,630
  • In genomics: 174
• Year to date:
  • Site-wide: 19,096
• Since beginning of last month:
  • Site-wide: 19,444

Computational Pan-Genomics: Status, Promises and Challenges

• Downloaded 4,549 times
• Download rankings, all-time:
  • Site-wide: 1,968
  • In genomics: 224
• Year to date:
  • Site-wide: 20,035
• Since beginning of last month:
  • Site-wide: 15,963

A Comprehensive Assessment of Somatic Mutation Calling in Cancer Genomes

• Downloaded 2,388 times
• Download rankings, all-time:
  • Site-wide: 5,039
  • In genomics: 615
• Year to date:
  • Site-wide: 100,598
• Since beginning of last month:
  • Site-wide: 65,419

Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments

• Downloaded 2,287 times
• Download rankings, all-time:
  • Site-wide: 5,377
  • In genomics: 649
• Year to date:
  • Site-wide: 8,918
• Since beginning of last month:
  • Site-wide: 34,724

A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair

• Downloaded 2,137 times
• Download rankings, all-time:
  • Site-wide: 5,914
  • In genomics: 700
• Year to date:
  • Site-wide: 80,554
• Since beginning of last month:
  • Site-wide: 53,097

Cell segmentation-free inference of cell types from in situ transcriptomics data

• Downloaded 1,873 times
• Download rankings, all-time:
  • Site-wide: 7,179
  • In bioinformatics: 919
• Year to date:
  • Site-wide: 9,994
• Since beginning of last month:
  • Site-wide: 5,656

pheno-seq - linking morphological features to gene expression in 3D cell culture systems

• Downloaded 1,786 times
• Download rankings, all-time:
  • Site-wide: 7,686
  • In genomics: 875
• Year to date:
  • Site-wide: 65,371
• Since beginning of last month:
  • Site-wide: 90,988

Deciphering programs of transcriptional regulation by combined deconvolution of multiple omics layers

• Downloaded 1,623 times
• Download rankings, all-time:
  • Site-wide: 8,926
  • In genomics: 1,024
• Year to date:
  • Site-wide: 40,698
• Since beginning of last month:
  • Site-wide: 52,162

Questioning unexpected CRISPR off-target mutations in vivo

• Downloaded 1,469 times
• Download rankings, all-time:
  • Site-wide: 10,342
  • In genomics: 1,179
• Year to date:
  • Site-wide: 79,293
• Since beginning of last month:
  • Site-wide: 86,839

Genomic footprints of activated telomere maintenance mechanisms in cancer

• Downloaded 1,442 times
• Download rankings, all-time:
  • Site-wide: 10,626
  • In genomics: 1,210
• Year to date:
  • Site-wide: 106,303
• Since beginning of last month:
  • Site-wide: 61,716

ACEseq - allele specific copy number estimation from whole genome sequencing

• Downloaded 1,301 times
• Download rankings, all-time:
  • Site-wide: 12,414
  • In bioinformatics: 1,576
• Year to date:
  • Site-wide: 47,018
• Since beginning of last month:
  • Site-wide: 23,849

Framework For Quality Assessment Of Whole Genome, Cancer Sequences

• Downloaded 1,065 times
• Download rankings, all-time:
  • Site-wide: 16,786
  • In genomics: 1,781
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 102,141

Dissecting intratumor heterogeneity of nodal B cell lymphomas on the transcriptional, genetic, and drug response level

• Downloaded 942 times
• Download rankings, all-time:
  • Site-wide: 20,108
  • In cancer biology: 486
• Year to date:
  • Site-wide: 13,334
• Since beginning of last month:
  • Site-wide: 17,059

Resolving Drug Effects In Patient-Derived Cancer Cells Links Organoid Responses To Genome Alterations

• Downloaded 933 times
• Download rankings, all-time:
  • Site-wide: 20,412
  • In cancer biology: 496
• Year to date:
  • Site-wide: 77,681
• Since beginning of last month:
  • Site-wide: 66,991

Identification and prioritisation of causal variants in human genetic disorders from exome or whole genome sequencing data

• Downloaded 711 times
• Download rankings, all-time:
  • Site-wide: 29,950
  • In bioinformatics: 3,483
• Year to date:
  • Site-wide: 62,734
• Since beginning of last month:
  • Site-wide: 101,944

Globally altered epigenetic landscape and lagging osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone

• Downloaded 425 times
• Download rankings, all-time:
  • Site-wide: 56,018
  • In oncology: 62
• Year to date:
  • Site-wide: 96,325
• Since beginning of last month:
  • Site-wide: 67,447

HTSlib-js: Developer toolkit for a client-side JavaScript interface for HTSlib

• Downloaded 360 times
• Download rankings, all-time:
  • Site-wide: 65,767
  • In bioinformatics: 6,446
• Year to date:
  • Site-wide: 107,625
• Since beginning of last month:
  • Site-wide: 102,723

Reprogramming of stromal fibroblasts by chemotherapy-induced secretion of IFNβ1 drives re-growth of breast cancer cells after treatment.

• Downloaded 192 times
• Download rankings, all-time:
  • Site-wide: 98,762
  • In cancer biology: 3,025
• Year to date:
  • Site-wide: 88,296
• Since beginning of last month:
  • Site-wide: 22,761