Author: Wesley K Thompson

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Preprints

The beneficial effect of sleep on behavioral health problems in youth is disrupted by prenatal cannabis exposure: A causal random forest analysis of ABCD data.

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Towards Reproducible Brain-Wide Association Studies

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Image processing and analysis methods for the Adolescent Brain Cognitive Development Study

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Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

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Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

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  • Site-wide: 10,893
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Gene-experience correlation during cognitive development: Evidence from the Adolescent Brain Cognitive Development (ABCD) StudySM

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Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

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The female protective effect against autism spectrum disorder

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A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator

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Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

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Personalized genetic assessment of age associated Alzheimers disease risk

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Adolescent Brain Cognitive Development (ABCD) Community MRI Collection and Utilities

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  • Site-wide: 33,251
  • In neuroscience: 5,438
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Prediction of Neurocognitive Profiles in Youth From Resting State fMRI

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Germline variants that influence the tumor immune microenvironment also drive response to immunotherapy

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  • In cancer biology: 1,324
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  • Site-wide: 28,289

A simple, consistent estimator of heritability for genome-wide association studies

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  • Site-wide: 49,219
  • In bioinformatics: 4,860
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Reliability and Stability Challenges in ABCD Task fMRI Data

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Spatial gene-by-environment mapping for schizophrenia reveals locale of upbringing effects beyond urban-rural differences

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Multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.

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  • Site-wide: 59,439
  • In genetics: 2,378
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  • Site-wide: 101,759
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The genetic architecture of human cortical folding

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  • Site-wide: 60,735
  • In genomics: 4,227
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Sex-dependent polygenic effects on the clinical progressions of Alzheimer's disease

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  • Site-wide: 61,716
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Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

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  • Site-wide: 68,897
  • In genetics: 2,696
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The Bayesian polyvertex score (PVS-B): a whole-brain phenotypic prediction framework for neuroimaging studies

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  • Site-wide: 74,092
  • In neuroscience: 10,213
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The effect of statistical normalisation on network propagation scores

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  • In bioinformatics: 6,650
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Polygenic hazard score predicts aggressive and fatal prostate cancer in multi-ethnic populations

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  • Site-wide: 74,138
  • In genetic and genomic medicine: 377
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  • Site-wide: 152,872
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Multivariate genome-wide association study on tissue-sensitive diffusion metrics identifies key molecular pathways for axonal growth, synaptogenesis, and astrocyte-mediated neuroinflammation

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  • Site-wide: 77,060
  • In genetics: 3,350
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Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders – findings from a Danish population-based study

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  • Site-wide: 78,581
  • In bioinformatics: 7,278
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FEMA: Fast and efficient mixed-effects algorithm for population-scale whole brain imaging data

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  • Site-wide: 88,451
  • In neuroscience: 22,301
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Bayesian Multivariate Growth Mixture Modeling of Longitudinal Data: An Application to Alzheimer's Disease Study

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Demographic and Mental Health Assessments in the Adolescent Brain and Cognitive Development Study: Updates and Longitudinal Trajectories

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  • Site-wide: 98,816
  • In psychiatry and clinical psychology: 504
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Economic, social, and physiological resilience predict brain structure and cognitive performance in 9 - 10-year-old children

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  • Site-wide: 100,620
  • In neuroscience: 14,691
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Quantifying the polygenic architecture of the human cerebral cortex: Extensive genetic overlap between cortical thickness and surface area

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  • Site-wide: 102,383
  • In neuroscience: 14,499
• Year to date:
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  • Site-wide: 139,326

Semi-Parametric Covariate-Modulated Local False Discovery Rate For Genome-Wide Association Studies

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  • Site-wide: 107,587
  • In bioinformatics: 8,792
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Psychotic-like experiences and polygenic liability in the ABCD Study

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  • Site-wide: 108,124
  • In psychiatry and clinical psychology: 479
• Year to date:
  • Site-wide: 127,549
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Neural vulnerability and hurricane-related media are associated with post-traumatic stress in youth

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  • Site-wide: 139,405
  • In neuroscience: 21,121
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A nonlinear simulation framework supports adjusting for age when analyzing BrainAGE.

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  • Site-wide: 141,244
  • In bioinformatics: 10,744
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Maturational trajectories of white matter microstructure underlying the right presupplementary motor area reflect individual improvements in motor response cancellation in children and adolescents

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  • Site-wide: 152,031
  • In neuroscience: 21,813
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Prostate cancer risk stratification improved across multiple ancestries with new polygenic hazard score

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  • Site-wide: 153,051
  • In genetic and genomic medicine: 957
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  • Site-wide: 114,498

Autoimmune Alleles at the Major Histocompatibility Locus Modify Melanoma Susceptibility

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  • Site-wide: 153,598
  • In cancer biology: 4,655
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Common genetic and clinical risk factors: Association with fatal prostate cancer in the Cohort of Swedish Men

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  • Site-wide: 156,520
  • In genetic and genomic medicine: 981
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Genome-wide by environment interaction study of stressful life events and hospital-treated depression in the iPSYCH2012 sample

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  • Site-wide: 169,920
  • In genetic and genomic medicine: 1,137
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Alcohol Use Disrupts Age-Appropriate Cortical Thinning in Adolescence: A Data Driven Approach

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Only females show a stable association between neuroticism and microstructural asymmetry of the cingulum across childhood and adolescence: A longitudinal DTI study

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