Author: David A Agard
- ORCiD: http://orcid.org/0000-0003-3512-695X
- Most recently observed institution: University of California, San Francisco
Rankings
- All-time downloads: 230,571 (rank: 430 )
- Categories:
- biochemistry: 6,607 (rank: 617 )
- biophysics: 30,581 (rank: 10 )
- cell biology: 3,720 (rank: 1,760 )
- microbiology: 5,624 (rank: 3,569 (tie) )
- molecular biology: 1,241 (rank: 6,323 (tie) )
- neuroscience: 837 (rank: 38,657 (tie) )
- systems biology: 178,840 (rank: 20 (tie) )
Downloads per author, site-wide
Preprints
In situ cryo-electron tomography reveals the asymmetric architecture of mammalian sperm axonemes
biophysics more details view paperNo download data for this paper yet.
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
systems biology more details view paper- Downloaded 179,611 times
- Download rankings, all-time:
- Site-wide: 31
- In systems biology: 1
- Year to date:
- Site-wide: 994
- Since beginning of last month:
- Site-wide: 774
Anisotropic Correction of Beam-induced Motion for Improved Single-particle Electron Cryo-microscopy
biophysics more details view paper- Downloaded 7,440 times
- Download rankings, all-time:
- Site-wide: 1,815
- In biophysics: 17
- Year to date:
- Site-wide: 35,995
- Since beginning of last month:
- Site-wide: 31,277
A simple and robust procedure for preparing graphene-oxide cryo-EM grids
biophysics more details view paper- Downloaded 5,821 times
- Download rankings, all-time:
- Site-wide: 2,532
- In biophysics: 26
- Year to date:
- Site-wide: 37,191
- Since beginning of last month:
- Site-wide: 41,721
Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM
biophysics more details view paper- Downloaded 3,496 times
- Download rankings, all-time:
- Site-wide: 5,092
- In biophysics: 77
- Year to date:
- Site-wide: 2,268
- Since beginning of last month:
- Site-wide: 2,499
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
biophysics more details view paper- Downloaded 3,317 times
- Download rankings, all-time:
- Site-wide: 5,504
- In biophysics: 89
- Year to date:
- Site-wide: 4,624
- Since beginning of last month:
- Site-wide: 5,346
A nucleus-like compartment shields bacteriophage DNA from CRISPR-Cas and restriction nucleases
microbiology more details view paper- Downloaded 2,999 times
- Download rankings, all-time:
- Site-wide: 6,370
- In microbiology: 391
- Year to date:
- Site-wide: 82,135
- Since beginning of last month:
- Site-wide: 85,391
Atomic structure of Hsp90:Cdc37:Cdk4 reveals Hsp90 regulates kinase via dramatic unfolding
biochemistry more details view paper- Downloaded 2,551 times
- Download rankings, all-time:
- Site-wide: 8,063
- In biochemistry: 135
- Year to date:
- Site-wide: 120,061
- Since beginning of last month:
- Site-wide: 148,122
General and robust covalently linked graphene oxide affinity grids for high-resolution cryo-EM
biophysics more details view paper- Downloaded 2,251 times
- Download rankings, all-time:
- Site-wide: 9,674
- In biophysics: 172
- Year to date:
- Site-wide: 102,075
- Since beginning of last month:
- Site-wide: 107,058
A molecular pore spans the double membrane of the coronavirus replication organelle
microbiology more details view paper- Downloaded 1,777 times
- Download rankings, all-time:
- Site-wide: 13,726
- In microbiology: 779
- Year to date:
- Site-wide: 60,267
- Since beginning of last month:
- Site-wide: 63,600
Amino and PEG-Amino Graphene Oxide Grids Enrich and Protect Samples for High-resolution Single Particle Cryo-electron Microscopy
biophysics more details view paper- Downloaded 1,529 times
- Download rankings, all-time:
- Site-wide: 17,253
- In biophysics: 394
- Year to date:
- Site-wide: 88,166
- Since beginning of last month:
- Site-wide: 95,675
Microtubules form by progressively faster tubulin accretion, not by nucleation-elongation
cell biology more details view paper- Downloaded 1,497 times
- Download rankings, all-time:
- Site-wide: 17,814
- In cell biology: 502
- Year to date:
- Site-wide: 119,299
- Since beginning of last month:
- Site-wide: 134,740
Structures of the active HER2/HER3 receptor complex reveal dynamics at the dimerization interface induced by binding of a single ligand
biophysics more details view paper- Downloaded 1,466 times
- Download rankings, all-time:
- Site-wide: 18,357
- In biophysics: 472
- Year to date:
- Site-wide: 13,004
- Since beginning of last month:
- Site-wide: 10,350
GR chaperone cycle mechanism revealed by cryo-EM: inactivation of GR by GR:Hsp90:Hsp70:Hop client-loading complex
biochemistry more details view paper- Downloaded 1,247 times
- Download rankings, all-time:
- Site-wide: 23,582
- In biochemistry: 526
- Year to date:
- Site-wide: 39,576
- Since beginning of last month:
- Site-wide: 23,654
The Atomic Structure of the Microtubule-Nucleating γ-Tubulin Small Complex and its Implications for Regulation
biophysics more details view paper- Downloaded 1,170 times
- Download rankings, all-time:
- Site-wide: 25,994
- In biophysics: 666
- Year to date:
- Site-wide: 129,598
- Since beginning of last month:
- Site-wide: 83,061
GR chaperone cycle mechanism revealed by cryo-EM: reactivation of GR by the GR:Hsp90:p23 client-maturation complex
biophysics more details view paper- Downloaded 1,134 times
- Download rankings, all-time:
- Site-wide: 27,297
- In biophysics: 731
- Year to date:
- Site-wide: 61,465
- Since beginning of last month:
- Site-wide: 69,831
AreTomo: An integrated software package for automated marker-free, motion-corrected cryo-electron tomographic alignment and reconstruction
cell biology more details view paper- Downloaded 1,060 times
- Download rankings, all-time:
- Site-wide: 30,183
- In cell biology: 2,679
- Year to date:
- Site-wide: 1,206
- Since beginning of last month:
- Site-wide: 1,965
Structural Basis of Mitochondrial Receptor Binding and GTP Driven Conformational Constriction by Dynamin-Related Protein 1
biophysics more details view paper- Downloaded 1,049 times
- Download rankings, all-time:
- Site-wide: 30,661
- In biophysics: 825
- Year to date:
- Site-wide: 131,304
- Since beginning of last month:
- Site-wide: 150,744
Mind the gap: micro-expansion joints drastically decrease the bending of FIB-milled cryo-lamellae
microbiology more details view paper- Downloaded 911 times
- Download rankings, all-time:
- Site-wide: 37,759
- In microbiology: 2,111
- Year to date:
- Site-wide: 155,787
- Since beginning of last month:
- Site-wide: 181,775
Cryo-EM structures reveal a multistep mechanism of Hsp90 activation by co-chaperone Aha1
biophysics more details view paper- Downloaded 889 times
- Download rankings, all-time:
- Site-wide: 39,070
- In biophysics: 1,396
- Year to date:
- Site-wide: 20,131
- Since beginning of last month:
- Site-wide: 10,827
Symmetry broken and rebroken during the ATP hydrolysis cycle of the mitochondrial Hsp90 TRAP1
molecular biology more details view paper- Downloaded 808 times
- Download rankings, all-time:
- Site-wide: 44,983
- In molecular biology: 1,211
- Year to date:
- Site-wide: 81,596
- Since beginning of last month:
- Site-wide: 56,884
CM1-driven assembly and activation of Yeast γ-Tubulin Small Complex underlies microtubule nucleation
biochemistry more details view paper- Downloaded 736 times
- Download rankings, all-time:
- Site-wide: 51,416
- In biochemistry: 1,339
- Year to date:
- Site-wide: 64,495
- Since beginning of last month:
- Site-wide: 43,025
Electron Cryo-Tomography Provides Insight into Procentriole Architecture and Assembly Mechanism
cell biology more details view paper- Downloaded 678 times
- Download rankings, all-time:
- Site-wide: 57,613
- In cell biology: 2,404
- Year to date:
- Site-wide: 110,229
- Since beginning of last month:
- Site-wide: 117,332
Entropy Regularized Deconvolution of Cellular Cryo-Transmission Electron Tomograms
biophysics more details view paper- Downloaded 678 times
- Download rankings, all-time:
- Site-wide: 57,683
- In biophysics: 1,927
- Year to date:
- Site-wide: 49,009
- Since beginning of last month:
- Site-wide: 47,050
Cryo-EM reveals the dynamic interplay between mitochondrial Hsp90 and SdhB folding intermediates
biophysics more details view paper- Downloaded 677 times
- Download rankings, all-time:
- Site-wide: 57,712
- In biophysics: 1,987
- Year to date:
- Site-wide: 41,807
- Since beginning of last month:
- Site-wide: 35,364
Cryo-EM analysis of human mitochondrial Hsp90 in multiple tetrameric states
biophysics more details view paper- Downloaded 649 times
- Download rankings, all-time:
- Site-wide: 61,225
- In biophysics: 2,129
- Year to date:
- Site-wide: 41,838
- Since beginning of last month:
- Site-wide: 40,125
Modulation of mitochondrial Hsp90 (TRAP1) ATPase activity by calcium and magnesium
biochemistry more details view paper- Downloaded 634 times
- Download rankings, all-time:
- Site-wide: 63,048
- In biochemistry: 1,632
- Year to date:
- Site-wide: 105,931
- Since beginning of last month:
- Site-wide: 130,473
Spc110 N-Terminal Domains Act Independently to Mediate Stable γ-Tubulin Small Complex Binding and γ-Tubulin Ring Complex Assembly
biochemistry more details view paper- Downloaded 634 times
- Download rankings, all-time:
- Site-wide: 63,039
- In biochemistry: 1,587
- Year to date:
- Site-wide: 183,990
- Since beginning of last month:
- Site-wide: None
Mechanistic Origins of Dynamic Instability in Filaments from the Phage Tubulin, PhuZ
cell biology more details view paper- Downloaded 512 times
- Download rankings, all-time:
- Site-wide: 81,952
- In cell biology: 3,508
- Year to date:
- Site-wide: 167,095
- Since beginning of last month:
- Site-wide: 160,250
The {varphi}PA3 Phage Nucleus is Enclosed by a Self-Assembling, 2D Crystalline Lattice
biochemistry more details view paper- Downloaded 499 times
- Download rankings, all-time:
- Site-wide: 84,349
- In biochemistry: None
- Year to date:
- Site-wide: 3,786
- Since beginning of last month:
- Site-wide: 602
Electron Cryo-Tomography Structure of Axonemal Doublet Microtubule from Tetrahymena thermophila
cell biology more details view paper- Downloaded 475 times
- Download rankings, all-time:
- Site-wide: 89,301
- In cell biology: 4,045
- Year to date:
- Site-wide: 82,928
- Since beginning of last month:
- Site-wide: 71,709
Proteomic analysis of microtubule inner proteins (MIPs) in Rib72 null Tetrahymena cells reveals functional MIPs
molecular biology more details view paper- Downloaded 466 times
- Download rankings, all-time:
- Site-wide: 91,195
- In molecular biology: 2,564
- Year to date:
- Site-wide: 146,503
- Since beginning of last month:
- Site-wide: 169,832
Hsp70 chaperone blocks α-synuclein oligomer formation via a novel engagement mechanism
neuroscience more details view paper- Downloaded 452 times
- Download rankings, all-time:
- Site-wide: 94,059
- In neuroscience: 13,299
- Year to date:
- Site-wide: 147,486
- Since beginning of last month:
- Site-wide: 125,811
Structural features of mTORC2 that control substrate-specific activities.
biochemistry more details view paper- Downloaded 406 times
- Download rankings, all-time:
- Site-wide: 104,696
- In biochemistry: 3,927
- Year to date:
- Site-wide: 5,160
- Since beginning of last month:
- Site-wide: 9,722
Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions
neuroscience more details view paper- Downloaded 400 times
- Download rankings, all-time:
- Site-wide: 106,187
- In neuroscience: 14,997
- Year to date:
- Site-wide: 177,672
- Since beginning of last month:
- Site-wide: 159,147
XMAP215 and γ-tubulin additively promote microtubule nucleation in purified solutions
biochemistry more details view paper- Downloaded 337 times
- Download rankings, all-time:
- Site-wide: 122,888
- In biochemistry: 3,425
- Year to date:
- Site-wide: 183,878
- Since beginning of last month:
- Site-wide: 178,653
The centrosomin CM2 domain is a multi-functional binding domain with distinct cell cycle roles
biochemistry more details view paper- Downloaded 315 times
- Download rankings, all-time:
- Site-wide: 128,998
- In biochemistry: 3,658
- Year to date:
- Site-wide: 167,113
- Since beginning of last month:
- Site-wide: 130,495
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