Author: Hyun Min Kang

Downloads per author, site-wide

Preprints

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

• Downloaded 8,181 times
• Download rankings, all-time:
  • Site-wide: 1,037
  • In genomics: 94
• Year to date:
  • Site-wide: 2,141
• Since beginning of last month:
  • Site-wide: 4,418

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

• Downloaded 5,074 times
• Download rankings, all-time:
  • Site-wide: 1,935
  • In genomics: 191
• Year to date:
  • Site-wide: 24,840
• Since beginning of last month:
  • Site-wide: 19,551

Multiplexing droplet-based single cell RNA-sequencing using natural genetic barcodes

• Downloaded 4,894 times
• Download rankings, all-time:
  • Site-wide: 2,040
  • In bioinformatics: 182
• Year to date:
  • Site-wide: 59,493
• Since beginning of last month:
  • Site-wide: 62,443

A reference panel of 64,976 haplotypes for genotype imputation

• Downloaded 4,585 times
• Download rankings, all-time:
  • Site-wide: 2,239
  • In genetics: 82
• Year to date:
  • Site-wide: 84,316
• Since beginning of last month:
  • Site-wide: 117,871

Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium

• Downloaded 4,185 times
• Download rankings, all-time:
  • Site-wide: 2,543
  • In genomics: 283
• Year to date:
  • Site-wide: 4,070
• Since beginning of last month:
  • Site-wide: 2,775

Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia

• Downloaded 3,367 times
• Download rankings, all-time:
  • Site-wide: 3,499
  • In genetic and genomic medicine: 11
• Year to date:
  • Site-wide: 933
• Since beginning of last month:
  • Site-wide: 911

Functional equivalence of genome sequencing analysis pipelines enables harmonized variant calling across human genetics projects

• Downloaded 2,398 times
• Download rankings, all-time:
  • Site-wide: 5,702
  • In bioinformatics: 646
• Year to date:
  • Site-wide: 65,327
• Since beginning of last month:
  • Site-wide: 74,308

Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans

• Downloaded 1,945 times
• Download rankings, all-time:
  • Site-wide: 7,746
  • In genomics: 844
• Year to date:
  • Site-wide: 91,841
• Since beginning of last month:
  • Site-wide: 74,656

Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries

• Downloaded 1,650 times
• Download rankings, all-time:
  • Site-wide: 9,938
  • In genetics: 477
• Year to date:
  • Site-wide: 78,414
• Since beginning of last month:
  • Site-wide: 70,315

emeraLD: Rapid Linkage Disequilibrium Estimation with Massive Data Sets

• Downloaded 1,493 times
• Download rankings, all-time:
  • Site-wide: 11,450
  • In bioinformatics: 1,395
• Year to date:
  • Site-wide: 46,313
• Since beginning of last month:
  • Site-wide: 49,917

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

• Downloaded 1,138 times
• Download rankings, all-time:
  • Site-wide: 17,298
  • In genetics: 847
• Year to date:
  • Site-wide: 72,276
• Since beginning of last month:
  • Site-wide: 63,128

Population-scale study of eRNA transcription reveals bipartite functional enhancer architecture

• Downloaded 1,129 times
• Download rankings, all-time:
  • Site-wide: 17,501
  • In genomics: 1,800
• Year to date:
  • Site-wide: 32,530
• Since beginning of last month:
  • Site-wide: 26,607

Imputation aware tag SNP selection to improve power for multi-ethnic association studies

• Downloaded 818 times
• Download rankings, all-time:
  • Site-wide: 27,848
  • In genomics: 2,576
• Year to date:
  • Site-wide: 94,405
• Since beginning of last month:
  • Site-wide: 87,329

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

• Downloaded 811 times
• Download rankings, all-time:
  • Site-wide: 28,199
  • In genetic and genomic medicine: 89
• Year to date:
  • Site-wide: 26,220
• Since beginning of last month:
  • Site-wide: 20,722

Integrating Comprehensive Functional Annotations to Boost Power and Accuracy in Gene-Based Association Analysis

• Downloaded 742 times
• Download rankings, all-time:
  • Site-wide: 31,912
  • In genetics: 1,545
• Year to date:
  • Site-wide: 86,831
• Since beginning of last month:
  • Site-wide: 74,300

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

• Downloaded 742 times
• Download rankings, all-time:
  • Site-wide: 31,922
  • In genomics: 2,838
• Year to date:
  • Site-wide: 80,191
• Since beginning of last month:
  • Site-wide: 116,758

Heterogeneous transcriptome response to DNA damage at single cell resolution.

• Downloaded 672 times
• Download rankings, all-time:
  • Site-wide: 36,491
  • In cell biology: 1,471
• Year to date:
  • Site-wide: 34,500
• Since beginning of last month:
  • Site-wide: 42,835

Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes

• Downloaded 617 times
• Download rankings, all-time:
  • Site-wide: 40,775
  • In genetics: 1,942
• Year to date:
  • Site-wide: 4,854
• Since beginning of last month:
  • Site-wide: 14,419

Novel KITLG regulatory variants are associated with lung function in African American children with asthma

• Downloaded 506 times
• Download rankings, all-time:
  • Site-wide: 51,927
  • In allergy and immunology: 70
• Year to date:
  • Site-wide: 49,757
• Since beginning of last month:
  • Site-wide: 38,881

Holistic Characterization of Single Hepatocyte Transcriptome Responses to High Fat Diet

• Downloaded 463 times
• Download rankings, all-time:
  • Site-wide: 57,386
  • In physiology: 356
• Year to date:
  • Site-wide: 38,583
• Since beginning of last month:
  • Site-wide: 31,099

Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis

• Downloaded 435 times
• Download rankings, all-time:
  • Site-wide: 61,192
  • In genomics: 4,483
• Year to date:
  • Site-wide: 99,142
• Since beginning of last month:
  • Site-wide: 106,324

Evaluating Mendelian nephrotic syndrome genes for evidence of risk alleles or oligogenicity that explain heritability

• Downloaded 378 times
• Download rankings, all-time:
  • Site-wide: 70,191
  • In genetics: 3,216
• Year to date:
  • Site-wide: 127,876
• Since beginning of last month:
  • Site-wide: 105,716

Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries

• Downloaded 321 times
• Download rankings, all-time:
  • Site-wide: 80,626
  • In bioinformatics: 7,383
• Year to date:
  • Site-wide: 54,973
• Since beginning of last month:
  • Site-wide: 37,136

FASTQuick: Rapid and comprehensive quality assessment of raw sequence reads

• Downloaded 277 times
• Download rankings, all-time:
  • Site-wide: 89,917
  • In bioinformatics: 7,948
• Year to date:
  • Site-wide: 116,436
• Since beginning of last month:
  • Site-wide: 121,305

Genetic architectures of proximal and distal colorectal cancer are partly distinct

• Downloaded 242 times
• Download rankings, all-time:
  • Site-wide: 97,463
  • In genetic and genomic medicine: 381
• Year to date:
  • Site-wide: 58,946
• Since beginning of last month:
  • Site-wide: 60,130