Author: Christopher D. Brown

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Preprints

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

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The GTEx Consortium atlas of genetic regulatory effects across human tissues

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Local genetic effects on gene expression across 44 human tissues

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Exploiting the GTEx resources to decipher the mechanisms at GWAS loci

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Distant regulatory effects of genetic variation in multiple human tissues

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Transposable element exaptation is the primary source of novelty in the primate gene regulatory landscape

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Many long intergenic non-coding RNAs distally regulate mRNA gene expression levels

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Transposable elements generate regulatory novelty in a tissue-specific fashion

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Mechanisms of tissue-specific genetic regulation revealed by latent factors across eQTLs

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High throughput characterization of genetic effects on DNA:protein binding and gene transcription

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Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx

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Genetic And Epigenetic Fine Mapping Of Complex Trait Associated Loci In The Human Liver

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INFERNO - INFERring the molecular mechanisms of NOncoding genetic variants

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Inferring the molecular mechanisms of noncoding Alzheimer's disease-associated genetic variants

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Longitudinal immune profiling of mild and severe COVID-19 reveals innate and adaptive immune dysfunction and provides an early prediction tool for clinical progression

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A dementia-associated risk variant near TMEM106B alters chromatin architecture and gene expression

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Multiplexed targeted resequencing identifies coding and regulatory variation underlying phenotypic extremes of HDL-cholesterol in humans

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Genomic architecture of Shh dependent cochlear morphogenesis

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