Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 62,482 bioRxiv papers from 277,419 authors.

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Preprints

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

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  • Site-wide: 134 out of 62,482
  • In genetics: 11 out of 3,548
• Year to date:
  • Site-wide: 559 out of 62,482
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  • Site-wide: 1,660 out of 62,482

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 137 out of 62,482
  • In genetics: 13 out of 3,548
• Year to date:
  • Site-wide: 2,274 out of 62,482
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  • Site-wide: 8,448 out of 62,482

Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism

• Downloaded 6,234 times
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  • Site-wide: 266 out of 62,482
  • In genetics: 29 out of 3,548
• Year to date:
  • Site-wide: 107 out of 62,482
• Since beginning of last month:
  • Site-wide: 165 out of 62,482

Genomewide association study identifies 30 loci associated with bipolar disorder

• Downloaded 6,099 times
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  • Site-wide: 282 out of 62,482
  • In genetics: 32 out of 3,548
• Year to date:
  • Site-wide: 288 out of 62,482
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  • Site-wide: 1,957 out of 62,482

Common risk variants identified in autism spectrum disorder

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  • Site-wide: 303 out of 62,482
  • In genetics: 37 out of 3,548
• Year to date:
  • Site-wide: 779 out of 62,482
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  • Site-wide: 2,809 out of 62,482

Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

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  • Site-wide: 2,542 out of 62,482
  • In genetics: 236 out of 3,548
• Year to date:
  • Site-wide: 27,144 out of 62,482
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  • Site-wide: 19,755 out of 62,482

A major role for common genetic variation in anxiety disorders

• Downloaded 1,802 times
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  • Site-wide: 2,663 out of 62,482
  • In genetics: 241 out of 3,548
• Year to date:
  • Site-wide: 1,816 out of 62,482
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  • Site-wide: 3,784 out of 62,482

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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  • Site-wide: 3,246 out of 62,482
  • In genetics: 286 out of 3,548
• Year to date:
  • Site-wide: 45,620 out of 62,482
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  • Site-wide: 47,446 out of 62,482

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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  • In genomics: 837 out of 4,297
• Year to date:
  • Site-wide: 19,128 out of 62,482
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  • Site-wide: 34,662 out of 62,482

ASD and ADHD have a similar burden of rare protein-truncating variants

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  • Site-wide: 5,414 out of 62,482
  • In genetics: 434 out of 3,548
• Year to date:
  • Site-wide: 7,049 out of 62,482
• Since beginning of last month:
  • Site-wide: 7,371 out of 62,482

Minimal phenotyping yields GWAS hits of low specificity for major depression

• Downloaded 1,165 times
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  • Site-wide: 5,492 out of 62,482
  • In genetics: 439 out of 3,548
• Year to date:
  • Site-wide: 2,147 out of 62,482
• Since beginning of last month:
  • Site-wide: 2,462 out of 62,482

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

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  • Site-wide: 6,311 out of 62,482
  • In genetics: 509 out of 3,548
• Year to date:
  • Site-wide: 2,090 out of 62,482
• Since beginning of last month:
  • Site-wide: 3,890 out of 62,482

A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

• Downloaded 1,068 times
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  • Site-wide: 6,358 out of 62,482
  • In genetics: 515 out of 3,548
• Year to date:
  • Site-wide: 15,286 out of 62,482
• Since beginning of last month:
  • Site-wide: 20,915 out of 62,482

Genome-wide association study implicates CHRNA2 in cannabis use disorder

• Downloaded 1,037 times
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  • Site-wide: 6,679 out of 62,482
  • In genomics: 1,088 out of 4,297
• Year to date:
  • Site-wide: 7,369 out of 62,482
• Since beginning of last month:
  • Site-wide: 10,824 out of 62,482

A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator

• Downloaded 1,006 times
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  • Site-wide: 6,981 out of 62,482
  • In genetics: 552 out of 3,548
• Year to date:
  • Site-wide: 14,520 out of 62,482
• Since beginning of last month:
  • Site-wide: 42,038 out of 62,482

Genome-wide Association Study of Anxiety and Stress-related Disorders in the iPSYCH Cohort

• Downloaded 972 times
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  • Site-wide: 7,371 out of 62,482
  • In genetics: 570 out of 3,548
• Year to date:
  • Site-wide: 9,257 out of 62,482
• Since beginning of last month:
  • Site-wide: 13,748 out of 62,482

Mitochondrial DNA SNPs associated with Schizophrenia exhibit Highly Variable Inter-allelic Haplogroup Affiliation and Nuclear Genogeographic Affinity: Bi-Genomic Linkage Disequilibrium raises Major Concerns for Link to Disease

• Downloaded 765 times
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  • Site-wide: 10,697 out of 62,482
  • In genomics: 1,536 out of 4,297
• Year to date:
  • Site-wide: 14,570 out of 62,482
• Since beginning of last month:
  • Site-wide: 15,356 out of 62,482

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 662 times
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  • Site-wide: 13,182 out of 62,482
  • In genetics: 929 out of 3,548
• Year to date:
  • Site-wide: 10,288 out of 62,482
• Since beginning of last month:
  • Site-wide: 26,960 out of 62,482

Pharmacogenetics of antidepressant response: a polygenic approach

• Downloaded 645 times
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  • Site-wide: 13,652 out of 62,482
  • In genetics: 952 out of 3,548
• Year to date:
  • Site-wide: 30,372 out of 62,482
• Since beginning of last month:
  • Site-wide: 24,707 out of 62,482

The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders

• Downloaded 617 times
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  • Site-wide: 14,462 out of 62,482
  • In genetics: 1,006 out of 3,548
• Year to date:
  • Site-wide: 43,841 out of 62,482
• Since beginning of last month:
  • Site-wide: 39,811 out of 62,482

New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

• Downloaded 486 times
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  • Site-wide: 19,780 out of 62,482
  • In genomics: 2,291 out of 4,297
• Year to date:
  • Site-wide: 47,272 out of 62,482
• Since beginning of last month:
  • Site-wide: 45,078 out of 62,482

Elevated polygenic burden for autism is associated with differential DNA methylation at birth.

• Downloaded 486 times
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  • Site-wide: 19,808 out of 62,482
  • In genetics: 1,327 out of 3,548
• Year to date:
  • Site-wide: 40,644 out of 62,482
• Since beginning of last month:
  • Site-wide: 44,044 out of 62,482

The neurobiology of BRD1 implicates sex-biased dysregulation of nuclear receptor signaling in mental disorders

• Downloaded 442 times
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  • Site-wide: 22,178 out of 62,482
  • In neuroscience: 3,726 out of 11,150
• Year to date:
  • Site-wide: 35,014 out of 62,482
• Since beginning of last month:
  • Site-wide: 48,010 out of 62,482

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

• Downloaded 395 times
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  • Site-wide: 25,119 out of 62,482
  • In genetics: 1,639 out of 3,548
• Year to date:
  • Site-wide: 26,957 out of 62,482
• Since beginning of last month:
  • Site-wide: 28,198 out of 62,482

Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depression

• Downloaded 366 times
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  • Site-wide: 27,139 out of 62,482
  • In neuroscience: 4,626 out of 11,150
• Year to date:
  • Site-wide: 23,396 out of 62,482
• Since beginning of last month:
  • Site-wide: None out of 62,482

Exploring contributors to variability in estimates of SNP-heritability and genetic correlations from the iPSYCH case-cohort and published meta-studies of major psychiatric disorders.

• Downloaded 284 times
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  • Site-wide: 34,305 out of 62,482
  • In genetics: 2,148 out of 3,548
• Year to date:
  • Site-wide: 20,395 out of 62,482
• Since beginning of last month:
  • Site-wide: 34,847 out of 62,482

Genetic variation in the Major Histocompatibility Complex and association with depression

• Downloaded 282 times
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  • Site-wide: 34,511 out of 62,482
  • In genetics: 2,161 out of 3,548
• Year to date:
  • Site-wide: 27,752 out of 62,482
• Since beginning of last month:
  • Site-wide: 50,692 out of 62,482

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

• Downloaded 256 times
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  • Site-wide: 37,280 out of 62,482
  • In genetics: 2,295 out of 3,548
• Year to date:
  • Site-wide: 45,091 out of 62,482
• Since beginning of last month:
  • Site-wide: 32,819 out of 62,482

Statin treatment and the risk of depression

• Downloaded 155 times
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  • Site-wide: 49,851 out of 62,482
  • In epidemiology: 1,046 out of 1,556
• Year to date:
  • Site-wide: 42,562 out of 62,482
• Since beginning of last month:
  • Site-wide: 51,402 out of 62,482

Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders – findings from a Danish population-based study

• Downloaded 122 times
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  • Site-wide: 54,233 out of 62,482
  • In bioinformatics: 5,749 out of 6,231
• Year to date:
  • Site-wide: 33,748 out of 62,482
• Since beginning of last month:
  • Site-wide: 30,185 out of 62,482

Identification of risk variants and characterization of the polygenic architecture of disruptive behavior disorders in the context of ADHD

• Downloaded 72 times
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  • Site-wide: 59,349 out of 62,482
  • In genomics: 4,186 out of 4,297
• Year to date:
  • Site-wide: 49,657 out of 62,482
• Since beginning of last month:
  • Site-wide: 5,020 out of 62,482