Author: Ole Mors

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Preprints

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

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  • Site-wide: 3,302
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  • Site-wide: 1,766

Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism

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  • Site-wide: 779
  • In genetics: 22
• Year to date:
  • Site-wide: 5,777
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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 867
  • In genetics: 26
• Year to date:
  • Site-wide: 30,725
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Common risk variants identified in autism spectrum disorder

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  • Site-wide: 1,088
  • In genetics: 33
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  • Site-wide: 2,925
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  • Site-wide: 4,512

Genomewide association study identifies 30 loci associated with bipolar disorder

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  • Site-wide: 1,202
  • In genetics: 38
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  • Site-wide: 18,072
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A Major Role for Common Genetic Variation in Anxiety Disorders

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  • Site-wide: 3,646
  • In genetics: 149
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  • Site-wide: 6,057
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Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

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  • Site-wide: 5,449
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  • Site-wide: 17,354
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Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

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  • Site-wide: 6,844
  • In psychiatry and clinical psychology: 23
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  • Site-wide: 1,351
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Minimal phenotyping yields GWAS hits of reduced specificity for major depression

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  • Site-wide: 7,295
  • In genetics: 345
• Year to date:
  • Site-wide: 41,857
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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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  • Site-wide: 8,829
  • In genetics: 418
• Year to date:
  • Site-wide: 50,860
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  • Site-wide: 68,554

ASD and ADHD have a similar burden of rare protein-truncating variants

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  • Site-wide: 9,164
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  • Site-wide: 33,850
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Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

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  • Site-wide: 9,463
  • In genetics: 453
• Year to date:
  • Site-wide: 20,332
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  • Site-wide: 19,875

Genome-wide association study implicates CHRNA2 in cannabis use disorder

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  • Site-wide: 9,848
  • In genomics: 1,069
• Year to date:
  • Site-wide: 31,343
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  • Site-wide: 32,206

Genetic Architecture of 11 Major Psychiatric Disorders at Biobehavioral, Functional Genomic, and Molecular Genetic Levels of Analysis

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  • Site-wide: 10,543
  • In genetic and genomic medicine: 39
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  • Site-wide: 2,782
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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  • Site-wide: 11,892
  • In genomics: 1,294
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  • Site-wide: 73,719
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  • Site-wide: 72,439

A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

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  • Site-wide: 12,470
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• Year to date:
  • Site-wide: 49,569
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Genome-wide Association Study of Anxiety and Stress-related Disorders in the iPSYCH Cohort

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  • Site-wide: 14,479
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• Year to date:
  • Site-wide: 73,909
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  • Site-wide: 73,210

A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator

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  • Site-wide: 16,777
  • In genetics: 823
• Year to date:
  • Site-wide: 89,241
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  • Site-wide: 83,527

Genome-wide association study of school grades identifies a genetic overlap between language ability, psychopathology and creativity

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  • Site-wide: 18,212
  • In genomics: 1,853
• Year to date:
  • Site-wide: 26,350
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  • Site-wide: 38,303

Mitochondrial DNA SNPs associated with Schizophrenia exhibit Highly Variable Inter-allelic Haplogroup Affiliation and Nuclear Genogeographic Affinity: Bi-Genomic Linkage Disequilibrium raises Major Concerns for Link to Disease

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  • Site-wide: 18,640
  • In genomics: 1,892
• Year to date:
  • Site-wide: 51,038
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  • Site-wide: 42,595

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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  • Site-wide: 18,995
  • In genetics: 924
• Year to date:
  • Site-wide: 3,644
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Complex spatio-temporal distribution and genogeographic affinity of mitochondrial DNA haplogroups in 24,216 Danes

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  • Site-wide: 24,326
  • In genomics: 2,330
• Year to date:
  • Site-wide: 63,928
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  • Site-wide: 61,053

Pharmacogenetics of antidepressant response: a polygenic approach

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  • Site-wide: 24,668
  • In genetics: 1,187
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  • Site-wide: 83,012
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  • Site-wide: 89,839

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

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  • Site-wide: 26,717
  • In genetics: 1,293
• Year to date:
  • Site-wide: 76,514
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  • Site-wide: 72,421

Cross-validation of technologies for genotyping CYP2D6 and CYP2C19

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  • Site-wide: 28,140
  • In genetics: 1,368
• Year to date:
  • Site-wide: 19,848
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  • Site-wide: 24,999

The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders

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  • Site-wide: 30,019
  • In genetics: 1,455
• Year to date:
  • Site-wide: 71,020
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  • Site-wide: 95,852

The neurobiology of BRD1 implicates sex-biased dysregulation of nuclear receptor signaling in mental disorders

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  • Site-wide: 37,029
  • In neuroscience: 5,191
• Year to date:
  • Site-wide: 61,903
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  • Site-wide: 67,667

Elevated polygenic burden for autism is associated with differential DNA methylation at birth.

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  • Site-wide: 38,649
  • In genetics: 1,838
• Year to date:
  • Site-wide: 103,111
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  • Site-wide: 96,335

Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depression

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  • Site-wide: 41,311
  • In neuroscience: 5,902
• Year to date:
  • Site-wide: 74,115
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  • Site-wide: 65,624

New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

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  • Site-wide: 43,298
  • In genomics: 3,527
• Year to date:
  • Site-wide: 123,111
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  • Site-wide: 107,984

Identification of risk variants and characterization of the polygenic architecture of disruptive behavior disorders in the context of ADHD

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  • Site-wide: 43,861
  • In genomics: 3,566
• Year to date:
  • Site-wide: 47,633
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  • Site-wide: 46,223

Exploring contributors to variability in estimates of SNP-heritability and genetic correlations from the iPSYCH case-cohort and published meta-studies of major psychiatric disorders.

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  • Site-wide: 47,752
  • In genetics: 2,242
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  • Site-wide: 85,777
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  • Site-wide: 78,419

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

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  • Site-wide: 49,855
  • In genetics: 2,330
• Year to date:
  • Site-wide: 109,690
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  • Site-wide: 101,329

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

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  • Site-wide: 51,539
  • In genetics: 2,400
• Year to date:
  • Site-wide: 119,451
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  • Site-wide: 109,666

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

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  • Site-wide: 52,421
  • In genetic and genomic medicine: 167
• Year to date:
  • Site-wide: 10,930
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  • Site-wide: 9,694

Meta-analysis of Scandinavian Schizophrenia Exomes

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  • Site-wide: 59,544
  • In genetics: 2,765
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  • Site-wide: 59,397
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  • Site-wide: 75,633

Genetic variation in the Major Histocompatibility Complex and association with depression

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  • Site-wide: 62,128
  • In genetics: 2,876
• Year to date:
  • Site-wide: 115,333
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  • Site-wide: 89,571

Antidepressant Response in Major Depressive Disorder: A Genome-wide Association Study

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  • Site-wide: 74,212
  • In psychiatry and clinical psychology: 233
• Year to date:
  • Site-wide: 9,388
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  • Site-wide: 24,681

Polygenic prediction of school performance in children with and without psychiatric disorders

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  • Site-wide: 80,735
  • In genetics: 3,672
• Year to date:
  • Site-wide: 78,383
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  • Site-wide: 114,223

Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders – findings from a Danish population-based study

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  • Site-wide: 84,842
  • In bioinformatics: 7,636
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  • Site-wide: 56,273

Statin treatment and the risk of depression

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  • Site-wide: 89,651
  • In epidemiology: 3,681
• Year to date:
  • Site-wide: 74,360
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  • Site-wide: 66,232

The iPSYCH2015 Case-Cohort sample: updated directions for unravelling genetic and environmental architectures of severe mental disorders

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  • Site-wide: 113,331
  • In epidemiology: 4,655
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  • Site-wide: 23,324
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  • Site-wide: 22,687

Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression

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  • Site-wide: 120,722
  • In psychiatry and clinical psychology: 553
• Year to date:
  • Site-wide: 18,019
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  • Site-wide: 9,941

Genome-wide association study of febrile seizures identifies seven new loci implicating fever response and neuronal excitability genes

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  • Site-wide: 122,426
  • In genetic and genomic medicine: 579
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  • Site-wide: 53,609