Author: Kristen J. Brennand

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Preprints

Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia

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An Efficient Platform For Astrocyte Differentiation From Human Induced Pluripotent Stem Cells

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Functional annotation of rare structural variation in the human brain

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Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection

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Publicly available hiPSC lines with extreme polygenic risk scores for modeling schizophrenia

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Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with signatures from post mortem adult brains

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Transcriptional signatures of participant-derived neural progenitor cells and neurons implicate altered Wnt signaling in Phelan McDermid syndrome and autism

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Schizophrenia hiPSC neurons display expression changes that are enriched for disease risk variants and a blunted activity-dependent response

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Circadian rhythms in bipolar disorder patient-derived neurons predict lithium response

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Fitness selection of hyperfusogenic measles virus F proteins associated with neuropathogenic phenotypes

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