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Author: Michael J Owen

  • ORCiD: http://orcid.org/0000-0003-4798-0862
  • Most recently observed institution: MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK

Rankings

  • All-time downloads: 53,086 (rank: 2,473 )
  • Categories:
    • genetic and genomic medicine: 4,437 (rank: 131 )
    • genetics: 31,316 (rank: 174 )
    • genomics: 10,946 (rank: 1,586 )
    • neuroscience: 3,656 (rank: 5,176 )
    • pharmacology and therapeutics: 64 (rank: 718 (tie) )
    • psychiatry and clinical psychology: 2,667 (rank: 158 (tie) )

Downloads per author, site-wide

Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

genetics more details view paper
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    • Site-wide: 812
    • In genetics: 25
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    • Site-wide: 22,329
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Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
  • Downloaded 7,266 times
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    • Site-wide: 1,126
    • In genetics: 38
  • Year to date:
    • Site-wide: 14,555
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    • Site-wide: 14,555

Genetic Identification Of Brain Cell Types Underlying Schizophrenia

genomics more details view paper
  • Downloaded 3,585 times
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    • Site-wide: 2,983
    • In genomics: 350
  • Year to date:
    • Site-wide: 62,684
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    • Site-wide: 62,684

Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia

genetic and genomic medicine more details view paper
  • Downloaded 2,861 times
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    • Site-wide: 4,087
    • In genetic and genomic medicine: 11
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Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

genomics more details view paper
  • Downloaded 2,496 times
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    • Site-wide: 5,024
    • In genomics: 591
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Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits

genetics more details view paper
  • Downloaded 2,154 times
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    • Site-wide: 6,216
    • In genetics: 307
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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

genetics more details view paper
  • Downloaded 1,772 times
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    • Site-wide: 8,317
    • In genetics: 408
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Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights

psychiatry and clinical psychology more details view paper
  • Downloaded 1,557 times
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    • In psychiatry and clinical psychology: 32
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    • Site-wide: 2,456
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
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Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

genetics more details view paper
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    • Site-wide: 11,245
    • In genetics: 560
  • Year to date:
    • Site-wide: 12,254
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Causal Analyses, Statistical Efficiency And Phenotypic Precision Through Recall-By-Genotype Study Design

genetics more details view paper
  • Downloaded 1,122 times
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    • Site-wide: 16,492
    • In genetics: 834
  • Year to date:
    • Site-wide: 29,274
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Medical consequences of pathogenic CNVs in adults: Analysis of the UK Biobank

genomics more details view paper
  • Downloaded 1,040 times
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    • Site-wide: 18,493
    • In genomics: 1,906
  • Year to date:
    • Site-wide: 91,066
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    • Site-wide: 91,066

Rare loss-of-function variants in KMT2F are associated with schizophrenia and developmental disorders

genomics more details view paper
  • Downloaded 1,015 times
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    • Site-wide: 19,192
    • In genomics: 1,968
  • Year to date:
    • Site-wide: 70,278
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Rare schizophrenia risk variants are enriched in genes shared with neurodevelopmental disorders

genetics more details view paper
  • Downloaded 989 times
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    • Site-wide: 19,884
    • In genetics: 991
  • Year to date:
    • Site-wide: 97,494
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Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

genetics more details view paper
  • Downloaded 831 times
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    • Site-wide: 25,523
    • In genetics: 1,266
  • Year to date:
    • Site-wide: 63,634
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Genetic association study of psychotic experiences in UK Biobank

genetics more details view paper
  • Downloaded 773 times
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    • Site-wide: 28,191
    • In genetics: 1,404
  • Year to date:
    • Site-wide: 54,166
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A Genetics-First Approach to Dissecting the Heterogeneity of Autism: Phenotypic Comparison of Autism Risk Copy Number Variants

psychiatry and clinical psychology more details view paper
  • Downloaded 748 times
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    • Site-wide: 29,546
    • In psychiatry and clinical psychology: 93
  • Year to date:
    • Site-wide: 6,128
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    • Site-wide: 6,128

Association between schizophrenia and both loss of function and missense mutations in paralog conserved sites of voltage-gated sodium channels

genetics more details view paper
  • Downloaded 734 times
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    • Site-wide: 30,280
    • In genetics: 1,508
  • Year to date:
    • Site-wide: 104,696
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Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia

genetics more details view paper
  • Downloaded 732 times
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    • Site-wide: 63,054
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Different complement immune pathways mediate innate and learned aversion

neuroscience more details view paper
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    • In neuroscience: 4,520
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Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

genetics more details view paper
  • Downloaded 698 times
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    • Site-wide: 32,468
    • In genetics: 1,615
  • Year to date:
    • Site-wide: 70,330
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    • Site-wide: 70,330

A Transcriptome Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia

genetics more details view paper
  • Downloaded 627 times
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    • Site-wide: 37,490
    • In genetics: 1,831
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    • Site-wide: 78,228
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    • Site-wide: 78,228

Synaptic protein DLG2 controls neurogenic transcriptional programs disrupted in schizophrenia and related disorders

genetics more details view paper
  • Downloaded 616 times
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    • Site-wide: 38,297
    • In genetics: 1,874
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    • Site-wide: 14,715
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Analyses of rare and common alleles in parent-proband trios implicate rare missense variants in SLC6A1 in schizophrenia and confirm the involvement of loss of function intolerant and neurodevelopmental disorder genes.

genetics more details view paper
  • Downloaded 576 times
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    • Site-wide: 41,692
    • In genetics: 2,004
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    • Site-wide: 54,856
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    • Site-wide: 54,856

Genetic association of FMRP targets with psychiatric disorders

neuroscience more details view paper
  • Downloaded 527 times
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    • Site-wide: 46,546
    • In neuroscience: 6,828
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    • Site-wide: 35,167
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The general impact of haploinsufficiency on brain connectivity underlies the pleiotropic effect of neuropsychiatric CNVs

genetic and genomic medicine more details view paper
  • Downloaded 525 times
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    • Site-wide: 46,738
    • In genetic and genomic medicine: 135
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    • Site-wide: 45,358
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Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations

genetics more details view paper
  • Downloaded 509 times
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    • Site-wide: 48,409
    • In genetics: 2,318
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    • Site-wide: 18,593
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Haploinsufficiency of the psychiatric risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms

neuroscience more details view paper
  • Downloaded 474 times
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    • Site-wide: 52,517
    • In neuroscience: 7,875
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    • Site-wide: 58,417
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Dynamic expression of risk genes for schizophrenia and bipolar disorder across development

neuroscience more details view paper
  • Downloaded 473 times
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    • In neuroscience: 7,892
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The role of rare copy number variants in depression

neuroscience more details view paper
  • Downloaded 452 times
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    • Site-wide: 55,337
    • In neuroscience: 8,318
  • Year to date:
    • Site-wide: 51,333
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    • Site-wide: 51,333

Effects of pathogenic CNVs on physical traits in participants of the UK Biobank

genetics more details view paper
  • Downloaded 444 times
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    • Site-wide: 56,395
    • In genetics: 2,678
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    • Site-wide: 48,465
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Meta-analysis of Scandinavian Schizophrenia Exomes

genetics more details view paper
  • Downloaded 438 times
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    • Site-wide: 57,307
    • In genetics: 2,705
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    • Site-wide: 36,824
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Cyfip1 haploinsufficiency is associated with white matter changes, myelin thinning, reduction of mature oligodendrocytes and behavioural inflexibility

neuroscience more details view paper
  • Downloaded 431 times
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    • Site-wide: 58,155
    • In neuroscience: 8,805
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    • Site-wide: 96,310
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    • Site-wide: 96,310

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

genetic and genomic medicine more details view paper
  • Downloaded 414 times
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    • Site-wide: 60,698
    • In genetic and genomic medicine: 180
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    • Site-wide: 9,488
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Neuropsychiatric copy number variants exert shared effects on human brain structure

genetic and genomic medicine more details view paper
  • Downloaded 409 times
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    • Site-wide: 61,333
    • In genetic and genomic medicine: 184
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    • Site-wide: 28,961
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Novel Insight into the Aetiology of Autism Spectrum Disorder Gained by Integrating Expression Data with Genome-wide Association Statistics

genomics more details view paper
  • Downloaded 392 times
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    • Site-wide: 63,933
    • In genomics: 4,619
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    • Site-wide: 118,583
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Differences in Genetic Liability for Insomnia and Hypersomnia in Bipolar Disorder Subtypes

genomics more details view paper
  • Downloaded 356 times
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    • Site-wide: 69,857
    • In genomics: 4,874
  • Year to date:
    • Site-wide: 99,983
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The rate of de novo CNVs in healthy controls

genomics more details view paper
  • Downloaded 335 times
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    • In genomics: 5,016
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Electrophysiological network alterations in adults with copy number variants associated with high neurodevelopmental risk

neuroscience more details view paper
  • Downloaded 299 times
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    • In neuroscience: 12,458
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Effects of pathogenic CNVs on biochemical markers: a study on the UK Biobank

genomics more details view paper
  • Downloaded 280 times
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Emotional and behavioural phenotypes in young people with neurodevelopmental CNVs

psychiatry and clinical psychology more details view paper
  • Downloaded 276 times
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    • Site-wide: 85,120
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A brief report: de novo copy number variants in children with attention deficit hyperactivity disorder

genetic and genomic medicine more details view paper
  • Downloaded 228 times
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    • Site-wide: 95,402
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Coordination difficulties, IQ and psychopathology in children with high-risk Copy Number Variants

genetics more details view paper
  • Downloaded 227 times
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    • Site-wide: 95,597
    • In genetics: 4,358
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Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by mutation of the psychiatric risk gene Cacna1c

neuroscience more details view paper
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    • Site-wide: 100,859
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Developmental profile of psychiatric risk associated with voltage-gated cation channel activity

neuroscience more details view paper
  • Downloaded 99 times
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    • In neuroscience: 18,747
  • Year to date:
    • Site-wide: 75,015
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Psychopathology in mothers of children with pathogenic Copy Number Variants

psychiatry and clinical psychology more details view paper
  • Downloaded 86 times
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    • Site-wide: 122,920
    • In psychiatry and clinical psychology: 582
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    • Site-wide: 108,919
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Clozapine metabolism is associated with Absolute Neutrophil Count in individuals with treatment-resistant schizophrenia

pharmacology and therapeutics more details view paper
  • Downloaded 64 times
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    • Site-wide: 125,706
    • In pharmacology and therapeutics: 97
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    • Site-wide: 18,012
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