Author: M. Arfan Ikram

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Preprints

The genetic architecture of the human cerebral cortex

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GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

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Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

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A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

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Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

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Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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Equivalence of LD-Score Regression and Individual-Level-Data Methods

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Grey Matter Age Prediction as a Biomarker for Risk of Dementia: A Population-based Study

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Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

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Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption

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Exome sequencing identifies novel AD-associated genes.

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Planar cell polarity pathway and development of the human visual cortex

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Partial derivatives meta-analysis: pooled analyses when individual participant data cannot be shared

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Relationship between gut microbiota and circulating metabolites in population-based cohorts

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Genome-wide Association Study Links APOEϵ4 and BACE1 Variants with Plasma Amyloid β Levels

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Novel genetic loci affecting facial shape variation in humans

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The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference

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Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

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Meta-analysis of exome array data identifies six novel genetic loci for lung function

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GenNet framework: interpretable neural networks for phenotype prediction

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Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

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High-dimensional mapping of cognition to the brain using voxel-based morphometry and subcortical shape analysis.

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Genetic variants for head size share genes and pathways with cancer

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KCND3 is a novel susceptibility locus for early repolarization

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Correction for both common and rare cell types in blood is important to identify genes that correlate with age

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Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

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Investigating the relationships between unfavorable sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses

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