Author: Oleksandr Frei

Downloads per author, site-wide

Preprints

Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

• Downloaded 2,727 times
• Download rankings, all-time:
  • Site-wide: 2,148 out of 88,403
  • In genomics: 421 out of 5,641
• Year to date:
  • Site-wide: 3,831 out of 88,403
• Since beginning of last month:
  • Site-wide: 4,789 out of 88,403

Genetics of brain age suggest an overlap with common brain disorders

• Downloaded 2,516 times
• Download rankings, all-time:
  • Site-wide: 2,471 out of 88,403
  • In neuroscience: 334 out of 15,736
• Year to date:
  • Site-wide: 15,188 out of 88,403
• Since beginning of last month:
  • Site-wide: 21,131 out of 88,403

A global view of pleiotropy and genetic architecture in complex traits

• Downloaded 2,333 times
• Download rankings, all-time:
  • Site-wide: 2,802 out of 88,403
  • In genetics: 220 out of 4,590
• Year to date:
  • Site-wide: 11,318 out of 88,403
• Since beginning of last month:
  • Site-wide: 11,770 out of 88,403

Estimating inflation in GWAS summary statistics due to variance distortion from cryptic relatedness

• Downloaded 1,450 times
• Download rankings, all-time:
  • Site-wide: 6,136 out of 88,403
  • In genomics: 993 out of 5,641
• Year to date:
  • Site-wide: 9,584 out of 88,403
• Since beginning of last month:
  • Site-wide: 5,998 out of 88,403

Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

• Downloaded 1,161 times
• Download rankings, all-time:
  • Site-wide: 8,893 out of 88,403
  • In genetics: 635 out of 4,590
• Year to date:
  • Site-wide: 46,287 out of 88,403
• Since beginning of last month:
  • Site-wide: 35,081 out of 88,403

A genome-wide genetic pleiotropy approach identified shared loci between multiple system atrophy and inflammatory bowel disease

• Downloaded 751 times
• Download rankings, all-time:
  • Site-wide: 17,720 out of 88,403
  • In genetics: 1,139 out of 4,590
• Year to date:
  • Site-wide: 15,436 out of 88,403
• Since beginning of last month:
  • Site-wide: 21,708 out of 88,403

Brain scans from 21297 individuals reveal the genetic architecture of hippocampal subfield volumes

• Downloaded 660 times
• Download rankings, all-time:
  • Site-wide: 21,412 out of 88,403
  • In genetics: 1,360 out of 4,590
• Year to date:
  • Site-wide: 64,615 out of 88,403
• Since beginning of last month:
  • Site-wide: 49,895 out of 88,403

Evidence of natural selection in human complex phenotypes from GWAS summary statistics

• Downloaded 648 times
• Download rankings, all-time:
  • Site-wide: 22,014 out of 88,403
  • In genomics: 2,503 out of 5,641
• Year to date:
  • Site-wide: 8,230 out of 88,403
• Since beginning of last month:
  • Site-wide: 4,521 out of 88,403

Making the MOSTest of imaging genetics

• Downloaded 577 times
• Download rankings, all-time:
  • Site-wide: 25,880 out of 88,403
  • In neuroscience: 4,363 out of 15,736
• Year to date:
  • Site-wide: 12,382 out of 88,403
• Since beginning of last month:
  • Site-wide: 8,296 out of 88,403

The genetic architecture of human brainstem structures and their involvement in common brain disorders

• Downloaded 575 times
• Download rankings, all-time:
  • Site-wide: 26,025 out of 88,403
  • In neuroscience: 4,390 out of 15,736
• Year to date:
  • Site-wide: 14,058 out of 88,403
• Since beginning of last month:
  • Site-wide: 20,618 out of 88,403

Cortico-genetic mapping links individual brain maturity in youths to cognitive and psychiatric traits

• Downloaded 575 times
• Download rankings, all-time:
  • Site-wide: 26,002 out of 88,403
  • In neuroscience: 4,394 out of 15,736
• Year to date:
  • Site-wide: 55,490 out of 88,403
• Since beginning of last month:
  • Site-wide: 44,186 out of 88,403

Genetic control of variability in subcortical and intracranial volumes

• Downloaded 455 times
• Download rankings, all-time:
  • Site-wide: 34,684 out of 88,403
  • In neuroscience: 5,959 out of 15,736
• Year to date:
  • Site-wide: 45,132 out of 88,403
• Since beginning of last month:
  • Site-wide: 52,180 out of 88,403

Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

• Downloaded 390 times
• Download rankings, all-time:
  • Site-wide: 41,158 out of 88,403
  • In genetics: 2,404 out of 4,590
• Year to date:
  • Site-wide: 73,200 out of 88,403
• Since beginning of last month:
  • Site-wide: 66,757 out of 88,403

Annotation-Informed Causal Mixture Modeling (AI-MiXeR) reveals phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories

• Downloaded 315 times
• Download rankings, all-time:
  • Site-wide: 50,474 out of 88,403
  • In genetics: 2,879 out of 4,590
• Year to date:
  • Site-wide: 48,895 out of 88,403
• Since beginning of last month:
  • Site-wide: 57,349 out of 88,403

Quantifying the polygenic architecture of the human cerebral cortex: Extensive genetic overlap between cortical thickness and surface area

• Downloaded 295 times
• Download rankings, all-time:
  • Site-wide: 53,282 out of 88,403
  • In neuroscience: 9,418 out of 15,736
• Year to date:
  • Site-wide: 23,099 out of 88,403
• Since beginning of last month:
  • Site-wide: 19,367 out of 88,403

Population-based body-brain mapping links brain morphology and body composition

• Downloaded 178 times
• Download rankings, all-time:
  • Site-wide: 72,356 out of 88,403
  • In neuroscience: 12,931 out of 15,736
• Year to date:
  • Site-wide: 18,076 out of 88,403
• Since beginning of last month:
  • Site-wide: 33,867 out of 88,403

Fast qualitY conTrol meThod foR derIved diffUsion Metrics (YTTRIUM) in big data analysis: UK Biobank 18608 example

• Downloaded 121 times
• Download rankings, all-time:
  • Site-wide: 80,368 out of 88,403
  • In neuroscience: 14,389 out of 15,736
• Year to date:
  • Site-wide: 30,001 out of 88,403
• Since beginning of last month:
  • Site-wide: 44,559 out of 88,403