Author: Srdjan Djurovic

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Preprints

The genetic architecture of the human cerebral cortex

• Downloaded 7,906 times
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  • Site-wide: 1,018
  • In genetics: 30
• Year to date:
  • Site-wide: 18,601
• Since beginning of last month:
  • Site-wide: None

Common risk variants identified in autism spectrum disorder

• Downloaded 7,739 times
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  • Site-wide: 1,055
  • In genetics: 34
• Year to date:
  • Site-wide: 2,156
• Since beginning of last month:
  • Site-wide: 2,441

Genomewide association study identifies 30 loci associated with bipolar disorder

• Downloaded 7,266 times
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  • Site-wide: 1,141
  • In genetics: 38
• Year to date:
  • Site-wide: 17,653
• Since beginning of last month:
  • Site-wide: 16,726

Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimers disease risk

• Downloaded 5,186 times
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  • Site-wide: 1,775
  • In genetics: 66
• Year to date:
  • Site-wide: 26,059
• Since beginning of last month:
  • Site-wide: 35,371

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

• Downloaded 5,134 times
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  • Site-wide: 1,799
  • In genetics: 68
• Year to date:
  • Site-wide: 28,487
• Since beginning of last month:
  • Site-wide: None

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 3,247 times
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  • Site-wide: 3,486
  • In genetics: 148
• Year to date:
  • Site-wide: 28,259
• Since beginning of last month:
  • Site-wide: 31,483

Genetics of brain age suggest an overlap with common brain disorders

• Downloaded 2,686 times
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  • Site-wide: 4,551
  • In neuroscience: 416
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: None

New insights on the genetic etiology of Alzheimer and related dementia

• Downloaded 2,373 times
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  • Site-wide: 5,457
  • In neurology: 11
• Year to date:
  • Site-wide: 1,091
• Since beginning of last month:
  • Site-wide: 1,124

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

• Downloaded 1,779 times
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  • Site-wide: 8,341
  • In genetics: 405
• Year to date:
  • Site-wide: 33,547
• Since beginning of last month:
  • Site-wide: 29,036

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

• Downloaded 1,700 times
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  • Site-wide: 8,966
  • In genetics: 444
• Year to date:
  • Site-wide: 103,798
• Since beginning of last month:
  • Site-wide: None

Largest GWAS (N=1,126,563) of Alzheimer's Disease Implicates Microglia and Immune Cells

• Downloaded 1,674 times
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  • Site-wide: 9,181
  • In genetic and genomic medicine: 26
• Year to date:
  • Site-wide: 2,546
• Since beginning of last month:
  • Site-wide: 2,697

Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights

• Downloaded 1,557 times
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  • Site-wide: 10,193
  • In psychiatry and clinical psychology: 32
• Year to date:
  • Site-wide: 2,956
• Since beginning of last month:
  • Site-wide: 4,206

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,447 times
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  • Site-wide: 11,344
  • In genomics: 1,261
• Year to date:
  • Site-wide: 64,487
• Since beginning of last month:
  • Site-wide: 64,528

Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

• Downloaded 1,247 times
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  • Site-wide: 14,191
  • In genetics: 727
• Year to date:
  • Site-wide: 59,919
• Since beginning of last month:
  • Site-wide: 54,229

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

• Downloaded 893 times
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  • Site-wide: 23,264
  • In genetics: 1,151
• Year to date:
  • Site-wide: 3,800
• Since beginning of last month:
  • Site-wide: 3,302

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 835 times
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  • Site-wide: 25,575
  • In genetics: 1,261
• Year to date:
  • Site-wide: 60,022
• Since beginning of last month:
  • Site-wide: 46,711

Planar cell polarity pathway and development of the human visual cortex

• Downloaded 757 times
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  • Site-wide: 29,301
  • In neuroscience: 4,002
• Year to date:
  • Site-wide: 48,195
• Since beginning of last month:
  • Site-wide: 64,172

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

• Downloaded 750 times
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  • Site-wide: 29,718
  • In genetics: 1,467
• Year to date:
  • Site-wide: 113,372
• Since beginning of last month:
  • Site-wide: None

The genetic architecture of human brainstem structures and their involvement in common brain disorders

• Downloaded 719 times
• Download rankings, all-time:
  • Site-wide: 31,519
  • In neuroscience: 4,374
• Year to date:
  • Site-wide: 74,186
• Since beginning of last month:
  • Site-wide: 67,748

Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

• Downloaded 701 times
• Download rankings, all-time:
  • Site-wide: 32,626
  • In genomics: 2,909
• Year to date:
  • Site-wide: 116,729
• Since beginning of last month:
  • Site-wide: 99,074

Brain scans from 21297 individuals reveal the genetic architecture of hippocampal subfield volumes

• Downloaded 699 times
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  • Site-wide: 32,741
  • In genetics: 1,618
• Year to date:
  • Site-wide: 82,453
• Since beginning of last month:
  • Site-wide: 65,092

The dark side of the mean: brain structural heterogeneity in schizophrenia and its polygenic risk.

• Downloaded 528 times
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  • Site-wide: 46,833
  • In neuroscience: 6,874
• Year to date:
  • Site-wide: 66,636
• Since beginning of last month:
  • Site-wide: 80,964

Genetic control of variability in subcortical and intracranial volumes

• Downloaded 513 times
• Download rankings, all-time:
  • Site-wide: 48,364
  • In neuroscience: 7,158
• Year to date:
  • Site-wide: 82,186
• Since beginning of last month:
  • Site-wide: 63,129

Association between schizophrenia polygenic score and psychotic symptoms in Alzheimer disease: meta-analysis of 11 cohort studies

• Downloaded 502 times
• Download rankings, all-time:
  • Site-wide: 49,643
  • In genomics: 3,929
• Year to date:
  • Site-wide: 76,560
• Since beginning of last month:
  • Site-wide: 82,380

Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

• Downloaded 490 times
• Download rankings, all-time:
  • Site-wide: 51,026
  • In genomics: 4,012
• Year to date:
  • Site-wide: 93,533
• Since beginning of last month:
  • Site-wide: None

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

• Downloaded 414 times
• Download rankings, all-time:
  • Site-wide: 61,071
  • In genetic and genomic medicine: 184
• Year to date:
  • Site-wide: 11,507
• Since beginning of last month:
  • Site-wide: 19,585

Annotation-Informed Causal Mixture Modeling (AI-MiXeR) reveals phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories

• Downloaded 370 times
• Download rankings, all-time:
  • Site-wide: 68,029
  • In genetics: 3,178
• Year to date:
  • Site-wide: 109,478
• Since beginning of last month:
  • Site-wide: None

All-optical electrophysiology in hiPSC-derived neurons with synthetic voltage sensors

• Downloaded 321 times
• Download rankings, all-time:
  • Site-wide: 76,703
  • In neuroscience: 11,854
• Year to date:
  • Site-wide: 2,596
• Since beginning of last month:
  • Site-wide: 13,184

Improved prediction of schizophrenia by leveraging genetic overlap with brain morphology

• Downloaded 302 times
• Download rankings, all-time:
  • Site-wide: 80,496
  • In psychiatry and clinical psychology: 250
• Year to date:
  • Site-wide: 36,929
• Since beginning of last month:
  • Site-wide: 34,118

Genome-Wide Association Identifies the First Risk Loci for Psychosis in Alzheimer Disease

• Downloaded 250 times
• Download rankings, all-time:
  • Site-wide: 91,570
  • In psychiatry and clinical psychology: 320
• Year to date:
  • Site-wide: 45,460
• Since beginning of last month:
  • Site-wide: 37,624

Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank

• Downloaded 241 times
• Download rankings, all-time:
  • Site-wide: 93,308
  • In genetic and genomic medicine: 332
• Year to date:
  • Site-wide: 32,083
• Since beginning of last month:
  • Site-wide: 72,376

Cannabis use is associated with increased levels of soluble gp130 in schizophrenia but not in bipolar disorder

• Downloaded 180 times
• Download rankings, all-time:
  • Site-wide: 106,637
  • In pharmacology and toxicology: 816
• Year to date:
  • Site-wide: 117,537
• Since beginning of last month:
  • Site-wide: 91,623

A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia

• Downloaded 166 times
• Download rankings, all-time:
  • Site-wide: 109,375
  • In neuroscience: 17,049
• Year to date:
  • Site-wide: 25,713
• Since beginning of last month:
  • Site-wide: 38,838

Cardiometabolic risk factors associated with brain age and accelerate brain ageing

• Downloaded 106 times
• Download rankings, all-time:
  • Site-wide: 120,935
  • In neurology: 502
• Year to date:
  • Site-wide: 11,908
• Since beginning of last month:
  • Site-wide: 4,056