Rxivist logo

Author: Patrick F Sullivan

Rankings

  • All-time downloads: 133,362 (rank: 220 out of 398,135)
  • Categories:
    • bioinformatics: 294 (rank: 26,223 (tie) out of 33,947)
    • ecology: 73 (rank: 16,521 (tie) out of 17,262)
    • genetics: 83,275 (rank: 22 out of 36,546)
    • genomics: 49,512 (rank: 131 out of 42,280)
    • systems biology: 208 (rank: 10,314 (tie) out of 11,646)

Downloads per author, site-wide

Preprints

Analysis of protein-coding genetic variation in 60,706 humans

genomics more details view paper
  • Downloaded 21,779 times
  • Download rankings, all-time:
    • Site-wide: 71 out of 93,322
    • In genomics: 10 out of 5,875
  • Year to date:
    • Site-wide: 17,719 out of 93,322
  • Since beginning of last month:
    • Site-wide: 19,292 out of 93,322

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

genetics more details view paper
  • Downloaded 10,281 times
  • Download rankings, all-time:
    • Site-wide: 240 out of 93,322
    • In genetics: 16 out of 4,774
  • Year to date:
    • Site-wide: 1,612 out of 93,322
  • Since beginning of last month:
    • Site-wide: 4,238 out of 93,322

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

genetics more details view paper
  • Downloaded 9,133 times
  • Download rankings, all-time:
    • Site-wide: 291 out of 93,322
    • In genetics: 22 out of 4,774
  • Year to date:
    • Site-wide: 13,236 out of 93,322
  • Since beginning of last month:
    • Site-wide: 9,975 out of 93,322

Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
  • Downloaded 6,970 times
  • Download rankings, all-time:
    • Site-wide: 451 out of 93,322
    • In genetics: 35 out of 4,774
  • Year to date:
    • Site-wide: 5,105 out of 93,322
  • Since beginning of last month:
    • Site-wide: 6,975 out of 93,322

Common risk variants identified in autism spectrum disorder

genetics more details view paper
  • Downloaded 6,669 times
  • Download rankings, all-time:
    • Site-wide: 486 out of 93,322
    • In genetics: 41 out of 4,774
  • Year to date:
    • Site-wide: 4,221 out of 93,322
  • Since beginning of last month:
    • Site-wide: 3,248 out of 93,322

Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimers disease risk

genetics more details view paper
  • Downloaded 4,990 times
  • Download rankings, all-time:
    • Site-wide: 794 out of 93,322
    • In genetics: 60 out of 4,774
  • Year to date:
    • Site-wide: 13,306 out of 93,322
  • Since beginning of last month:
    • Site-wide: 18,672 out of 93,322

Genome-wide Analysis of Insomnia (N=1,331,010) Identifies Novel Loci and Functional Pathways

genetics more details view paper
  • Downloaded 4,934 times
  • Download rankings, all-time:
    • Site-wide: 812 out of 93,322
    • In genetics: 61 out of 4,774
  • Year to date:
    • Site-wide: 10,405 out of 93,322
  • Since beginning of last month:
    • Site-wide: 12,001 out of 93,322

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

genetics more details view paper
  • Downloaded 4,908 times
  • Download rankings, all-time:
    • Site-wide: 823 out of 93,322
    • In genetics: 62 out of 4,774
  • Year to date:
    • Site-wide: 12,857 out of 93,322
  • Since beginning of last month:
    • Site-wide: 7,546 out of 93,322

Regulatory variants explain much more heritability than coding variants across 11 common diseases

genetics more details view paper
  • Downloaded 4,396 times
  • Download rankings, all-time:
    • Site-wide: 990 out of 93,322
    • In genetics: 74 out of 4,774
  • Year to date:
    • Site-wide: 48,563 out of 93,322
  • Since beginning of last month:
    • Site-wide: 54,595 out of 93,322

Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

genomics more details view paper
  • Downloaded 4,345 times
  • Download rankings, all-time:
    • Site-wide: 1,014 out of 93,322
    • In genomics: 212 out of 5,875
  • Year to date:
    • Site-wide: 2,652 out of 93,322
  • Since beginning of last month:
    • Site-wide: 4,166 out of 93,322

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

genetics more details view paper
  • Downloaded 4,232 times
  • Download rankings, all-time:
    • Site-wide: 1,076 out of 93,322
    • In genetics: 82 out of 4,774
  • Year to date:
    • Site-wide: 8,657 out of 93,322
  • Since beginning of last month:
    • Site-wide: 9,229 out of 93,322

Genetic Identification of Cell Types Underlying Brain Complex Traits Yields Novel Insights Into the Etiology of Parkinson’s Disease

genomics more details view paper
  • Downloaded 3,723 times
  • Download rankings, all-time:
    • Site-wide: 1,334 out of 93,322
    • In genomics: 279 out of 5,875
  • Year to date:
    • Site-wide: 1,526 out of 93,322
  • Since beginning of last month:
    • Site-wide: 7,266 out of 93,322

Genetic Identification Of Brain Cell Types Underlying Schizophrenia

genomics more details view paper
  • Downloaded 3,509 times
  • Download rankings, all-time:
    • Site-wide: 1,470 out of 93,322
    • In genomics: 308 out of 5,875
  • Year to date:
    • Site-wide: 33,115 out of 93,322
  • Since beginning of last month:
    • Site-wide: 52,719 out of 93,322

Psychiatric Genomics: An Update and an Agenda

genetics more details view paper
  • Downloaded 3,265 times
  • Download rankings, all-time:
    • Site-wide: 1,671 out of 93,322
    • In genetics: 120 out of 4,774
  • Year to date:
    • Site-wide: 32,648 out of 93,322
  • Since beginning of last month:
    • Site-wide: 23,357 out of 93,322

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

genomics more details view paper
  • Downloaded 2,519 times
  • Download rankings, all-time:
    • Site-wide: 2,611 out of 93,322
    • In genomics: 488 out of 5,875
  • Year to date:
    • Site-wide: 63,922 out of 93,322
  • Since beginning of last month:
    • Site-wide: 45,358 out of 93,322

Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

genetics more details view paper
  • Downloaded 2,447 times
  • Download rankings, all-time:
    • Site-wide: 2,734 out of 93,322
    • In genetics: 208 out of 4,774
  • Year to date:
    • Site-wide: 34,513 out of 93,322
  • Since beginning of last month:
    • Site-wide: 27,311 out of 93,322

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

genetics more details view paper
  • Downloaded 2,253 times
  • Download rankings, all-time:
    • Site-wide: 3,147 out of 93,322
    • In genetics: 240 out of 4,774
  • Year to date:
    • Site-wide: 78,283 out of 93,322
  • Since beginning of last month:
    • Site-wide: 64,119 out of 93,322

Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

genetics more details view paper
  • Downloaded 2,152 times
  • Download rankings, all-time:
    • Site-wide: 3,398 out of 93,322
    • In genetics: 254 out of 4,774
  • Year to date:
    • Site-wide: 12,939 out of 93,322
  • Since beginning of last month:
    • Site-wide: 7,542 out of 93,322

GWAS Meta-Analysis of Neuroticism (N=449,484) Identifies Novel Genetic Loci and Pathways

genetics more details view paper
  • Downloaded 2,098 times
  • Download rankings, all-time:
    • Site-wide: 3,544 out of 93,322
    • In genetics: 267 out of 4,774
  • Year to date:
    • Site-wide: 36,891 out of 93,322
  • Since beginning of last month:
    • Site-wide: 21,252 out of 93,322

Comparative genetic architectures of schizophrenia in East Asian and European populations

genetics more details view paper
  • Downloaded 2,005 times
  • Download rankings, all-time:
    • Site-wide: 3,803 out of 93,322
    • In genetics: 284 out of 4,774
  • Year to date:
    • Site-wide: 9,038 out of 93,322
  • Since beginning of last month:
    • Site-wide: 8,628 out of 93,322

Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia

genomics more details view paper
  • Downloaded 1,877 times
  • Download rankings, all-time:
    • Site-wide: 4,235 out of 93,322
    • In genomics: 718 out of 5,875
  • Year to date:
    • Site-wide: 59,007 out of 93,322
  • Since beginning of last month:
    • Site-wide: 39,176 out of 93,322

Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

genomics more details view paper
  • Downloaded 1,811 times
  • Download rankings, all-time:
    • Site-wide: 4,519 out of 93,322
    • In genomics: 756 out of 5,875
  • Year to date:
    • Site-wide: 8,620 out of 93,322
  • Since beginning of last month:
    • Site-wide: 18,826 out of 93,322

Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits

genetics more details view paper
  • Downloaded 1,716 times
  • Download rankings, all-time:
    • Site-wide: 4,908 out of 93,322
    • In genetics: 359 out of 4,774
  • Year to date:
    • Site-wide: 6,269 out of 93,322
  • Since beginning of last month:
    • Site-wide: 9,600 out of 93,322

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

genetics more details view paper
  • Downloaded 1,692 times
  • Download rankings, all-time:
    • Site-wide: 5,030 out of 93,322
    • In genetics: 368 out of 4,774
  • Year to date:
    • Site-wide: 63,458 out of 93,322
  • Since beginning of last month:
    • Site-wide: 46,696 out of 93,322

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
  • Downloaded 1,394 times
  • Download rankings, all-time:
    • Site-wide: 6,965 out of 93,322
    • In genomics: 1,086 out of 5,875
  • Year to date:
    • Site-wide: 59,109 out of 93,322
  • Since beginning of last month:
    • Site-wide: 40,523 out of 93,322

Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders

genomics more details view paper
  • Downloaded 1,376 times
  • Download rankings, all-time:
    • Site-wide: 7,101 out of 93,322
    • In genomics: 1,101 out of 5,875
  • Year to date:
    • Site-wide: 38,954 out of 93,322
  • Since beginning of last month:
    • Site-wide: 30,108 out of 93,322

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

genetics more details view paper
  • Downloaded 1,112 times
  • Download rankings, all-time:
    • Site-wide: 10,154 out of 93,322
    • In genetics: 685 out of 4,774
  • Year to date:
    • Site-wide: 5,334 out of 93,322
  • Since beginning of last month:
    • Site-wide: 5,582 out of 93,322

Evaluation Of Chromatin Accessibility In Prefrontal Cortex Of Schizophrenia Cases And Controls

genomics more details view paper
  • Downloaded 1,109 times
  • Download rankings, all-time:
    • Site-wide: 10,214 out of 93,322
    • In genomics: 1,470 out of 5,875
  • Year to date:
    • Site-wide: 63,128 out of 93,322
  • Since beginning of last month:
    • Site-wide: 52,729 out of 93,322

Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

genetics more details view paper
  • Downloaded 1,094 times
  • Download rankings, all-time:
    • Site-wide: 10,427 out of 93,322
    • In genetics: 706 out of 4,774
  • Year to date:
    • Site-wide: 25,812 out of 93,322
  • Since beginning of last month:
    • Site-wide: 46,445 out of 93,322

Gene expression imputation across multiple brain regions reveals schizophrenia risk throughout development.

genetics more details view paper
  • Downloaded 1,060 times
  • Download rankings, all-time:
    • Site-wide: 10,960 out of 93,322
    • In genetics: 738 out of 4,774
  • Year to date:
    • Site-wide: 42,854 out of 93,322
  • Since beginning of last month:
    • Site-wide: 46,240 out of 93,322

Functional consequences of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals

genomics more details view paper
  • Downloaded 978 times
  • Download rankings, all-time:
    • Site-wide: 12,479 out of 93,322
    • In genomics: 1,710 out of 5,875
  • Year to date:
    • Site-wide: 55,129 out of 93,322
  • Since beginning of last month:
    • Site-wide: 25,495 out of 93,322

Robust Hi-C chromatin loop maps in human neurogenesis and brain tissues at high-resolution

genomics more details view paper
  • Downloaded 976 times
  • Download rankings, all-time:
    • Site-wide: 12,518 out of 93,322
    • In genomics: 1,716 out of 5,875
  • Year to date:
    • Site-wide: 6,539 out of 93,322
  • Since beginning of last month:
    • Site-wide: 9,339 out of 93,322

Rare loss-of-function variants in KMT2F are associated with schizophrenia and developmental disorders

genomics more details view paper
  • Downloaded 972 times
  • Download rankings, all-time:
    • Site-wide: 12,604 out of 93,322
    • In genomics: 1,720 out of 5,875
  • Year to date:
    • Site-wide: 80,626 out of 93,322
  • Since beginning of last month:
    • Site-wide: 57,620 out of 93,322

Building a schizophrenia genetic network: Transcription Factor 4 regulates genes involved in neuronal development and schizophrenia risk.

genetics more details view paper
  • Downloaded 947 times
  • Download rankings, all-time:
    • Site-wide: 13,127 out of 93,322
    • In genetics: 870 out of 4,774
  • Year to date:
    • Site-wide: 43,257 out of 93,322
  • Since beginning of last month:
    • Site-wide: 17,278 out of 93,322

Common Variant Associations with Fragile X Syndrome

genetics more details view paper
  • Downloaded 925 times
  • Download rankings, all-time:
    • Site-wide: 13,618 out of 93,322
    • In genetics: 896 out of 4,774
  • Year to date:
    • Site-wide: 47,471 out of 93,322
  • Since beginning of last month:
    • Site-wide: 43,162 out of 93,322

Functional partitioning of local and distal gene expression regulation in multiple human tissues

genomics more details view paper
  • Downloaded 826 times
  • Download rankings, all-time:
    • Site-wide: 16,277 out of 93,322
    • In genomics: 2,051 out of 5,875
  • Year to date:
    • Site-wide: 83,956 out of 93,322
  • Since beginning of last month:
    • Site-wide: 88,843 out of 93,322

HUGIn: Hi-C Unifying Genomic Interrogator

genetics more details view paper
  • Downloaded 697 times
  • Download rankings, all-time:
    • Site-wide: 20,988 out of 93,322
    • In genetics: 1,326 out of 4,774
  • Year to date:
    • Site-wide: 88,279 out of 93,322
  • Since beginning of last month:
    • Site-wide: 69,261 out of 93,322

Reproducible Risk Loci and Psychiatric Comorbidities in Anxiety: Results from ~200,000 Million Veteran Program Participants

genetics more details view paper
  • Downloaded 689 times
  • Download rankings, all-time:
    • Site-wide: 21,354 out of 93,322
    • In genetics: 1,348 out of 4,774
  • Year to date:
    • Site-wide: 17,423 out of 93,322
  • Since beginning of last month:
    • Site-wide: 35,268 out of 93,322

Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

genetics more details view paper
  • Downloaded 681 times
  • Download rankings, all-time:
    • Site-wide: 21,767 out of 93,322
    • In genetics: 1,378 out of 4,774
  • Year to date:
    • Site-wide: 59,006 out of 93,322
  • Since beginning of last month:
    • Site-wide: 84,563 out of 93,322

Integrative analysis of rare variants and pathway information shows convergent results between immune pathways, drug targets and epilepsy genes

genomics more details view paper
  • Downloaded 665 times
  • Download rankings, all-time:
    • Site-wide: 22,533 out of 93,322
    • In genomics: 2,535 out of 5,875
  • Year to date:
    • Site-wide: 41,918 out of 93,322
  • Since beginning of last month:
    • Site-wide: 57,550 out of 93,322

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

genetics more details view paper
  • Downloaded 645 times
  • Download rankings, all-time:
    • Site-wide: 23,525 out of 93,322
    • In genetics: 1,459 out of 4,774
  • Year to date:
    • Site-wide: 55,314 out of 93,322
  • Since beginning of last month:
    • Site-wide: 50,003 out of 93,322

Proof of concept: Molecular prediction of schizophrenia risk

genomics more details view paper
  • Downloaded 582 times
  • Download rankings, all-time:
    • Site-wide: 27,100 out of 93,322
    • In genomics: 2,877 out of 5,875
  • Year to date:
    • Site-wide: 72,715 out of 93,322
  • Since beginning of last month:
    • Site-wide: 67,270 out of 93,322

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

genetics more details view paper
  • Downloaded 481 times
  • Download rankings, all-time:
    • Site-wide: 34,467 out of 93,322
    • In genetics: 2,021 out of 4,774
  • Year to date:
    • Site-wide: 20,248 out of 93,322
  • Since beginning of last month:
    • Site-wide: 32,019 out of 93,322

Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia.

genomics more details view paper
  • Downloaded 420 times
  • Download rankings, all-time:
    • Site-wide: 40,287 out of 93,322
    • In genomics: 3,719 out of 5,875
  • Year to date:
    • Site-wide: 6,564 out of 93,322
  • Since beginning of last month:
    • Site-wide: 11,334 out of 93,322

Characterization of single gene copy number variants in schizophrenia

genetics more details view paper
  • Downloaded 416 times
  • Download rankings, all-time:
    • Site-wide: 40,712 out of 93,322
    • In genetics: 2,375 out of 4,774
  • Year to date:
    • Site-wide: 59,340 out of 93,322
  • Since beginning of last month:
    • Site-wide: 43,604 out of 93,322

Genetic variation in the Major Histocompatibility Complex and association with depression

genetics more details view paper
  • Downloaded 387 times
  • Download rankings, all-time:
    • Site-wide: 43,886 out of 93,322
    • In genetics: 2,537 out of 4,774
  • Year to date:
    • Site-wide: 52,874 out of 93,322
  • Since beginning of last month:
    • Site-wide: 63,438 out of 93,322

Schizophrenia is characterized by age- and sex-specific effects on epigenetic aging

genomics more details view paper
  • Downloaded 369 times
  • Download rankings, all-time:
    • Site-wide: 46,102 out of 93,322
    • In genomics: 4,038 out of 5,875
  • Year to date:
    • Site-wide: 39,702 out of 93,322
  • Since beginning of last month:
    • Site-wide: 78,408 out of 93,322

Association Tests Using Copy Number Profile Curves (CONCUR) Enhances Power in Rare Copy Number Variant Analysis

bioinformatics more details view paper
  • Downloaded 294 times
  • Download rankings, all-time:
    • Site-wide: 56,524 out of 93,322
    • In bioinformatics: 6,190 out of 8,742
  • Year to date:
    • Site-wide: 50,231 out of 93,322
  • Since beginning of last month:
    • Site-wide: 52,419 out of 93,322

mTADA: a framework for analyzing de novo mutations in multiple traits

genomics more details view paper
  • Downloaded 282 times
  • Download rankings, all-time:
    • Site-wide: 58,405 out of 93,322
    • In genomics: 4,617 out of 5,875
  • Year to date:
    • Site-wide: 57,037 out of 93,322
  • Since beginning of last month:
    • Site-wide: 52,995 out of 93,322

Antipsychotic behavioral phenotypes in the mouse Collaborative Cross recombinant inbred inter-crosses (RIX)

systems biology more details view paper
  • Downloaded 208 times
  • Download rankings, all-time:
    • Site-wide: 70,790 out of 93,322
    • In systems biology: 2,004 out of 2,382
  • Year to date:
    • Site-wide: 38,176 out of 93,322
  • Since beginning of last month:
    • Site-wide: 45,605 out of 93,322

Labile carbon limits late winter microbial activity near Arctic treeline

ecology more details view paper
  • Downloaded 73 times
  • Download rankings, all-time:
    • Site-wide: 88,801 out of 93,322
    • In ecology: 3,826 out of 4,114
  • Year to date:
    • Site-wide: 62,795 out of 93,322
  • Since beginning of last month:
    • Site-wide: 46,046 out of 93,322

PanLingua

Sign up for the Rxivist weekly newsletter! (Click here for more details.)


News