Author: Aashish Manglik

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Preprints

Test performance evaluation of SARS-CoV-2 serological assays

• Downloaded 37,465 times
• Download rankings, all-time:
  • Site-wide: 136
  • In infectious diseases: 55
• Year to date:
  • Site-wide: 363
• Since beginning of last month:
  • Site-wide: 460

An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation

• Downloaded 17,883 times
• Download rankings, all-time:
  • Site-wide: 334
  • In biochemistry: 2
• Year to date:
  • Site-wide: 1,029
• Since beginning of last month:
  • Site-wide: 799

Platform for rapid nanobody discovery in vitro

• Downloaded 6,019 times
• Download rankings, all-time:
  • Site-wide: 1,324
  • In biochemistry: 17
• Year to date:
  • Site-wide: 8,572
• Since beginning of last month:
  • Site-wide: 12,568

Accelerating Protein Design Using Autoregressive Generative Models

• Downloaded 3,289 times
• Download rankings, all-time:
  • Site-wide: 3,171
  • In systems biology: 51
• Year to date:
  • Site-wide: 4,086
• Since beginning of last month:
  • Site-wide: 4,784

Structure of human ferroportin bound to hepcidin reveals mechanisms of iron homeostasis

• Downloaded 1,488 times
• Download rankings, all-time:
  • Site-wide: 10,135
  • In biochemistry: 196
• Year to date:
  • Site-wide: 8,188
• Since beginning of last month:
  • Site-wide: 18,193

A genetically encoded biosensor reveals location bias of opioid drug action

• Downloaded 992 times
• Download rankings, all-time:
  • Site-wide: 18,698
  • In neuroscience: 2,442
• Year to date:
  • Site-wide: 52,896
• Since beginning of last month:
  • Site-wide: 59,204

Hedgehog pathway activation through conformational blockade of the Patched sterol conduit

• Downloaded 815 times
• Download rankings, all-time:
  • Site-wide: 24,776
  • In biophysics: 731
• Year to date:
  • Site-wide: 46,646
• Since beginning of last month:
  • Site-wide: 29,966

Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization

• Downloaded 790 times
• Download rankings, all-time:
  • Site-wide: 25,884
  • In microbiology: 1,515
• Year to date:
  • Site-wide: 13,464
• Since beginning of last month:
  • Site-wide: 13,229

Smoothened Transduces Hedgehog Signals via Activity-Dependent Sequestration of PKA Catalytic Subunits

• Downloaded 563 times
• Download rankings, all-time:
  • Site-wide: 40,570
  • In biochemistry: 1,025
• Year to date:
  • Site-wide: 26,505
• Since beginning of last month:
  • Site-wide: 33,843

Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells

• Downloaded 455 times
• Download rankings, all-time:
  • Site-wide: 52,138
  • In cell biology: 2,290
• Year to date:
  • Site-wide: 100,476
• Since beginning of last month:
  • Site-wide: 110,249

Universal PCR and antibody testing demonstrate little to no transmission of SARS-CoV-2 in a rural community

• Downloaded 362 times
• Download rankings, all-time:
  • Site-wide: 65,392
  • In infectious diseases: 2,637
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 55,217