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Author: Nicholas T. Seyfried

Rankings

  • All-time downloads: 14,350 (rank: 11,863 )
  • Categories:
    • biochemistry: 1,564 (rank: 2,453 (tie) )
    • cell biology: 67 (rank: 37,024 (tie) )
    • genetics: 1,097 (rank: 14,293 (tie) )
    • genomics: 2,268 (rank: 10,128 (tie) )
    • neuroscience: 5,571 (rank: 2,898 )
    • systems biology: 3,783 (rank: 856 (tie) )

Downloads per author, site-wide

Preprints

A Consensus Proteomic Analysis of Alzheimer’s Disease Brain and Cerebrospinal Fluid Reveals Early Changes in Energy Metabolism Associated with Microglia and Astrocyte Activation

systems biology more details view paper
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    • In systems biology: 113
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    • Site-wide: 15,363

Integrated Proteomics Reveals Brain-Based Cerebrospinal Fluid Biomarkers in Asymptomatic and Symptomatic Alzheimer’s Disease

systems biology more details view paper
  • Downloaded 1,681 times
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    • Site-wide: 9,127
    • In systems biology: 178
  • Year to date:
    • Site-wide: 24,665
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    • Site-wide: None

Multiscale causal network models of Alzheimer's disease identify VGF as a key regulator of disease

genomics more details view paper
  • Downloaded 1,495 times
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    • Site-wide: 10,797
    • In genomics: 1,197
  • Year to date:
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Genetic control of the human brain proteome

genetics more details view paper
  • Downloaded 1,097 times
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    • In genetics: 874
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RNA-binding proteins with mixed charge domains self-assemble and aggregate in Alzheimer's Disease

biochemistry more details view paper
  • Downloaded 869 times
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    • Site-wide: 24,147
    • In biochemistry: 560
  • Year to date:
    • Site-wide: 110,216
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Microglial ERK signaling is a critical regulator of pro-inflammatory immune responses in Alzheimer’s disease

neuroscience more details view paper
  • Downloaded 761 times
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    • Site-wide: 29,041
    • In neuroscience: 3,964
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    • Site-wide: 19,461
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Tau-mediated Disruption of the Spliceosome Triggers Cryptic RNA-splicing and Neurodegeneration in Alzheimer's Disease

neuroscience more details view paper
  • Downloaded 745 times
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    • Site-wide: 29,926
    • In neuroscience: 4,124
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    • Site-wide: 74,630
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    • Site-wide: 53,659

Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior

neuroscience more details view paper
  • Downloaded 654 times
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    • Site-wide: 35,736
    • In neuroscience: 5,075
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Identification of conserved proteomic networks in neurodegenerative dementia

neuroscience more details view paper
  • Downloaded 649 times
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    • Site-wide: 36,136
    • In neuroscience: 5,123
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Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease

neuroscience more details view paper
  • Downloaded 551 times
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    • Site-wide: 44,476
    • In neuroscience: 6,497
  • Year to date:
    • Site-wide: 35,296
  • Since beginning of last month:
    • Site-wide: 33,176

Integrated analysis of the aging brain transcriptome and proteome in tauopathy

genomics more details view paper
  • Downloaded 514 times
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    • Site-wide: 48,144
    • In genomics: 3,851
  • Year to date:
    • Site-wide: 48,560
  • Since beginning of last month:
    • Site-wide: 49,555

Large-scale proteomic analysis of human prefrontal cortex identifies proteins associated with cognitive trajectory in advanced age

neuroscience more details view paper
  • Downloaded 452 times
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    • Site-wide: 55,746
    • In neuroscience: 8,404
  • Year to date:
    • Site-wide: 102,563
  • Since beginning of last month:
    • Site-wide: 73,845

Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease

neuroscience more details view paper
  • Downloaded 406 times
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    • Site-wide: 62,264
    • In neuroscience: 9,518
  • Year to date:
    • Site-wide: 30,020
  • Since beginning of last month:
    • Site-wide: 27,841

TBK1 interacts with tau and enhances neurodegeneration in tauopathy

neuroscience more details view paper
  • Downloaded 379 times
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    • Site-wide: 66,473
    • In neuroscience: 10,195
  • Year to date:
    • Site-wide: None
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Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calmodulin (CaM) Effector in Mouse Brain

biochemistry more details view paper
  • Downloaded 375 times
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    • Site-wide: 67,214
    • In biochemistry: 1,840
  • Year to date:
    • Site-wide: 118,559
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    • Site-wide: 99,255

Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus that are Necessary for Synapse Function

neuroscience more details view paper
  • Downloaded 345 times
  • Download rankings, all-time:
    • Site-wide: 72,193
    • In neuroscience: 11,135
  • Year to date:
    • Site-wide: 63,902
  • Since beginning of last month:
    • Site-wide: 68,811

Cerebral atherosclerosis contributes to Alzheimer's dementia independently of its hallmark amyloid and tau pathologies

neuroscience more details view paper
  • Downloaded 331 times
  • Download rankings, all-time:
    • Site-wide: 74,748
    • In neuroscience: 11,535
  • Year to date:
    • Site-wide: 90,605
  • Since beginning of last month:
    • Site-wide: 89,464

Middle-down proteomics reveals dense sites of methylation and phosphorylation in arginine-rich RNA-binding proteins

biochemistry more details view paper
  • Downloaded 320 times
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    • Site-wide: 76,885
    • In biochemistry: 2,174
  • Year to date:
    • Site-wide: 85,424
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Broad kinase inhibition mitigates early neuronal dysfunction and cognitive deficits in tauopathy

neuroscience more details view paper
  • Downloaded 298 times
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    • Site-wide: 81,074
    • In neuroscience: 12,590
  • Year to date:
    • Site-wide: 64,266
  • Since beginning of last month:
    • Site-wide: 73,077

Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia

genomics more details view paper
  • Downloaded 259 times
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    • Site-wide: 89,370
    • In genomics: 5,611
  • Year to date:
    • Site-wide: 86,391
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    • Site-wide: None

Mitochondrial energy dysfunction induces remodeling of the cardiac mitochondrial protein acylome

cell biology more details view paper
  • Downloaded 67 times
  • Download rankings, all-time:
    • Site-wide: 126,015
    • In cell biology: 5,780
  • Year to date:
    • Site-wide: 19,797
  • Since beginning of last month:
    • Site-wide: 6,497

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