Author: Steven A. McCarroll

Downloads per author, site-wide

Preprints

A Single-Cell Atlas of Cell Types, States, and Other Transcriptional Patterns from Nine Regions of the Adult Mouse Brain

• Downloaded 9,753 times
• Download rankings, all-time:
  • Site-wide: 274 out of 94,912
  • In neuroscience: 29 out of 16,862
• Year to date:
  • Site-wide: 3,424 out of 94,912
• Since beginning of last month:
  • Site-wide: 6,060 out of 94,912

Regulatory variants explain much more heritability than coding variants across 11 common diseases

• Downloaded 4,399 times
• Download rankings, all-time:
  • Site-wide: 1,012 out of 94,912
  • In genetics: 74 out of 4,824
• Year to date:
  • Site-wide: 49,855 out of 94,912
• Since beginning of last month:
  • Site-wide: 57,754 out of 94,912

Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse

• Downloaded 2,712 times
• Download rankings, all-time:
  • Site-wide: 2,348 out of 94,912
  • In neuroscience: 317 out of 16,862
• Year to date:
  • Site-wide: 474 out of 94,912
• Since beginning of last month:
  • Site-wide: 1,051 out of 94,912

Innovations in Primate Interneuron Repertoire

• Downloaded 2,458 times
• Download rankings, all-time:
  • Site-wide: 2,759 out of 94,912
  • In neuroscience: 378 out of 16,862
• Year to date:
  • Site-wide: 2,409 out of 94,912
• Since beginning of last month:
  • Site-wide: 2,468 out of 94,912

Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

• Downloaded 2,447 times
• Download rankings, all-time:
  • Site-wide: 2,790 out of 94,912
  • In genomics: 513 out of 5,955
• Year to date:
  • Site-wide: 49,652 out of 94,912
• Since beginning of last month:
  • Site-wide: 20,051 out of 94,912

Limited contribution of rare, noncoding variation to autism spectrum disorder from sequencing of 2,076 genomes in quartet families

• Downloaded 2,435 times
• Download rankings, all-time:
  • Site-wide: 2,820 out of 94,912
  • In genomics: 521 out of 5,955
• Year to date:
  • Site-wide: 56,964 out of 94,912
• Since beginning of last month:
  • Site-wide: 53,115 out of 94,912

Phenotypic landscape of schizophrenia-associated genes defines candidates and their shared functions

• Downloaded 2,327 times
• Download rankings, all-time:
  • Site-wide: 3,028 out of 94,912
  • In genetics: 231 out of 4,824
• Year to date:
  • Site-wide: 13,997 out of 94,912
• Since beginning of last month:
  • Site-wide: 22,041 out of 94,912

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

• Downloaded 2,255 times
• Download rankings, all-time:
  • Site-wide: 3,183 out of 94,912
  • In genetics: 240 out of 4,824
• Year to date:
  • Site-wide: 79,810 out of 94,912
• Since beginning of last month:
  • Site-wide: 68,970 out of 94,912

Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals

• Downloaded 1,868 times
• Download rankings, all-time:
  • Site-wide: 4,352 out of 94,912
  • In genetics: 316 out of 4,824
• Year to date:
  • Site-wide: 12,423 out of 94,912
• Since beginning of last month:
  • Site-wide: 20,819 out of 94,912

Insights about variation in meiosis from 31,228 human sperm genomes

• Downloaded 1,756 times
• Download rankings, all-time:
  • Site-wide: 4,825 out of 94,912
  • In genomics: 793 out of 5,955
• Year to date:
  • Site-wide: 8,555 out of 94,912
• Since beginning of last month:
  • Site-wide: 10,208 out of 94,912

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

• Downloaded 1,692 times
• Download rankings, all-time:
  • Site-wide: 5,118 out of 94,912
  • In genetics: 371 out of 4,824
• Year to date:
  • Site-wide: 66,732 out of 94,912
• Since beginning of last month:
  • Site-wide: 61,113 out of 94,912

Whole Genome Sequencing in Psychiatric Disorders: the WGSPD Consortium

• Downloaded 1,589 times
• Download rankings, all-time:
  • Site-wide: 5,700 out of 94,912
  • In genomics: 926 out of 5,955
• Year to date:
  • Site-wide: 22,440 out of 94,912
• Since beginning of last month:
  • Site-wide: 31,959 out of 94,912

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,398 times
• Download rankings, all-time:
  • Site-wide: 7,048 out of 94,912
  • In genomics: 1,097 out of 5,955
• Year to date:
  • Site-wide: 59,888 out of 94,912
• Since beginning of last month:
  • Site-wide: 44,743 out of 94,912

Monogenic and polygenic inheritance become instruments for clonal selection

• Downloaded 1,384 times
• Download rankings, all-time:
  • Site-wide: 7,158 out of 94,912
  • In genetics: 506 out of 4,824
• Year to date:
  • Site-wide: 7,203 out of 94,912
• Since beginning of last month:
  • Site-wide: 14,746 out of 94,912

Genetic predisposition to mosaic Y chromosome loss in blood is associated with genomic instability in other tissues and susceptibility to non-haematological cancers

• Downloaded 1,265 times
• Download rankings, all-time:
  • Site-wide: 8,347 out of 94,912
  • In genetics: 576 out of 4,824
• Year to date:
  • Site-wide: 31,445 out of 94,912
• Since beginning of last month:
  • Site-wide: 48,441 out of 94,912

Complement component 4 genes contribute sex-specific vulnerability in diverse illnesses

• Downloaded 1,081 times
• Download rankings, all-time:
  • Site-wide: 10,828 out of 94,912
  • In genetics: 726 out of 4,824
• Year to date:
  • Site-wide: 5,551 out of 94,912
• Since beginning of last month:
  • Site-wide: 7,634 out of 94,912

The Genetic Landscape of Diamond-Blackfan Anemia

• Downloaded 1,066 times
• Download rankings, all-time:
  • Site-wide: 11,085 out of 94,912
  • In genetics: 741 out of 4,824
• Year to date:
  • Site-wide: 48,667 out of 94,912
• Since beginning of last month:
  • Site-wide: 47,751 out of 94,912

Mapping genetic effects on cellular phenotypes with "cell villages"

• Downloaded 992 times
• Download rankings, all-time:
  • Site-wide: 12,424 out of 94,912
  • In genetics: 823 out of 4,824
• Year to date:
  • Site-wide: 1,957 out of 94,912
• Since beginning of last month:
  • Site-wide: 646 out of 94,912

Schizophrenia risk conferred by protein-coding de novo mutations

• Downloaded 775 times
• Download rankings, all-time:
  • Site-wide: 18,297 out of 94,912
  • In genetics: 1,154 out of 4,824
• Year to date:
  • Site-wide: 34,571 out of 94,912
• Since beginning of last month:
  • Site-wide: 48,319 out of 94,912

Higher genetic risk of schizophrenia is associated with lower cognitive performance in healthy individuals

• Downloaded 695 times
• Download rankings, all-time:
  • Site-wide: 21,449 out of 94,912
  • In genetics: 1,350 out of 4,824
• Year to date:
  • Site-wide: 81,417 out of 94,912
• Since beginning of last month:
  • Site-wide: 92,753 out of 94,912

The genomic landscape of clonal hematopoiesis in Japan

• Downloaded 539 times
• Download rankings, all-time:
  • Site-wide: 30,433 out of 94,912
  • In genetics: 1,815 out of 4,824
• Year to date:
  • Site-wide: 22,223 out of 94,912
• Since beginning of last month:
  • Site-wide: 26,985 out of 94,912

Contribution of rare copy number variants to bipolar disorder risk is limited to schizoaffective cases

• Downloaded 471 times
• Download rankings, all-time:
  • Site-wide: 36,008 out of 94,912
  • In genetics: 2,091 out of 4,824
• Year to date:
  • Site-wide: 48,619 out of 94,912
• Since beginning of last month:
  • Site-wide: 56,516 out of 94,912

Insights into dispersed duplications and complex structural mutations from whole genome sequencing 706 families

• Downloaded 282 times
• Download rankings, all-time:
  • Site-wide: 59,175 out of 94,912
  • In genomics: 4,669 out of 5,955
• Year to date:
  • Site-wide: 13,085 out of 94,912
• Since beginning of last month:
  • Site-wide: 1,440 out of 94,912