Author: Valentina Escott-Price

Downloads per author, site-wide

Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

• Downloaded 9,045 times
• Download rankings, all-time:
  • Site-wide: 265 out of 83,960
  • In genetics: 19 out of 4,413
• Year to date:
  • Site-wide: 13,230 out of 83,960
• Since beginning of last month:
  • Site-wide: 15,898 out of 83,960

Genomewide association study identifies 30 loci associated with bipolar disorder

• Downloaded 6,838 times
• Download rankings, all-time:
  • Site-wide: 406 out of 83,960
  • In genetics: 33 out of 4,413
• Year to date:
  • Site-wide: 4,348 out of 83,960
• Since beginning of last month:
  • Site-wide: 4,470 out of 83,960

Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

• Downloaded 2,404 times
• Download rankings, all-time:
  • Site-wide: 2,481 out of 83,960
  • In genomics: 478 out of 5,420
• Year to date:
  • Site-wide: 52,317 out of 83,960
• Since beginning of last month:
  • Site-wide: 54,796 out of 83,960

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

• Downloaded 1,690 times
• Download rankings, all-time:
  • Site-wide: 4,452 out of 83,960
  • In neuroscience: 663 out of 14,951
• Year to date:
  • Site-wide: 26,380 out of 83,960
• Since beginning of last month:
  • Site-wide: 23,503 out of 83,960

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

• Downloaded 1,675 times
• Download rankings, all-time:
  • Site-wide: 4,525 out of 83,960
  • In genetics: 339 out of 4,413
• Year to date:
  • Site-wide: 54,375 out of 83,960
• Since beginning of last month:
  • Site-wide: 50,421 out of 83,960

Genetic variability in response to Aβ deposition influences Alzheimer's risk

• Downloaded 1,484 times
• Download rankings, all-time:
  • Site-wide: 5,536 out of 83,960
  • In neuroscience: 826 out of 14,951
• Year to date:
  • Site-wide: 12,671 out of 83,960
• Since beginning of last month:
  • Site-wide: 14,236 out of 83,960

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,371 times
• Download rankings, all-time:
  • Site-wide: 6,343 out of 83,960
  • In genomics: 1,021 out of 5,420
• Year to date:
  • Site-wide: 54,193 out of 83,960
• Since beginning of last month:
  • Site-wide: 57,118 out of 83,960

Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety disorder and schizophrenia.

• Downloaded 1,085 times
• Download rankings, all-time:
  • Site-wide: 9,318 out of 83,960
  • In neuroscience: 1,467 out of 14,951
• Year to date:
  • Site-wide: 52,165 out of 83,960
• Since beginning of last month:
  • Site-wide: 57,123 out of 83,960

Medical consequences of pathogenic CNVs in adults: Analysis of the UK Biobank

• Downloaded 968 times
• Download rankings, all-time:
  • Site-wide: 11,222 out of 83,960
  • In genomics: 1,595 out of 5,420
• Year to date:
  • Site-wide: 20,117 out of 83,960
• Since beginning of last month:
  • Site-wide: 8,200 out of 83,960

Genome-wide analysis of risk-taking behaviour and cross-disorder genetic correlations in 116,255 individuals from the UK Biobank cohort

• Downloaded 771 times
• Download rankings, all-time:
  • Site-wide: 15,920 out of 83,960
  • In genetics: 1,038 out of 4,413
• Year to date:
  • Site-wide: 48,868 out of 83,960
• Since beginning of last month:
  • Site-wide: 47,077 out of 83,960

Genetic association study of psychotic experiences in UK Biobank

• Downloaded 666 times
• Download rankings, all-time:
  • Site-wide: 19,819 out of 83,960
  • In genetics: 1,268 out of 4,413
• Year to date:
  • Site-wide: 30,292 out of 83,960
• Since beginning of last month:
  • Site-wide: 29,672 out of 83,960

Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia

• Downloaded 637 times
• Download rankings, all-time:
  • Site-wide: 21,153 out of 83,960
  • In genetics: 1,347 out of 4,413
• Year to date:
  • Site-wide: 48,500 out of 83,960
• Since beginning of last month:
  • Site-wide: 39,470 out of 83,960

The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function

• Downloaded 633 times
• Download rankings, all-time:
  • Site-wide: 21,349 out of 83,960
  • In genetics: 1,359 out of 4,413
• Year to date:
  • Site-wide: 28,168 out of 83,960
• Since beginning of last month:
  • Site-wide: 26,852 out of 83,960

Association between schizophrenia and both loss of function and missense mutations in paralog conserved sites of voltage-gated sodium channels

• Downloaded 629 times
• Download rankings, all-time:
  • Site-wide: 21,506 out of 83,960
  • In genetics: 1,369 out of 4,413
• Year to date:
  • Site-wide: 51,195 out of 83,960
• Since beginning of last month:
  • Site-wide: 42,738 out of 83,960

A Transcriptome Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia

• Downloaded 551 times
• Download rankings, all-time:
  • Site-wide: 25,798 out of 83,960
  • In genetics: 1,611 out of 4,413
• Year to date:
  • Site-wide: 40,566 out of 83,960
• Since beginning of last month:
  • Site-wide: 72,378 out of 83,960

Heritability and genetic variance of dementia with Lewy bodies

• Downloaded 550 times
• Download rankings, all-time:
  • Site-wide: 25,898 out of 83,960
  • In neuroscience: 4,378 out of 14,951
• Year to date:
  • Site-wide: 15,697 out of 83,960
• Since beginning of last month:
  • Site-wide: 7,492 out of 83,960

Gene based Analysis in HRC Imputed Genome Wide Association Data Identifies Three Novel Genes for Alzheimer's Disease

• Downloaded 445 times
• Download rankings, all-time:
  • Site-wide: 33,453 out of 83,960
  • In genetics: 2,006 out of 4,413
• Year to date:
  • Site-wide: 60,576 out of 83,960
• Since beginning of last month:
  • Site-wide: 65,428 out of 83,960

Analyses of rare and common alleles in parent-proband trios implicate rare missense variants in SLC6A1 in schizophrenia and confirm the involvement of loss of function intolerant and neurodevelopmental disorder genes.

• Downloaded 445 times
• Download rankings, all-time:
  • Site-wide: 33,480 out of 83,960
  • In genetics: 2,007 out of 4,413
• Year to date:
  • Site-wide: 35,206 out of 83,960
• Since beginning of last month:
  • Site-wide: 32,270 out of 83,960

Effects of pathogenic CNVs on physical traits in participants of the UK Biobank

• Downloaded 338 times
• Download rankings, all-time:
  • Site-wide: 44,623 out of 83,960
  • In genetics: 2,616 out of 4,413
• Year to date:
  • Site-wide: 66,134 out of 83,960
• Since beginning of last month:
  • Site-wide: 56,381 out of 83,960

Differences in Genetic Liability for Insomnia and Hypersomnia in Bipolar Disorder Subtypes

• Downloaded 298 times
• Download rankings, all-time:
  • Site-wide: 49,992 out of 83,960
  • In genomics: 4,161 out of 5,420
• Year to date:
  • Site-wide: 63,843 out of 83,960
• Since beginning of last month:
  • Site-wide: 53,152 out of 83,960

Positioning Personal Polygenic Risk score against the population background.

• Downloaded 282 times
• Download rankings, all-time:
  • Site-wide: 52,169 out of 83,960
  • In bioinformatics: 5,828 out of 8,046
• Year to date:
  • Site-wide: 21,807 out of 83,960
• Since beginning of last month:
  • Site-wide: 12,011 out of 83,960