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Author: Michael C O'Donovan

  • ORCiD: http://orcid.org/0000-0001-7073-2379
  • Most recently observed institution: MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK

Rankings

  • All-time downloads: 47,453 (rank: 2,798 )
  • Categories:
    • genetic and genomic medicine: 4,533 (rank: 125 )
    • genetics: 20,731 (rank: 444 )
    • genomics: 18,490 (rank: 569 )
    • neuroscience: 1,656 (rank: 12,712 (tie) )
    • pharmacology and therapeutics: 88 (rank: 718 (tie) )
    • psychiatry and clinical psychology: 1,955 (rank: 238 )

Downloads per author, site-wide

Preprints

Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
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    • Site-wide: 1,129
    • In genetics: 38
  • Year to date:
    • Site-wide: 16,029
  • Since beginning of last month:
    • Site-wide: 13,125

Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

genomics more details view paper
  • Downloaded 4,701 times
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    • Site-wide: 2,029
    • In genomics: 216
  • Year to date:
    • Site-wide: 12,703
  • Since beginning of last month:
    • Site-wide: 15,119

Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia

genetic and genomic medicine more details view paper
  • Downloaded 3,783 times
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    • Site-wide: 2,763
    • In genetic and genomic medicine: 8
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    • Site-wide: 610
  • Since beginning of last month:
    • Site-wide: 552

Genetic Identification Of Brain Cell Types Underlying Schizophrenia

genomics more details view paper
  • Downloaded 3,585 times
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    • Site-wide: 3,001
    • In genomics: 352
  • Year to date:
    • Site-wide: 67,261
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    • Site-wide: 55,017

Psychiatric Genomics: An Update and an Agenda

genetics more details view paper
  • Downloaded 3,345 times
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    • Site-wide: 3,317
    • In genetics: 134
  • Year to date:
    • Site-wide: 59,058
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Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

genomics more details view paper
  • Downloaded 2,563 times
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    • Site-wide: 4,835
    • In genomics: 563
  • Year to date:
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  • Since beginning of last month:
    • Site-wide: 86,611

Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

genomics more details view paper
  • Downloaded 2,496 times
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    • Site-wide: 5,053
    • In genomics: 591
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Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits

genetics more details view paper
  • Downloaded 2,175 times
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    • In genetics: 304
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Sex differences in gene expression in the human fetal brain

genomics more details view paper
  • Downloaded 1,700 times
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    • Site-wide: 8,926
    • In genomics: 1,003
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Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights

psychiatry and clinical psychology more details view paper
  • Downloaded 1,557 times
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    • Site-wide: 10,155
    • In psychiatry and clinical psychology: 32
  • Year to date:
    • Site-wide: 2,678
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    • Site-wide: 3,241

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
  • Downloaded 1,447 times
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    • Site-wide: 11,298
    • In genomics: 1,257
  • Year to date:
    • Site-wide: 59,275
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    • Site-wide: 55,050

A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

genetics more details view paper
  • Downloaded 1,396 times
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    • Site-wide: 11,926
    • In genetics: 602
  • Year to date:
    • Site-wide: 40,514
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    • Site-wide: 54,567

Genetic association study of psychotic experiences in UK Biobank

genetics more details view paper
  • Downloaded 780 times
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    • Site-wide: 27,950
    • In genetics: 1,392
  • Year to date:
    • Site-wide: 44,586
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    • Site-wide: 32,408

The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function

genetics more details view paper
  • Downloaded 777 times
  • Download rankings, all-time:
    • Site-wide: 28,131
    • In genetics: 1,400
  • Year to date:
    • Site-wide: 67,418
  • Since beginning of last month:
    • Site-wide: 78,131

Association between schizophrenia and both loss of function and missense mutations in paralog conserved sites of voltage-gated sodium channels

genetics more details view paper
  • Downloaded 735 times
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    • Site-wide: 30,396
    • In genetics: 1,506
  • Year to date:
    • Site-wide: 102,565
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    • Site-wide: 97,858

Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia

genetics more details view paper
  • Downloaded 732 times
  • Download rankings, all-time:
    • Site-wide: 30,583
    • In genetics: 1,515
  • Year to date:
    • Site-wide: 67,056
  • Since beginning of last month:
    • Site-wide: None

Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia.

genomics more details view paper
  • Downloaded 627 times
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    • Site-wide: 37,631
    • In genomics: 3,220
  • Year to date:
    • Site-wide: 25,451
  • Since beginning of last month:
    • Site-wide: 20,150

A Transcriptome Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia

genetics more details view paper
  • Downloaded 627 times
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    • Site-wide: 37,654
    • In genetics: 1,838
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    • Site-wide: 82,687
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    • Site-wide: 52,956

Synaptic protein DLG2 controls neurogenic transcriptional programs disrupted in schizophrenia and related disorders

genetics more details view paper
  • Downloaded 616 times
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    • Site-wide: 38,451
    • In genetics: 1,877
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    • Site-wide: 16,190
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Investigating the potential effect of antihypertensive medication on psychiatric disorders: a mendelian randomisation study

genetic and genomic medicine more details view paper
  • Downloaded 552 times
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    • Site-wide: 44,229
    • In genetic and genomic medicine: 124
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    • Site-wide: 23,229
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    • Site-wide: 18,511

Genetic association of FMRP targets with psychiatric disorders

neuroscience more details view paper
  • Downloaded 527 times
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    • Site-wide: 46,706
    • In neuroscience: 6,848
  • Year to date:
    • Site-wide: 37,856
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    • Site-wide: 24,191

The independent and combined influence of schizophrenia polygenic risk score and heavy cannabis use on risk for psychotic disorder: A case-control analysis from the EUGEI study.

genetics more details view paper
  • Downloaded 518 times
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    • Site-wide: 47,592
    • In genetics: 2,277
  • Year to date:
    • Site-wide: 36,320
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    • Site-wide: 28,005

Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations

genetics more details view paper
  • Downloaded 509 times
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    • Site-wide: 48,593
    • In genetics: 2,321
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    • Site-wide: 20,323
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    • Site-wide: 35,649

Dynamic expression of risk genes for schizophrenia and bipolar disorder across development

neuroscience more details view paper
  • Downloaded 473 times
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    • Site-wide: 52,895
    • In neuroscience: 7,911
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    • Site-wide: None
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The role of rare copy number variants in depression

neuroscience more details view paper
  • Downloaded 453 times
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    • Site-wide: 55,430
    • In neuroscience: 8,337
  • Year to date:
    • Site-wide: 51,899
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    • Site-wide: 79,357

Effects of pathogenic CNVs on physical traits in participants of the UK Biobank

genetics more details view paper
  • Downloaded 451 times
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    • Site-wide: 55,708
    • In genetics: 2,643
  • Year to date:
    • Site-wide: 40,918
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    • Site-wide: 37,975

Meta-analysis of Scandinavian Schizophrenia Exomes

genetics more details view paper
  • Downloaded 438 times
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    • Site-wide: 57,535
    • In genetics: 2,717
  • Year to date:
    • Site-wide: 40,199
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    • Site-wide: 42,958

Schizophrenia polygenic risk score and cannabis use modify psychosis expression in first episode psychosis patients and population controls

psychiatry and clinical psychology more details view paper
  • Downloaded 398 times
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    • Site-wide: 63,330
    • In psychiatry and clinical psychology: 189
  • Year to date:
    • Site-wide: 41,847
  • Since beginning of last month:
    • Site-wide: 40,178

Novel Insight into the Aetiology of Autism Spectrum Disorder Gained by Integrating Expression Data with Genome-wide Association Statistics

genomics more details view paper
  • Downloaded 392 times
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    • Site-wide: 64,319
    • In genomics: 4,633
  • Year to date:
    • Site-wide: 119,367
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    • Site-wide: 87,931

Identifying novel subtypes of irritability using a developmental genetic approach

genetics more details view paper
  • Downloaded 366 times
  • Download rankings, all-time:
    • Site-wide: 68,486
    • In genetics: 3,193
  • Year to date:
    • Site-wide: 105,013
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    • Site-wide: 93,299

Differences in Genetic Liability for Insomnia and Hypersomnia in Bipolar Disorder Subtypes

genomics more details view paper
  • Downloaded 356 times
  • Download rankings, all-time:
    • Site-wide: 70,194
    • In genomics: 4,891
  • Year to date:
    • Site-wide: 104,622
  • Since beginning of last month:
    • Site-wide: 80,099

The rate of de novo CNVs in healthy controls

genomics more details view paper
  • Downloaded 335 times
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    • Site-wide: 73,820
    • In genomics: 5,035
  • Year to date:
    • Site-wide: 87,508
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    • Site-wide: 86,838

Effects of pathogenic CNVs on biochemical markers: a study on the UK Biobank

genomics more details view paper
  • Downloaded 288 times
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    • Site-wide: 82,844
    • In genomics: 5,380
  • Year to date:
    • Site-wide: 64,387
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Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by mutation of the psychiatric risk gene Cacna1c

neuroscience more details view paper
  • Downloaded 203 times
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    • Site-wide: 101,169
    • In neuroscience: 15,817
  • Year to date:
    • Site-wide: 47,457
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    • Site-wide: 46,725

Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder

genetic and genomic medicine more details view paper
  • Downloaded 198 times
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    • Site-wide: 102,282
    • In genetic and genomic medicine: 396
  • Year to date:
    • Site-wide: 53,769
  • Since beginning of last month:
    • Site-wide: 48,400

Clozapine metabolism is associated with Absolute Neutrophil Count in individuals with treatment-resistant schizophrenia

pharmacology and therapeutics more details view paper
  • Downloaded 88 times
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    • Site-wide: 123,144
    • In pharmacology and therapeutics: 97
  • Year to date:
    • Site-wide: 13,671
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