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Author: Nevan J. Krogan

Rankings

  • All-time downloads: 205,153 (rank: 84 out of 426,983)
  • Categories:
    • biochemistry: 17,226 (rank: 61 out of 20,786)
    • bioinformatics: 1,033 (rank: 11,937 (tie) out of 36,205)
    • cancer biology: 1,216 (rank: 4,500 (tie) out of 30,504)
    • cell biology: 1,939 (rank: 2,276 out of 32,957)
    • developmental biology: 1,146 (rank: 2,435 (tie) out of 17,001)
    • evolutionary biology: 562 (rank: 10,040 (tie) out of 21,798)
    • genetics: 2,538 (rank: 6,663 (tie) out of 38,054)
    • microbiology: 6,514 (rank: 1,454 out of 50,831)
    • molecular biology: 1,024 (rank: 4,223 (tie) out of 23,456)
    • physiology: 367 (rank: 3,300 (tie) out of 9,562)
    • systems biology: 171,588 (rank: 2 out of 12,484)

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Preprints

The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity

molecular biology more details view paper

No bioRxiv download data for this paper yet.

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

systems biology more details view paper
  • Downloaded 168,470 times
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    • Site-wide: 6 out of 101,083
    • In systems biology: 1 out of 2,567
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    • Site-wide: 4 out of 101,083
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    • Site-wide: 29 out of 101,083

An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation

biochemistry more details view paper
  • Downloaded 16,647 times
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    • In biochemistry: 2 out of 3,450
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A CRISPR-Cas9 Genome Engineering Platform in Primary CD4+ T Cells for the Interrogation of HIV Host Factors

systems biology more details view paper
  • Downloaded 2,352 times
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    • In systems biology: 80 out of 2,567
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Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses

microbiology more details view paper
  • Downloaded 1,849 times
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    • In microbiology: 336 out of 8,973
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    • Site-wide: 1,024 out of 101,083
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    • Site-wide: 54 out of 101,083

BAF chromatin remodeling complex subunit diversity promotes temporally distinct gene expression programs in cardiogenes

developmental biology more details view paper
  • Downloaded 1,146 times
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    • In developmental biology: 221 out of 3,019
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Efficient Generation of Isogenic Primary Human Myeloid Cells using CRISPR-Cas9 Ribonucleoproteins

genetics more details view paper
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Adhesion-mediated mechanosignaling forces mitohormesis

cell biology more details view paper
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    • In cell biology: 452 out of 5,235
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    • Site-wide: 7,106 out of 101,083

SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Suppresses Antiviral Responses in Cells

bioinformatics more details view paper
  • Downloaded 1,033 times
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    • Site-wide: 12,708 out of 101,083
    • In bioinformatics: 1,990 out of 9,277
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    • Site-wide: 2,496 out of 101,083
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    • Site-wide: 512 out of 101,083

Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins

molecular biology more details view paper
  • Downloaded 1,024 times
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    • Site-wide: 12,903 out of 101,083
    • In molecular biology: 436 out of 3,509
  • Year to date:
    • Site-wide: 18,418 out of 101,083
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    • Site-wide: 27,761 out of 101,083

Delineation of the SUMO-Modified Proteome Reveals Regulatory Functions Throughout Meiosis

genetics more details view paper
  • Downloaded 949 times
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    • Site-wide: 14,592 out of 101,083
    • In genetics: 940 out of 5,030
  • Year to date:
    • Site-wide: 8,663 out of 101,083
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    • Site-wide: 15,175 out of 101,083

The cellular NMD pathway restricts Zika virus infection and is targeted by the viral capsid protein

microbiology more details view paper
  • Downloaded 882 times
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    • Site-wide: 16,362 out of 101,083
    • In microbiology: 1,068 out of 8,973
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    • Site-wide: 49,786 out of 101,083
  • Since beginning of last month:
    • Site-wide: 49,883 out of 101,083

An Mtb-Human Protein-Protein Interaction Map Reveals that Bacterial LpqN Antagonizes CBL, a Host Ubiquitin Ligase that Regulates the Balance Between Anti-Viral and Anti-Bacterial Responses

microbiology more details view paper
  • Downloaded 796 times
  • Download rankings, all-time:
    • Site-wide: 19,240 out of 101,083
    • In microbiology: 1,282 out of 8,973
  • Year to date:
    • Site-wide: 55,808 out of 101,083
  • Since beginning of last month:
    • Site-wide: 59,177 out of 101,083

Global proteomic profiling of primary macrophages during M. tuberculosis infection identifies TAX1BP1 as a mediator of autophagy targeting

microbiology more details view paper
  • Downloaded 781 times
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    • Site-wide: 19,839 out of 101,083
    • In microbiology: 1,329 out of 8,973
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    • Site-wide: 25,969 out of 101,083
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    • Site-wide: 25,412 out of 101,083

Biophysical basis of cellular multi-specificity encoded in a model molecular switch

systems biology more details view paper
  • Downloaded 766 times
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    • Site-wide: 20,366 out of 101,083
    • In systems biology: 545 out of 2,567
  • Year to date:
    • Site-wide: 3,929 out of 101,083
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    • Site-wide: 18,586 out of 101,083

Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling

microbiology more details view paper
  • Downloaded 732 times
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    • Site-wide: 21,727 out of 101,083
    • In microbiology: 1,464 out of 8,973
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    • Site-wide: 4,208 out of 101,083
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    • Site-wide: 16,122 out of 101,083

Two accessory proteins govern MmpL3 mycolic acid transport in mycobacteria

microbiology more details view paper
  • Downloaded 615 times
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    • Site-wide: 27,981 out of 101,083
    • In microbiology: 1,895 out of 8,973
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    • Site-wide: 48,350 out of 101,083
  • Since beginning of last month:
    • Site-wide: 32,361 out of 101,083

A tyrosine kinase protein interaction map reveals targetable EGFR network oncogenesis in lung cancer

cancer biology more details view paper
  • Downloaded 613 times
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    • Site-wide: 28,068 out of 101,083
    • In cancer biology: 890 out of 3,627
  • Year to date:
    • Site-wide: 5,530 out of 101,083
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    • Site-wide: 9,359 out of 101,083

Synthetic essentiality of metabolic regulator PDHK1 in PTEN-deficient cells and cancers

cancer biology more details view paper
  • Downloaded 603 times
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    • In cancer biology: 909 out of 3,627
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    • Site-wide: 49,800 out of 101,083
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    • Site-wide: 60,936 out of 101,083

Conservation and structural analysis of the Xenopus laevis phospho-proteome

evolutionary biology more details view paper
  • Downloaded 562 times
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    • Site-wide: 31,477 out of 101,083
    • In evolutionary biology: 2,012 out of 6,029
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    • Site-wide: 70,484 out of 101,083

Smoothened Transduces Hedgehog Signals via Activity-Dependent Sequestration of PKA Catalytic Subunits

biochemistry more details view paper
  • Downloaded 495 times
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    • Site-wide: 36,904 out of 101,083
    • In biochemistry: 1,076 out of 3,450
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    • Site-wide: 7,709 out of 101,083
  • Since beginning of last month:
    • Site-wide: 7,939 out of 101,083

Dynamic proteomics profiling of Legionella pneumophila infection unveils modulation of the host mitochondrial stress response pathway

cell biology more details view paper
  • Downloaded 466 times
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    • In cell biology: 1,960 out of 5,235
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    • Site-wide: 12,239 out of 101,083

Protein Moonlighting Revealed by Non-Catalytic Phenotypes of Yeast Enzymes

genetics more details view paper
  • Downloaded 393 times
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    • In genetics: 2,701 out of 5,030
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    • Site-wide: 67,957 out of 101,083

Chaperone-Mediated Reflux of Secretory Proteins to the Cytosol During Endoplasmic Reticulum Stress

cell biology more details view paper
  • Downloaded 383 times
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    • In cell biology: 2,490 out of 5,235
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    • Site-wide: 80,929 out of 101,083

Brown adipocyte NOSEMPE promotes nonmitochondrial thermogenesis and improves systemic metabolism through ATF4 activation

physiology more details view paper
  • Downloaded 367 times
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    • Site-wide: 51,348 out of 101,083
    • In physiology: 404 out of 1,442
  • Year to date:
    • Site-wide: 44,342 out of 101,083
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    • Site-wide: 46,871 out of 101,083

Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the viral Core

microbiology more details view paper
  • Downloaded 362 times
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    • Site-wide: 52,000 out of 101,083
    • In microbiology: 3,910 out of 8,973
  • Year to date:
    • Site-wide: 51,374 out of 101,083
  • Since beginning of last month:
    • Site-wide: 87,021 out of 101,083

Comparative analysis of macrophage post-translational modifications during intracellular bacterial pathogen infection

microbiology more details view paper
  • Downloaded 336 times
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    • Site-wide: 55,668 out of 101,083
    • In microbiology: 4,239 out of 8,973
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    • Site-wide: 14,090 out of 101,083
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    • Site-wide: 12,617 out of 101,083

Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection

microbiology more details view paper
  • Downloaded 161 times
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    • Site-wide: 85,411 out of 101,083
    • In microbiology: 7,148 out of 8,973
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    • Site-wide: 38,486 out of 101,083
  • Since beginning of last month:
    • Site-wide: 49,992 out of 101,083

The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae

genetics more details view paper
  • Downloaded 93 times
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    • Site-wide: 94,556 out of 101,083
    • In genetics: 4,815 out of 5,030
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    • Site-wide: 67,850 out of 101,083
  • Since beginning of last month:
    • Site-wide: 84,033 out of 101,083

Bimodal evolution of Src and Abl kinase substrate specificity revealed using mammalian cell extract as substrate pool

biochemistry more details view paper
  • Downloaded 84 times
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    • Site-wide: 95,546 out of 101,083
    • In biochemistry: 3,233 out of 3,450
  • Year to date:
    • Site-wide: 73,305 out of 101,083
  • Since beginning of last month:
    • Site-wide: 36,343 out of 101,083

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