Author: Roland Eils

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Preprints

The Human Cell Atlas

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SARS-CoV-2 receptor ACE2 and TMPRSS2 are predominantly expressed in a transient secretory cell type in subsegmental bronchial branches

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Single nucleus and in situ RNA sequencing reveals cell topographies in the human pancreas

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Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity

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A Comprehensive Assessment of Somatic Mutation Calling in Cancer Genomes

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Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments

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A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair

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The landscape of viral associations in human cancers

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pheno-seq - linking morphological features to gene expression in 3D cell culture systems

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Deciphering programs of transcriptional regulation by combined deconvolution of multiple omics layers

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Segmentation-free inference of cell-types from in situ transcriptomics data

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Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics

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Genomic footprints of activated telomere maintenance mechanisms in cancer

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ACEseq - allele specific copy number estimation from whole genome sequencing

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Framework For Quality Assessment Of Whole Genome, Cancer Sequences

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Resolving Drug Effects In Patient-Derived Cancer Cells Links Organoid Responses To Genome Alterations

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Gene set inference from single-cell sequencing data using a hybrid of matrix factorization and variational autoencoders

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Cell-specific CRISPR/Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins

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Web-based design and analysis tools for CRISPR base editing

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Identification and prioritisation of causal variants in human genetic disorders from exome or whole genome sequencing data

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Computational design of anti-CRISPR proteins with improved inhibition potency and expanded specificity

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Impact of cancer mutational signatures on transcription factor motifs in the human genome

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Single-fluorescent protein reporters allow parallel quantification of NK cell-mediated granzyme and caspase activities in single target cells

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Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein

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Automated screening by 3D light-sheet microscopy with high spatial and temporal resolution reveals mitotic phenotypes

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Unraveling mitotic protein networks by 3D multiplexed epitope drug screening

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HTSlib-js: Developer toolkit for a client-side JavaScript interface for HTSlib

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Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4

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Induced aneuploidy disrupts MCF10A acini formation and CCND1 expression

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