Author: Olli T. Raitakari

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Preprints

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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  • Site-wide: 3,750
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Integrative approaches for large-scale transcriptome-wide association studies

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Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

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The Polygenic and Monogenic Basis of Blood Traits and Diseases

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  • In genetic and genomic medicine: 20
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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 9,458
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New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

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  • In genomics: 1,109
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Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

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Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

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An epigenome-wide association study of educational attainment (n = 10,767)

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Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

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  • Site-wide: 20,302
  • In epidemiology: 1,171
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  • Site-wide: 71,169
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Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

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Genetic Association Study of Childhood Aggression across raters, instruments and age

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Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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  • In genomics: 2,726
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Genetic and environmental perturbations lead to regulatory decoherence

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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

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  • Site-wide: 39,714
  • In genetics: 1,923
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Metabolic Effects Of Risk Alleles In PNPLA3, TM6SF2, GCKR, And LYPLAL1 Inform About Heterogeneity Of Non-Alcoholic Fatty Liver Disease

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  • Site-wide: 40,438
  • In epidemiology: 1,903
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Discovering patterns of pleiotropy in genome-wide association studies

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  • Site-wide: 105,048
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Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

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  • Site-wide: 43,347
  • In genetics: 2,087
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Metabolic signatures of birth weight in 18288 adolescents and adults

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  • Site-wide: 45,273
  • In systems biology: 1,053
• Year to date:
  • Site-wide: 105,094
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Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

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  • In genomics: 3,931
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Meta-analysis of exome array data identifies six novel genetic loci for lung function

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  • Site-wide: 52,756
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Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns

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Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition

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  • Site-wide: 81,337

A genome-wide association study of total child psychiatric problems scores

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  • Site-wide: 85,066
  • In psychiatry and clinical psychology: 278
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  • Site-wide: 59,431

Maternal and fetal genetic contribution to gestational weight gain

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  • Site-wide: 98,866

Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles

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  • Site-wide: 90,958
  • In genetic and genomic medicine: 318
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  • Site-wide: 6,100

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

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  • Site-wide: 91,842
  • In genetics: 4,182
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Gene regulation contributes to explain the impact of early life socioeconomic disadvantage on adult inflammatory levels in two European cohort studies

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  • Site-wide: 50,162