Author: Terho Lehtimäki

Downloads per author, site-wide

Preprints

Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism

• Downloaded 10,138 times
• Download rankings, all-time:
  • Site-wide: 742
  • In genetics: 22
• Year to date:
  • Site-wide: 3,786
• Since beginning of last month:
  • Site-wide: 3,375

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

• Downloaded 9,365 times
• Download rankings, all-time:
  • Site-wide: 817
  • In genomics: 68
• Year to date:
  • Site-wide: 3,283
• Since beginning of last month:
  • Site-wide: None

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 3,247 times
• Download rankings, all-time:
  • Site-wide: 3,471
  • In genetics: 149
• Year to date:
  • Site-wide: 26,115
• Since beginning of last month:
  • Site-wide: 26,158

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

• Downloaded 3,069 times
• Download rankings, all-time:
  • Site-wide: 3,747
  • In genetics: 167
• Year to date:
  • Site-wide: 39,415
• Since beginning of last month:
  • Site-wide: 51,372

Integrative approaches for large-scale transcriptome-wide association studies

• Downloaded 2,879 times
• Download rankings, all-time:
  • Site-wide: 4,073
  • In genetics: 185
• Year to date:
  • Site-wide: 31,910
• Since beginning of last month:
  • Site-wide: 33,009

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

• Downloaded 2,502 times
• Download rankings, all-time:
  • Site-wide: 5,035
  • In genetics: 231
• Year to date:
  • Site-wide: 71,736
• Since beginning of last month:
  • Site-wide: 67,007

Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

• Downloaded 2,264 times
• Download rankings, all-time:
  • Site-wide: 5,836
  • In genetics: 279
• Year to date:
  • Site-wide: 4,386
• Since beginning of last month:
  • Site-wide: 2,861

The Polygenic and Monogenic Basis of Blood Traits and Diseases

• Downloaded 1,949 times
• Download rankings, all-time:
  • Site-wide: 7,240
  • In genetic and genomic medicine: 20
• Year to date:
  • Site-wide: 23,527
• Since beginning of last month:
  • Site-wide: 18,715

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

• Downloaded 1,704 times
• Download rankings, all-time:
  • Site-wide: 8,893
  • In genetics: 440
• Year to date:
  • Site-wide: 56,881
• Since beginning of last month:
  • Site-wide: 53,954

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

• Downloaded 1,637 times
• Download rankings, all-time:
  • Site-wide: 9,448
  • In genetics: 464
• Year to date:
  • Site-wide: 80,032
• Since beginning of last month:
  • Site-wide: 77,425

metaCCA: Summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis

• Downloaded 1,576 times
• Download rankings, all-time:
  • Site-wide: 9,997
  • In bioinformatics: 1,233
• Year to date:
  • Site-wide: 82,561
• Since beginning of last month:
  • Site-wide: 93,475

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

• Downloaded 1,571 times
• Download rankings, all-time:
  • Site-wide: 10,033
  • In genomics: 1,109
• Year to date:
  • Site-wide: 55,424
• Since beginning of last month:
  • Site-wide: 44,836

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

• Downloaded 1,401 times
• Download rankings, all-time:
  • Site-wide: 11,869
  • In genetics: 596
• Year to date:
  • Site-wide: 84,480
• Since beginning of last month:
  • Site-wide: 87,268

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

• Downloaded 1,187 times
• Download rankings, all-time:
  • Site-wide: 15,229
  • In genetics: 782
• Year to date:
  • Site-wide: 34,616
• Since beginning of last month:
  • Site-wide: 32,129

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

• Downloaded 1,026 times
• Download rankings, all-time:
  • Site-wide: 19,017
  • In genetics: 946
• Year to date:
  • Site-wide: 6,568
• Since beginning of last month:
  • Site-wide: 6,681

An epigenome-wide association study of educational attainment (n = 10,767)

• Downloaded 984 times
• Download rankings, all-time:
  • Site-wide: 20,157
  • In genetics: 1,001
• Year to date:
  • Site-wide: 47,778
• Since beginning of last month:
  • Site-wide: 44,609

Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

• Downloaded 979 times
• Download rankings, all-time:
  • Site-wide: 20,287
  • In epidemiology: 1,170
• Year to date:
  • Site-wide: 72,577
• Since beginning of last month:
  • Site-wide: 77,215

Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

• Downloaded 949 times
• Download rankings, all-time:
  • Site-wide: 21,208
  • In genomics: 2,125
• Year to date:
  • Site-wide: 72,265
• Since beginning of last month:
  • Site-wide: 51,020

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

• Downloaded 813 times
• Download rankings, all-time:
  • Site-wide: 26,434
  • In genetics: 1,315
• Year to date:
  • Site-wide: 47,821
• Since beginning of last month:
  • Site-wide: 65,378

Lower hemoglobin levels associate with lower body mass index and healthier metabolic profile

• Downloaded 809 times
• Download rankings, all-time:
  • Site-wide: 26,622
  • In epidemiology: 1,397
• Year to date:
  • Site-wide: 37,845
• Since beginning of last month:
  • Site-wide: 29,163

Genetic Association Study of Childhood Aggression across raters, instruments and age

• Downloaded 796 times
• Download rankings, all-time:
  • Site-wide: 27,205
  • In genomics: 2,567
• Year to date:
  • Site-wide: 34,133
• Since beginning of last month:
  • Site-wide: 29,624

An interaction map of circulating metabolites, immune gene networks and their genetic regulation

• Downloaded 760 times
• Download rankings, all-time:
  • Site-wide: 29,031
  • In genomics: 2,671
• Year to date:
  • Site-wide: 98,327
• Since beginning of last month:
  • Site-wide: 66,800

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

• Downloaded 746 times
• Download rankings, all-time:
  • Site-wide: 29,807
  • In genomics: 2,731
• Year to date:
  • Site-wide: 72,834
• Since beginning of last month:
  • Site-wide: 66,779

Genetic and environmental perturbations lead to regulatory decoherence

• Downloaded 737 times
• Download rankings, all-time:
  • Site-wide: 30,277
  • In genomics: 2,762
• Year to date:
  • Site-wide: 111,649
• Since beginning of last month:
  • Site-wide: 93,670

Metabolic profiling of alcohol consumption in 9778 young adults

• Downloaded 601 times
• Download rankings, all-time:
  • Site-wide: 39,726
  • In systems biology: 926
• Year to date:
  • Site-wide: 43,347
• Since beginning of last month:
  • Site-wide: 17,733

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

• Downloaded 601 times
• Download rankings, all-time:
  • Site-wide: 39,704
  • In genetics: 1,920
• Year to date:
  • Site-wide: 68,405
• Since beginning of last month:
  • Site-wide: 62,849

Metabolic Effects Of Risk Alleles In PNPLA3, TM6SF2, GCKR, And LYPLAL1 Inform About Heterogeneity Of Non-Alcoholic Fatty Liver Disease

• Downloaded 593 times
• Download rankings, all-time:
  • Site-wide: 40,395
  • In epidemiology: 1,900
• Year to date:
  • Site-wide: 73,675
• Since beginning of last month:
  • Site-wide: 64,018

Discovering patterns of pleiotropy in genome-wide association studies

• Downloaded 573 times
• Download rankings, all-time:
  • Site-wide: 42,104
  • In genetics: 2,027
• Year to date:
  • Site-wide: 103,750
• Since beginning of last month:
  • Site-wide: 88,693

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

• Downloaded 561 times
• Download rankings, all-time:
  • Site-wide: 43,374
  • In genetics: 2,087
• Year to date:
  • Site-wide: 83,134
• Since beginning of last month:
  • Site-wide: 46,343

Metabolic signatures of birth weight in 18288 adolescents and adults

• Downloaded 542 times
• Download rankings, all-time:
  • Site-wide: 45,195
  • In systems biology: 1,053
• Year to date:
  • Site-wide: 104,527
• Since beginning of last month:
  • Site-wide: None

Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

• Downloaded 526 times
• Download rankings, all-time:
  • Site-wide: 46,842
  • In genomics: 3,785
• Year to date:
  • Site-wide: 98,004
• Since beginning of last month:
  • Site-wide: 64,264

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

• Downloaded 501 times
• Download rankings, all-time:
  • Site-wide: 49,640
  • In genomics: 3,928
• Year to date:
  • Site-wide: 109,166
• Since beginning of last month:
  • Site-wide: 98,130

Meta-analysis of exome array data identifies six novel genetic loci for lung function

• Downloaded 475 times
• Download rankings, all-time:
  • Site-wide: 52,664
  • In genetics: 2,505
• Year to date:
  • Site-wide: 85,583
• Since beginning of last month:
  • Site-wide: 66,940

The landscape of incident disease risk for the biomarker GlycA and its mortality stratification in angiography patients

• Downloaded 448 times
• Download rankings, all-time:
  • Site-wide: 56,183
  • In epidemiology: 2,394
• Year to date:
  • Site-wide: 95,947
• Since beginning of last month:
  • Site-wide: None

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns

• Downloaded 404 times
• Download rankings, all-time:
  • Site-wide: 62,486
  • In genetics: 2,945
• Year to date:
  • Site-wide: 117,260
• Since beginning of last month:
  • Site-wide: None

Consortium genome-wide meta-analysis for childhood dental caries traits

• Downloaded 386 times
• Download rankings, all-time:
  • Site-wide: 65,241
  • In genetics: 3,066
• Year to date:
  • Site-wide: 110,257
• Since beginning of last month:
  • Site-wide: 101,527

Secondary Vulvodynia Patients Show Reduced Bacterial Diversity in Vestibular Microbiome

• Downloaded 368 times
• Download rankings, all-time:
  • Site-wide: 68,270
  • In obstetrics and gynecology: 40
• Year to date:
  • Site-wide: 42,237
• Since beginning of last month:
  • Site-wide: 42,536

Genome-wide association meta-analysis of childhood and adolescent internalising symptoms

• Downloaded 365 times
• Download rankings, all-time:
  • Site-wide: 68,730
  • In psychiatry and clinical psychology: 206
• Year to date:
  • Site-wide: 17,704
• Since beginning of last month:
  • Site-wide: 10,653

Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition

• Downloaded 360 times
• Download rankings, all-time:
  • Site-wide: 69,602
  • In genetics: 3,249
• Year to date:
  • Site-wide: 90,625
• Since beginning of last month:
  • Site-wide: 80,262

Genetic variation in apolipoprotein A-I concentrations and risk of coronary artery disease

• Downloaded 321 times
• Download rankings, all-time:
  • Site-wide: 76,529
  • In epidemiology: 3,149
• Year to date:
  • Site-wide: 92,759
• Since beginning of last month:
  • Site-wide: 78,044

A genome-wide association study of total child psychiatric problems scores

• Downloaded 278 times
• Download rankings, all-time:
  • Site-wide: 85,186
  • In psychiatry and clinical psychology: 278
• Year to date:
  • Site-wide: 59,096
• Since beginning of last month:
  • Site-wide: 58,255

Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles

• Downloaded 251 times
• Download rankings, all-time:
  • Site-wide: 90,901
  • In genetic and genomic medicine: 318
• Year to date:
  • Site-wide: 3,381
• Since beginning of last month:
  • Site-wide: 5,916

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

• Downloaded 247 times
• Download rankings, all-time:
  • Site-wide: 91,728
  • In genetics: 4,184
• Year to date:
  • Site-wide: 39,325
• Since beginning of last month:
  • Site-wide: 34,316

Genetic study of circulating cytokines offers insight into the determinants, cascades and effects of systemic inflammation

• Downloaded 206 times
• Download rankings, all-time:
  • Site-wide: 100,543
  • In epidemiology: 4,103
• Year to date:
  • Site-wide: 23,811
• Since beginning of last month:
  • Site-wide: 30,619

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

• Downloaded 199 times
• Download rankings, all-time:
  • Site-wide: 102,161
  • In genomics: 6,025
• Year to date:
  • Site-wide: 101,479
• Since beginning of last month:
  • Site-wide: 103,362

Gene regulation contributes to explain the impact of early life socioeconomic disadvantage on adult inflammatory levels in two European cohort studies

• Downloaded 166 times
• Download rankings, all-time:
  • Site-wide: 108,957
  • In epidemiology: 4,431
• Year to date:
  • Site-wide: 65,970
• Since beginning of last month:
  • Site-wide: 50,595

Elevated glycoprotein acetyl levels in adolescence and early adulthood predict adverse cardiometabolic profiles and risk of metabolic syndrome in up to 10 year follow-up

• Downloaded 134 times
• Download rankings, all-time:
  • Site-wide: 115,039
  • In cardiovascular medicine: 273
• Year to date:
  • Site-wide: 90,066
• Since beginning of last month:
  • Site-wide: 75,674