Author: Philip L De Jager

ORCiD: http://orcid.org/0000-0002-8057-2505
Most recently observed institution: Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center

Rankings

All-time downloads: 37,493 (rank: 962 out of 364,858)
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- bioinformatics: 667 (rank: 14,887 (tie) out of 31,493)
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- genomics: 8,801 (rank: 1,595 out of 39,301)
- immunology: 1,391 (rank: 2,217 out of 18,981)
- neuroscience: 9,299 (rank: 731 out of 61,227)
- systems biology: 1,736 (rank: 1,557 (tie) out of 10,834)

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Preprints

Genetic determinants of co-accessible chromatin regions in T cell activation across humans

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A single cell-based atlas of human microglial states reveals associations with neurological disorders and histopathological features of the aging brain

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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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A Bayesian approach to mediation analysis predicts 206 causal target genes in Alzheimer's disease

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A Consensus Proteomic Analysis of Alzheimer’s Disease Brain and Cerebrospinal Fluid Reveals Early Changes in Energy Metabolism Associated with Microglia and Astrocyte Activation

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Integrative analyses of splicing in the aging brain: role in susceptibility to Alzheimer's Disease

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Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

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Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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Altered Bile Acid Profile Associates with Cognitive Impairment in Alzheimer's Disease: An Emerging Role for Gut Microbiome

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BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 implicated in Tau pathology

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Epigenome-wide study uncovers tau pathology-driven changes of chromatin organization in the aging human brain

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Systems genetics identifies modifiers of Alzheimer's disease risk and resilience

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Shared effect modeling reveals that a fraction of autoimmune disease associations are consistent with eQTLs in three immune cell types

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A cortical immune network map identifies a subset of human microglia involved in Tau pathology

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Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection

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Deconvolving the contributions of cell-type heterogeneity on cortical gene expression

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A Novel Tmem119-tdTomato Reporter Mouse Model for Studying Microglia in the Central Nervous System

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Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

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Genetic control of the human brain proteome

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Tau-mediated Disruption of the Spliceosome Triggers Cryptic RNA-splicing and Neurodegeneration in Alzheimer's Disease

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Partial derivatives meta-analysis: pooled analyses when individual participant data cannot be shared

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TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits

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The landscape of myeloid and astrocyte phenotypes in acute multiple sclerosis lesions

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Genetic data and cognitively-defined late-onset Alzheimer's disease subgroups

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Neuropathological correlates and genetic architecture of microglial activation in elderly human brain

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Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer's disease.

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Integrated analysis of the aging brain transcriptome and proteome in tauopathy

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Meta-analysis of epigenome-wide association studies in Alzheime's disease highlights 220 differentially methylated loci across cortex

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Novel Bayesian transcriptome-wide association study method leveraging both cis- and trans- eQTL information through summary statistics

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Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia

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Brain DNA Methylation Patterns in CLDN5 Associated With Cognitive Decline

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Peripheral Serum Metabolomic Profiles Inform Antecedent Central Cognitive Impairment in Older Adults

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