Author: Phillip De Jager
- ORCiD: http://orcid.org/0000-0002-8057-2505
- Most recently observed institution: Columbia University Irving Medical Center
Rankings
- All-time downloads: 49,722 (rank: 2,664 )
- Categories:
- bioinformatics: 709 (rank: 18,509 (tie) )
- cell biology: 1,430 (rank: 4,513 (tie) )
- genetic and genomic medicine: 626 (rank: 2,730 (tie) )
- genetics: 17,011 (rank: 796 )
- genomics: 10,219 (rank: 1,739 )
- immunology: 1,718 (rank: 4,635 )
- neuroscience: 11,186 (rank: 972 )
- pathology: 4,222 (rank: 269 (tie) )
- systems biology: 2,601 (rank: 1,422 )
Downloads per author, site-wide
Preprints
Genetic determinants of co-accessible chromatin regions in T cell activation across humans
genomics more details view paper- Downloaded 5,019 times
- Download rankings, all-time:
- Site-wide: 1,846
- In genomics: 191
- Year to date:
- Site-wide: 35,206
- Since beginning of last month:
- Site-wide: 23,522
A single cell-based atlas of human microglial states reveals associations with neurological disorders and histopathological features of the aging brain
neuroscience more details view paper- Downloaded 4,313 times
- Download rankings, all-time:
- Site-wide: 2,293
- In neuroscience: 151
- Year to date:
- Site-wide: 22,325
- Since beginning of last month:
- Site-wide: 13,625
EXCEPTIONALLY LOW LIKELIHOOD OF ALZHEIMER'S DEMENTIA IN APOE2 HOMOZYGOTES
pathology more details view paper- Downloaded 4,072 times
- Download rankings, all-time:
- Site-wide: 2,474
- In pathology: 18
- Year to date:
- Site-wide: 23,858
- Since beginning of last month:
- Site-wide: 27,839
A Bayesian approach to mediation analysis predicts 206 causal target genes in Alzheimer's disease
genetics more details view paper- Downloaded 3,309 times
- Download rankings, all-time:
- Site-wide: 3,360
- In genetics: 136
- Year to date:
- Site-wide: 15,724
- Since beginning of last month:
- Site-wide: 16,671
Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)
genetics more details view paper- Downloaded 3,247 times
- Download rankings, all-time:
- Site-wide: 3,473
- In genetics: 149
- Year to date:
- Site-wide: 25,922
- Since beginning of last month:
- Site-wide: 26,882
A Consensus Proteomic Analysis of Alzheimer’s Disease Brain and Cerebrospinal Fluid Reveals Early Changes in Energy Metabolism Associated with Microglia and Astrocyte Activation
systems biology more details view paper- Downloaded 2,102 times
- Download rankings, all-time:
- Site-wide: 6,474
- In systems biology: 113
- Year to date:
- Site-wide: 19,254
- Since beginning of last month:
- Site-wide: 14,547
Integrative analyses of splicing in the aging brain: role in susceptibility to Alzheimer's Disease
genomics more details view paper- Downloaded 1,784 times
- Download rankings, all-time:
- Site-wide: 8,270
- In genomics: 930
- Year to date:
- Site-wide: 94,954
- Since beginning of last month:
- Site-wide: None
Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism
genetics more details view paper- Downloaded 1,704 times
- Download rankings, all-time:
- Site-wide: 8,899
- In genetics: 440
- Year to date:
- Site-wide: 57,604
- Since beginning of last month:
- Site-wide: 55,079
Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide
genetics more details view paper- Downloaded 1,700 times
- Download rankings, all-time:
- Site-wide: 8,934
- In genetics: 442
- Year to date:
- Site-wide: 98,198
- Since beginning of last month:
- Site-wide: None
Altered Bile Acid Profile Associates with Cognitive Impairment in Alzheimer's Disease: An Emerging Role for Gut Microbiome
neuroscience more details view paper- Downloaded 1,446 times
- Download rankings, all-time:
- Site-wide: 11,318
- In neuroscience: 1,284
- Year to date:
- Site-wide: 39,741
- Since beginning of last month:
- Site-wide: 45,738
BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 implicated in Tau pathology
cell biology more details view paper- Downloaded 1,430 times
- Download rankings, all-time:
- Site-wide: 11,511
- In cell biology: 315
- Year to date:
- Site-wide: 51,222
- Since beginning of last month:
- Site-wide: None
Epigenome-wide study uncovers tau pathology-driven changes of chromatin organization in the aging human brain
neuroscience more details view paper- Downloaded 1,167 times
- Download rankings, all-time:
- Site-wide: 15,640
- In neuroscience: 1,934
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: None
Systems genetics identifies modifiers of Alzheimer's disease risk and resilience
genetics more details view paper- Downloaded 1,163 times
- Download rankings, all-time:
- Site-wide: 15,717
- In genetics: 797
- Year to date:
- Site-wide: 71,660
- Since beginning of last month:
- Site-wide: 67,147
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions
genetics more details view paper- Downloaded 1,117 times
- Download rankings, all-time:
- Site-wide: 16,739
- In genetics: 846
- Year to date:
- Site-wide: 48,768
- Since beginning of last month:
- Site-wide: None
Shared effect modeling reveals that a fraction of autoimmune disease associations are consistent with eQTLs in three immune cell types
genetics more details view paper- Downloaded 1,105 times
- Download rankings, all-time:
- Site-wide: 17,008
- In genetics: 864
- Year to date:
- Site-wide: 117,417
- Since beginning of last month:
- Site-wide: 87,579
Genetic control of the human brain proteome
genetics more details view paper- Downloaded 1,097 times
- Download rankings, all-time:
- Site-wide: 17,185
- In genetics: 873
- Year to date:
- Site-wide: 14,885
- Since beginning of last month:
- Site-wide: 11,330
A cortical immune network map identifies a subset of human microglia involved in Tau pathology
neuroscience more details view paper- Downloaded 1,066 times
- Download rankings, all-time:
- Site-wide: 17,907
- In neuroscience: 2,260
- Year to date:
- Site-wide: 37,920
- Since beginning of last month:
- Site-wide: 52,509
A Novel Tmem119-tdTomato Reporter Mouse Model for Studying Microglia in the Central Nervous System
immunology more details view paper- Downloaded 1,054 times
- Download rankings, all-time:
- Site-wide: 18,225
- In immunology: 510
- Year to date:
- Site-wide: 21,703
- Since beginning of last month:
- Site-wide: 29,458
Deconvolving the contributions of cell-type heterogeneity on cortical gene expression
neuroscience more details view paper- Downloaded 1,050 times
- Download rankings, all-time:
- Site-wide: 18,325
- In neuroscience: 2,333
- Year to date:
- Site-wide: 51,109
- Since beginning of last month:
- Site-wide: 30,322
Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection
genomics more details view paper- Downloaded 955 times
- Download rankings, all-time:
- Site-wide: 21,023
- In genomics: 2,114
- Year to date:
- Site-wide: 92,514
- Since beginning of last month:
- Site-wide: None
Meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex
genomics more details view paper- Downloaded 763 times
- Download rankings, all-time:
- Site-wide: 28,851
- In genomics: 2,664
- Year to date:
- Site-wide: 15,487
- Since beginning of last month:
- Site-wide: 11,191
Tau-mediated Disruption of the Spliceosome Triggers Cryptic RNA-splicing and Neurodegeneration in Alzheimer's Disease
neuroscience more details view paper- Downloaded 745 times
- Download rankings, all-time:
- Site-wide: 29,884
- In neuroscience: 4,109
- Year to date:
- Site-wide: 70,754
- Since beginning of last month:
- Site-wide: 53,939
Partial derivatives meta-analysis: pooled analyses when individual participant data cannot be shared
bioinformatics more details view paper- Downloaded 709 times
- Download rankings, all-time:
- Site-wide: 31,994
- In bioinformatics: 3,633
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: None
TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits
genetics more details view paper- Downloaded 672 times
- Download rankings, all-time:
- Site-wide: 34,400
- In genetics: 1,681
- Year to date:
- Site-wide: 74,341
- Since beginning of last month:
- Site-wide: None
Bayesian Genome-wide TWAS method to leverage both cis- and trans- eQTL information through summary statistics
genetics more details view paper- Downloaded 667 times
- Download rankings, all-time:
- Site-wide: 34,730
- In genetics: 1,698
- Year to date:
- Site-wide: 23,300
- Since beginning of last month:
- Site-wide: 25,709
The landscape of myeloid and astrocyte phenotypes in acute multiple sclerosis lesions
immunology more details view paper- Downloaded 664 times
- Download rankings, all-time:
- Site-wide: 34,958
- In immunology: 951
- Year to date:
- Site-wide: 71,824
- Since beginning of last month:
- Site-wide: 86,217
Genetic data and cognitively-defined late-onset Alzheimer's disease subgroups
genetics more details view paper- Downloaded 587 times
- Download rankings, all-time:
- Site-wide: 40,936
- In genetics: 1,971
- Year to date:
- Site-wide: 107,909
- Since beginning of last month:
- Site-wide: 82,229
Neuropathological correlates and genetic architecture of microglial activation in elderly human brain
genomics more details view paper- Downloaded 555 times
- Download rankings, all-time:
- Site-wide: 43,924
- In genomics: 3,594
- Year to date:
- Site-wide: 81,219
- Since beginning of last month:
- Site-wide: 69,361
Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer's disease.
neuroscience more details view paper- Downloaded 551 times
- Download rankings, all-time:
- Site-wide: 44,305
- In neuroscience: 6,466
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: None
Multi-cellular communities are perturbed in the aging human brain and with Alzheimer's disease
neuroscience more details view paper- Downloaded 513 times
- Download rankings, all-time:
- Site-wide: 48,236
- In neuroscience: 7,121
- Year to date:
- Site-wide: 1,914
- Since beginning of last month:
- Site-wide: 5,641
Integrated analysis of the aging brain transcriptome and proteome in tauopathy
genomics more details view paper- Downloaded 509 times
- Download rankings, all-time:
- Site-wide: 48,643
- In genomics: 3,880
- Year to date:
- Site-wide: 58,549
- Since beginning of last month:
- Site-wide: 77,213
Single Cell-type Integrative Network Modeling Identified Novel Microglial-specific Targets for the Phagosome in Alzheimer's disease
systems biology more details view paper- Downloaded 499 times
- Download rankings, all-time:
- Site-wide: 49,829
- In systems biology: 1,180
- Year to date:
- Site-wide: 27,115
- Since beginning of last month:
- Site-wide: 21,228
Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia
genetics more details view paper- Downloaded 434 times
- Download rankings, all-time:
- Site-wide: 58,029
- In genetics: 2,747
- Year to date:
- Site-wide: 13,136
- Since beginning of last month:
- Site-wide: 18,682
Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women
genetic and genomic medicine more details view paper- Downloaded 368 times
- Download rankings, all-time:
- Site-wide: 68,169
- In genetic and genomic medicine: 201
- Year to date:
- Site-wide: 20,959
- Since beginning of last month:
- Site-wide: 19,306
Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia
genomics more details view paper- Downloaded 259 times
- Download rankings, all-time:
- Site-wide: 89,133
- In genomics: 5,602
- Year to date:
- Site-wide: 87,233
- Since beginning of last month:
- Site-wide: None
Association between DNA Methylation Levels in Brain Tissue and Late-Life Depression in Community-Based Participants
genetic and genomic medicine more details view paper- Downloaded 258 times
- Download rankings, all-time:
- Site-wide: 89,532
- In genetic and genomic medicine: 305
- Year to date:
- Site-wide: 42,669
- Since beginning of last month:
- Site-wide: 35,680
The Caribbean-Hispanic Alzheimer’s Brain Transcriptome Reveals Ancestry-Specific Disease Mechanisms
genomics more details view paper- Downloaded 227 times
- Download rankings, all-time:
- Site-wide: 96,001
- In genomics: 5,844
- Year to date:
- Site-wide: 56,268
- Since beginning of last month:
- Site-wide: 41,269
Brain DNA Methylation Patterns in CLDN5 Associated With Cognitive Decline
genetics more details view paper- Downloaded 209 times
- Download rankings, all-time:
- Site-wide: 99,887
- In genetics: 4,517
- Year to date:
- Site-wide: 67,959
- Since beginning of last month:
- Site-wide: 39,041
Peripheral Serum Metabolomic Profiles Inform Antecedent Central Cognitive Impairment in Older Adults
neuroscience more details view paper- Downloaded 179 times
- Download rankings, all-time:
- Site-wide: 106,279
- In neuroscience: 16,602
- Year to date:
- Site-wide: 103,484
- Since beginning of last month:
- Site-wide: 88,587
Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on alzheimer’s disease risk in humans
neuroscience more details view paper- Downloaded 156 times
- Download rankings, all-time:
- Site-wide: 111,083
- In neuroscience: 17,265
- Year to date:
- Site-wide: 72,645
- Since beginning of last month:
- Site-wide: 91,980
Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification
pathology more details view paper- Downloaded 150 times
- Download rankings, all-time:
- Site-wide: 112,139
- In pathology: 648
- Year to date:
- Site-wide: 76,562
- Since beginning of last month:
- Site-wide: None
Impact of genetic susceptibility to multiple sclerosis on the T cell epigenome: proximal and distal effects
genomics more details view paper- Downloaded 148 times
- Download rankings, all-time:
- Site-wide: 112,530
- In genomics: 6,349
- Year to date:
- Site-wide: 87,945
- Since beginning of last month:
- Site-wide: None
PanLingua
News
- 27 Nov 2020: The website and API now include results pulled from medRxiv as well as bioRxiv.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!