Author: David A. Bennett

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Preprints

The Caribbean-Hispanic Alzheimer's Brain Transcriptome Reveals Ancestry-Specific Disease Mechanisms

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A single cell-based atlas of human microglial states reveals associations with neurological disorders and histopathological features of the aging brain

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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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Meta-analysis of the human brain transcriptome identifies heterogeneity across human AD coexpression modules robust to sample collection and methodological approach

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Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia

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A Consensus Proteomic Analysis of Alzheimer’s Disease Brain and Cerebrospinal Fluid Reveals Early Changes in Energy Metabolism Associated with Microglia and Astrocyte Activation

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Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

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Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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Altered Bile Acid Profile Associates with Cognitive Impairment in Alzheimer's Disease: An Emerging Role for Gut Microbiome

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BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 implicated in Tau pathology

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Epigenome-wide study uncovers tau pathology-driven changes of chromatin organization in the aging human brain

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A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research

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Systems genetics identifies modifiers of Alzheimer's disease risk and resilience

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A cortical immune network map identifies a subset of human microglia involved in Tau pathology

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Deconvolving the contributions of cell-type heterogeneity on cortical gene expression

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Genetic control of the human brain proteome

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Tau-mediated Disruption of the Spliceosome Triggers Cryptic RNA-splicing and Neurodegeneration in Alzheimer's Disease

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Partial derivatives meta-analysis: pooled analyses when individual participant data cannot be shared

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Lipid associated polygenic enrichment in Alzheimer's disease

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TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits

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Genetic data and cognitively-defined late-onset Alzheimer's disease subgroups

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Neuropathological correlates and genetic architecture of microglial activation in elderly human brain

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Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer's disease.

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Sex-dependent polygenic effects on the clinical progressions of Alzheimer's disease

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Genetic Variants and Functional Pathways Associated with Resilience to Alzheimer's Disease

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Cell type-specific histone acetylation profiling of Alzheimer's Disease subjects and integration with genetics

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Perturbed functional networks in Alzheimers Disease reveal opposing roles for TGIF and EGR3

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Meta-analysis of epigenome-wide association studies in Alzheime's disease highlights 220 differentially methylated loci across cortex

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Exome-wide age-of-onset analysis reveals exonic variants in ERN1, TACR3 and SPPL2C associated with Alzheimer's disease

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PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer's disease

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Cerebral atherosclerosis contributes to Alzheimer's dementia independently of its hallmark amyloid and tau pathologies

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Novel Bayesian transcriptome-wide association study method leveraging both cis- and trans- eQTL information through summary statistics

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Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia

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Brain DNA Methylation Patterns in CLDN5 Associated With Cognitive Decline

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Peripheral Serum Metabolomic Profiles Inform Antecedent Central Cognitive Impairment in Older Adults

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