Author: Ben Lehner

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Preprints

Determining protein structures using genetics

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  • Site-wide: 2,941
  • In systems biology: 40
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  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 84,253

The mutational landscape of a prion-like domain

• Downloaded 1,717 times
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  • Site-wide: 8,166
  • In genetics: 411
• Year to date:
  • Site-wide: 100,831
• Since beginning of last month:
  • Site-wide: 93,638

Noise control is a primary function of microRNAs and post-transcriptional regulation

• Downloaded 1,201 times
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  • Site-wide: 14,020
  • In genetics: 729
• Year to date:
  • Site-wide: 76,261
• Since beginning of last month:
  • Site-wide: 47,964

Single cell expression analysis uncouples transdifferentiation and reprogramming

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  • Site-wide: 18,300
  • In developmental biology: 324
• Year to date:
  • Site-wide: 87,025
• Since beginning of last month:
  • Site-wide: 64,250

Changes in gene expression shift and switch genetic interactions

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  • Site-wide: 19,062
  • In genetics: 968
• Year to date:
  • Site-wide: 47,660
• Since beginning of last month:
  • Site-wide: 49,555

Single cell functional genomics reveals the importance of mitochondria in cell-to-cell variation in proliferation, drug resistance and mutation outcome

• Downloaded 847 times
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  • Site-wide: 23,500
  • In genomics: 2,312
• Year to date:
  • Site-wide: 109,581
• Since beginning of last month:
  • Site-wide: 76,007

Harmonious genetic combinations rewire regulatory networks and flip gene essentiality

• Downloaded 668 times
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  • Site-wide: 32,567
  • In genetics: 1,636
• Year to date:
  • Site-wide: 102,846
• Since beginning of last month:
  • Site-wide: 100,050

Empirical noise-mean fitness landscapes and the evolution of gene expression

• Downloaded 648 times
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  • Site-wide: 33,896
  • In systems biology: 787
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 121,602

DiMSum: an error model and pipeline for analyzing deep mutational scanning data and diagnosing common experimental pathologies

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  • Site-wide: 70,228
  • In bioinformatics: 6,736
• Year to date:
  • Site-wide: 75,354
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  • Site-wide: 107,622

The genetic landscape for amyloid beta fibril nucleation accurately discriminates familial Alzheimer’s disease mutations

• Downloaded 327 times
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  • Site-wide: 71,324
  • In genomics: 4,944
• Year to date:
  • Site-wide: 52,740
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  • Site-wide: 66,403

Neuronal perception of the social environment intergenerationally controls germline development and generation time in C. elegans

• Downloaded 286 times
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  • Site-wide: 79,171
  • In genetics: 3,726
• Year to date:
  • Site-wide: 32,234
• Since beginning of last month:
  • Site-wide: 35,942

Mutations primarily alter the inclusion of alternatively spliced exons

• Downloaded 273 times
• Download rankings, all-time:
  • Site-wide: 81,608
  • In genomics: 5,312
• Year to date:
  • Site-wide: 50,150
• Since beginning of last month:
  • Site-wide: 49,589