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Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 73,446 bioRxiv papers from 319,713 authors.

Author: Detlef Weigel

Rankings

  • All-time downloads: 100,612 (rank: 107 out of 319,669)
  • Categories:
    • bioinformatics: 25,824 (rank: 70 out of 27,710)
    • cancer biology: 1,898 (rank: 1,281 (tie) out of 21,049)
    • cell biology: 916 (rank: 3,897 (tie) out of 22,440)
    • developmental biology: 7,167 (rank: 35 out of 12,294)
    • genetics: 10,562 (rank: 954 out of 31,309)
    • genomics: 53,437 (rank: 108 out of 35,644)
    • neuroscience: 227 (rank: 40,747 (tie) out of 53,999)
    • plant biology: 581 (rank: 3,739 (tie) out of 11,793)

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Preprints

Benchmarking Single-Cell RNA Sequencing Protocols for Cell Atlas Projects

genomics more details view paper
  • Downloaded 9,600 times
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    • Site-wide: 153 out of 73,447
    • In genomics: 41 out of 4,872
  • Year to date:
    • Site-wide: 273 out of 73,447
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    • Site-wide: 273 out of 73,447

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

genomics more details view paper
  • Downloaded 6,528 times
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    • Site-wide: 311 out of 73,447
    • In genomics: 78 out of 4,872
  • Year to date:
    • Site-wide: 753 out of 73,447
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    • Site-wide: 753 out of 73,447

Accurate prediction of single-cell DNA methylation states using deep learning

bioinformatics more details view paper
  • Downloaded 6,006 times
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    • Site-wide: 362 out of 73,447
    • In bioinformatics: 68 out of 7,156
  • Year to date:
    • Site-wide: 24,826 out of 73,447
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    • Site-wide: 24,826 out of 73,447

LIMIX: genetic analysis of multiple traits

genetics more details view paper
  • Downloaded 5,804 times
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    • Site-wide: 382 out of 73,447
    • In genetics: 41 out of 4,031
  • Year to date:
    • Site-wide: 18,696 out of 73,447
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    • Site-wide: 18,696 out of 73,447

Single cell multi-omics profiling reveals a hierarchical epigenetic landscape during mammalian germ layer specification

developmental biology more details view paper
  • Downloaded 5,525 times
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    • Site-wide: 414 out of 73,447
    • In developmental biology: 6 out of 2,204
  • Year to date:
    • Site-wide: 2,147 out of 73,447
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    • Site-wide: 2,147 out of 73,447

Multi-Omics factor analysis - a framework for unsupervised integration of multi-omic data sets

bioinformatics more details view paper
  • Downloaded 4,610 times
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    • Site-wide: 584 out of 73,447
    • In bioinformatics: 115 out of 7,156
  • Year to date:
    • Site-wide: 23,811 out of 73,447
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    • Site-wide: 23,811 out of 73,447

scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells

genomics more details view paper
  • Downloaded 4,594 times
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    • In genomics: 144 out of 4,872
  • Year to date:
    • Site-wide: 20,346 out of 73,447
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    • Site-wide: 20,346 out of 73,447

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

genomics more details view paper
  • Downloaded 4,453 times
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    • Site-wide: 628 out of 73,447
    • In genomics: 156 out of 4,872
  • Year to date:
    • Site-wide: 3,790 out of 73,447
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    • Site-wide: 3,790 out of 73,447

Cardelino: Integrating whole exomes and single-cell transcriptomes to reveal phenotypic impact of somatic variants

genomics more details view paper
  • Downloaded 4,135 times
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    • In genomics: 176 out of 4,872
  • Year to date:
    • Site-wide: 2,838 out of 73,447
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    • Site-wide: 2,838 out of 73,447

Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types

genomics more details view paper
  • Downloaded 3,752 times
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    • Site-wide: 873 out of 73,447
    • In genomics: 215 out of 4,872
  • Year to date:
    • Site-wide: 2,714 out of 73,447
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    • Site-wide: 2,714 out of 73,447

Modelling cell-cell interactions from spatial molecular data with spatial variance component analysis

bioinformatics more details view paper
  • Downloaded 3,244 times
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    • Site-wide: 1,156 out of 73,447
    • In bioinformatics: 229 out of 7,156
  • Year to date:
    • Site-wide: 8,857 out of 73,447
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    • Site-wide: 8,857 out of 73,447

Kipoi: accelerating the community exchange and reuse of predictive models for genomics

bioinformatics more details view paper
  • Downloaded 3,080 times
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    • Site-wide: 1,265 out of 73,447
    • In bioinformatics: 251 out of 7,156
  • Year to date:
    • Site-wide: 2,560 out of 73,447
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    • Site-wide: 2,560 out of 73,447

Scalable latent-factor models applied to single-cell RNA-seq data separate biological drivers from confounding effects

bioinformatics more details view paper
  • Downloaded 2,800 times
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    • Site-wide: 1,487 out of 73,447
    • In bioinformatics: 296 out of 7,156
  • Year to date:
    • Site-wide: 52,981 out of 73,447
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    • Site-wide: 52,981 out of 73,447

SpatialDE - Identification of spatially variable genes

genomics more details view paper
  • Downloaded 2,792 times
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    • Site-wide: 1,493 out of 73,447
    • In genomics: 335 out of 4,872
  • Year to date:
    • Site-wide: 24,797 out of 73,447
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    • Site-wide: 24,797 out of 73,447

Common genetic variation drives molecular heterogeneity in human iPSCs

genomics more details view paper
  • Downloaded 2,628 times
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    • Site-wide: 1,664 out of 73,447
    • In genomics: 365 out of 4,872
  • Year to date:
    • Site-wide: 37,414 out of 73,447
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    • Site-wide: 37,414 out of 73,447

Single-cell RNA-seq of differentiating iPS cells reveals dynamic genetic effects on gene expression

genomics more details view paper
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    • Site-wide: 2,273 out of 73,447
    • In genomics: 475 out of 4,872
  • Year to date:
    • Site-wide: 2,031 out of 73,447
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    • Site-wide: 2,031 out of 73,447

A linear mixed model approach to study multivariate gene-environment interactions

genetics more details view paper
  • Downloaded 2,138 times
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    • Site-wide: 2,416 out of 73,447
    • In genetics: 219 out of 4,031
  • Year to date:
    • Site-wide: 23,700 out of 73,447
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    • Site-wide: 23,700 out of 73,447

A Pan-Cancer Transcriptome Analysis Reveals Pervasive Regulation through Tumor-Associated Alternative Promoters

genomics more details view paper
  • Downloaded 2,051 times
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    • Site-wide: 2,595 out of 73,447
    • In genomics: 528 out of 4,872
  • Year to date:
    • Site-wide: 21,215 out of 73,447
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    • Site-wide: 21,215 out of 73,447

A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of zygotic genome activation

developmental biology more details view paper
  • Downloaded 1,642 times
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    • Site-wide: 3,794 out of 73,447
    • In developmental biology: 64 out of 2,204
  • Year to date:
    • Site-wide: 1,704 out of 73,447
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    • Site-wide: 1,704 out of 73,447

Image-based methods for phenotyping growth dynamics and fitness in Arabidopsis thaliana

bioinformatics more details view paper
  • Downloaded 1,453 times
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    • Site-wide: 4,674 out of 73,447
    • In bioinformatics: 896 out of 7,156
  • Year to date:
    • Site-wide: 12,022 out of 73,447
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    • Site-wide: 12,022 out of 73,447

Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference

bioinformatics more details view paper
  • Downloaded 1,321 times
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    • Site-wide: 5,471 out of 73,447
    • In bioinformatics: 1,037 out of 7,156
  • Year to date:
    • Site-wide: 11,386 out of 73,447
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    • Site-wide: 11,386 out of 73,447

Assessing the Gene Regulatory Landscape in 1,188 Human Tumors

cancer biology more details view paper
  • Downloaded 1,286 times
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    • Site-wide: 5,706 out of 73,447
    • In cancer biology: 152 out of 2,515
  • Year to date:
    • Site-wide: 34,953 out of 73,447
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    • Site-wide: 34,953 out of 73,447

MOFA+: a probabilistic framework for comprehensive integration of structured single-cell data

bioinformatics more details view paper
  • Downloaded 1,243 times
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    • Site-wide: 6,046 out of 73,447
    • In bioinformatics: 1,141 out of 7,156
  • Year to date:
    • Site-wide: 644 out of 73,447
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    • Site-wide: 644 out of 73,447

Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity

bioinformatics more details view paper
  • Downloaded 1,207 times
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    • Site-wide: 6,388 out of 73,447
    • In bioinformatics: 1,190 out of 7,156
  • Year to date:
    • Site-wide: 29,722 out of 73,447
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    • Site-wide: 29,722 out of 73,447

Screening for genes that accelerate the epigenetic ageing clock in humans reveals a role for the H3K36 methyltransferase NSD1

genomics more details view paper
  • Downloaded 1,193 times
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    • Site-wide: 6,510 out of 73,447
    • In genomics: 1,063 out of 4,872
  • Year to date:
    • Site-wide: 13,803 out of 73,447
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    • Site-wide: 13,803 out of 73,447

LiMMBo: a simple, scalable approach for linear mixed models in high-dimensional genetic association studies

genomics more details view paper
  • Downloaded 1,076 times
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    • Site-wide: 7,699 out of 73,447
    • In genomics: 1,215 out of 4,872
  • Year to date:
    • Site-wide: 22,299 out of 73,447
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    • Site-wide: 22,299 out of 73,447

Population-scale proteome variation in human induced pluripotent stem cells

genomics more details view paper
  • Downloaded 1,052 times
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    • Site-wide: 7,997 out of 73,447
    • In genomics: 1,253 out of 4,872
  • Year to date:
    • Site-wide: 21,983 out of 73,447
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    • Site-wide: 21,983 out of 73,447

Comparative architectures of direct and social genetic effects from the genome-wide association study of 170 phenotypes in laboratory mice

genetics more details view paper
  • Downloaded 991 times
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    • Site-wide: 8,820 out of 73,447
    • In genetics: 654 out of 4,031
  • Year to date:
    • Site-wide: 10,273 out of 73,447
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    • Site-wide: 10,273 out of 73,447

Genome-scale oscillations in DNA methylation during exit from pluripotency

genomics more details view paper
  • Downloaded 957 times
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    • Site-wide: 9,365 out of 73,447
    • In genomics: 1,414 out of 4,872
  • Year to date:
    • Site-wide: 63,202 out of 73,447
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    • Site-wide: 63,202 out of 73,447

Genome-wide Analysis of Differential Transcriptional and Epigenetic Variability Across Human Immune Cell Types

genomics more details view paper
  • Downloaded 956 times
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    • Site-wide: 9,394 out of 73,447
    • In genomics: 1,417 out of 4,872
  • Year to date:
    • Site-wide: 51,507 out of 73,447
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    • Site-wide: 51,507 out of 73,447

Identifying extrinsic versus intrinsic drivers of variation in cell behaviour in human iPS cell lines from healthy donors

cell biology more details view paper
  • Downloaded 916 times
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    • Site-wide: 10,016 out of 73,447
    • In cell biology: 370 out of 3,624
  • Year to date:
    • Site-wide: 48,437 out of 73,447
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    • Site-wide: 48,437 out of 73,447

Systematic assessment of regulatory effects of human disease variants in pluripotent cells

genomics more details view paper
  • Downloaded 862 times
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    • Site-wide: 11,067 out of 73,447
    • In genomics: 1,602 out of 4,872
  • Year to date:
    • Site-wide: 5,982 out of 73,447
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    • Site-wide: 5,982 out of 73,447

Robustness and applicability of functional genomics tools on scRNA-seq data

bioinformatics more details view paper
  • Downloaded 860 times
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    • Site-wide: 11,105 out of 73,447
    • In bioinformatics: 1,857 out of 7,156
  • Year to date:
    • Site-wide: 4,555 out of 73,447
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    • Site-wide: 4,555 out of 73,447

Genomic Rearrangements Considered as Quantitative Traits

genetics more details view paper
  • Downloaded 736 times
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    • In genetics: 950 out of 4,031
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    • Site-wide: 55,829 out of 73,447
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    • Site-wide: 55,829 out of 73,447

Century-scale methylome stability in a recently diverged Arabidopsis thaliana lineage

genomics more details view paper
  • Downloaded 725 times
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    • Site-wide: 14,315 out of 73,447
    • In genomics: 1,899 out of 4,872
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    • Site-wide: 57,564 out of 73,447
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    • Site-wide: 57,564 out of 73,447

Tandem duplications lead to loss of fitness effects in CRISPR-Cas9 data

genomics more details view paper
  • Downloaded 681 times
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    • Site-wide: 15,657 out of 73,447
    • In genomics: 1,997 out of 4,872
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Integrative Genome-wide Analysis of the Determinants of RNA Splicing in Kidney Renal Clear Cell Carcinoma

cancer biology more details view paper
  • Downloaded 612 times
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    • In cancer biology: 557 out of 2,515
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    • Site-wide: 52,608 out of 73,447
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    • Site-wide: 52,608 out of 73,447

A Role For The F-Box Protein HAWAIIAN SKIRT In Plant miRNA Function

plant biology more details view paper
  • Downloaded 581 times
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    • Site-wide: 19,708 out of 73,447
    • In plant biology: 483 out of 2,189
  • Year to date:
    • Site-wide: 53,284 out of 73,447
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    • Site-wide: 53,284 out of 73,447

Multi-Tissue DNA Methylation Age Predictor In Mouse

genomics more details view paper
  • Downloaded 545 times
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    • Site-wide: 21,414 out of 73,447
    • In genomics: 2,437 out of 4,872
  • Year to date:
    • Site-wide: 60,931 out of 73,447
  • Since beginning of last month:
    • Site-wide: 60,931 out of 73,447

Genetic associations at regulatory phenotypes improve fine-mapping of causal variants for twelve immune-mediated diseases

genomics more details view paper
  • Downloaded 539 times
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    • Site-wide: 21,758 out of 73,447
    • In genomics: 2,466 out of 4,872
  • Year to date:
    • Site-wide: 300 out of 73,447
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    • Site-wide: 300 out of 73,447

Interactions between genetic variation and cellular environment in skeletal muscle gene expression

genetics more details view paper
  • Downloaded 503 times
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    • Site-wide: 23,792 out of 73,447
    • In genetics: 1,555 out of 4,031
  • Year to date:
    • Site-wide: 54,970 out of 73,447
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    • Site-wide: 54,970 out of 73,447

Genomic properties of structural variants and short tandem repeats that impact gene expression and complex traits in humans

genomics more details view paper
  • Downloaded 476 times
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    • Site-wide: 25,421 out of 73,447
    • In genomics: 2,712 out of 4,872
  • Year to date:
    • Site-wide: 13,509 out of 73,447
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    • Site-wide: 13,509 out of 73,447

DNA sequence properties that predict susceptibility to epiallelic switching

genomics more details view paper
  • Downloaded 467 times
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    • In genomics: 2,753 out of 4,872
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    • Site-wide: 65,794 out of 73,447

Discovery and Quality Analysis of a Comprehensive Set of Structural Variants and Short Tandem Repeats

genomics more details view paper
  • Downloaded 446 times
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    • Site-wide: 27,489 out of 73,447
    • In genomics: 2,850 out of 4,872
  • Year to date:
    • Site-wide: 23,213 out of 73,447
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    • Site-wide: 23,213 out of 73,447

Multi-omics characterization of interaction-mediated control of human protein abundance levels

genomics more details view paper
  • Downloaded 402 times
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    • Site-wide: 30,811 out of 73,447
    • In genomics: 3,076 out of 4,872
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    • Site-wide: 58,909 out of 73,447
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    • Site-wide: 58,909 out of 73,447

Systematic genetic analysis of the MHC region reveals mechanistic underpinnings of HLA type associations with disease

genomics more details view paper
  • Downloaded 310 times
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    • Site-wide: 39,876 out of 73,447
    • In genomics: 3,573 out of 4,872
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    • Site-wide: 52,709 out of 73,447
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    • Site-wide: 52,709 out of 73,447

Using the past to estimate sensory uncertainty

neuroscience more details view paper
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    • Site-wide: 50,618 out of 73,447
    • In neuroscience: 8,959 out of 13,203
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    • Site-wide: 40,656 out of 73,447
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    • Site-wide: 40,656 out of 73,447

Genome-wide scale analyses identify novel BMI genotype-environment interactions using a conditional false discovery rate

genetics more details view paper
  • Downloaded 222 times
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    • Site-wide: 51,257 out of 73,447
    • In genetics: 3,037 out of 4,031
  • Year to date:
    • Site-wide: 1,383 out of 73,447
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    • Site-wide: 1,383 out of 73,447

Genetic Analyses of Blood Cell Structure for Biological and Pharmacological Inference

genetics more details view paper
  • Downloaded 168 times
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    • Site-wide: 59,519 out of 73,447
    • In genetics: 3,427 out of 4,031
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