Author: Leonid Kruglyak

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Preprints

Swab-Seq: A high-throughput platform for massively scaled up SARS-CoV-2 testing

• Downloaded 4,538 times
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  • Site-wide: 1,983
  • In infectious diseases: 424
• Year to date:
  • Site-wide: 1,103
• Since beginning of last month:
  • Site-wide: 2,063

Screening human embryos for polygenic traits has limited utility

• Downloaded 3,392 times
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  • Site-wide: 3,042
  • In genetics: 132
• Year to date:
  • Site-wide: 23,048
• Since beginning of last month:
  • Site-wide: 28,911

CRISPR-directed mitotic recombination enables genetic mapping without crosses

• Downloaded 3,118 times
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  • Site-wide: 3,450
  • In genetics: 157
• Year to date:
  • Site-wide: 122,538
• Since beginning of last month:
  • Site-wide: 97,811

Highly parallel genome variant engineering with CRISPR/Cas9 in eukaryotic cells

• Downloaded 1,788 times
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  • Site-wide: 7,702
  • In genomics: 877
• Year to date:
  • Site-wide: 107,644
• Since beginning of last month:
  • Site-wide: 74,199

Genetics of trans-regulatory variation in gene expression

• Downloaded 1,634 times
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  • Site-wide: 8,879
  • In genetics: 453
• Year to date:
  • Site-wide: 121,624
• Since beginning of last month:
  • Site-wide: 117,847

Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast

• Downloaded 1,391 times
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  • Site-wide: 11,287
  • In genetics: 576
• Year to date:
  • Site-wide: 73,230
• Since beginning of last month:
  • Site-wide: 85,909

Loss of flight in the Galapagos cormorant mirrors human skeletal ciliopathies

• Downloaded 1,373 times
• Download rankings, all-time:
  • Site-wide: 11,524
  • In genomics: 1,297
• Year to date:
  • Site-wide: 73,449
• Since beginning of last month:
  • Site-wide: 44,735

A maternal-effect genetic incompatibility in Caenorhabditis elegans

• Downloaded 1,355 times
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  • Site-wide: 11,759
  • In evolutionary biology: 437
• Year to date:
  • Site-wide: 103,976
• Since beginning of last month:
  • Site-wide: 115,171

Genetic Influences on Brain Gene Expression in Rats Selected for Tameness and Aggression

• Downloaded 1,352 times
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  • Site-wide: 11,801
  • In genomics: 1,325
• Year to date:
  • Site-wide: 104,331
• Since beginning of last month:
  • Site-wide: 81,868

Genetic interactions contribute less than additive effects to quantitative trait variation in yeast

• Downloaded 1,287 times
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  • Site-wide: 12,679
  • In genetics: 651
• Year to date:
  • Site-wide: 109,668
• Since beginning of last month:
  • Site-wide: 97,829

Genetic dissection of MAPK-mediated complex traits across S. cerevisiae

• Downloaded 1,273 times
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  • Site-wide: 12,876
  • In genetics: 662
• Year to date:
  • Site-wide: 85,836
• Since beginning of last month:
  • Site-wide: 116,395

Genetic influences on translation in yeast

• Downloaded 1,191 times
• Download rankings, all-time:
  • Site-wide: 14,257
  • In genetics: 743
• Year to date:
  • Site-wide: 85,960
• Since beginning of last month:
  • Site-wide: 48,562

Analysis of the genetic basis of height in large Jewish nuclear families

• Downloaded 1,046 times
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  • Site-wide: 17,317
  • In genetics: 891
• Year to date:
  • Site-wide: 35,893
• Since beginning of last month:
  • Site-wide: 20,592

Rare variants contribute disproportionately to quantitative trait variation in yeast

• Downloaded 983 times
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  • Site-wide: 19,015
  • In genetics: 968
• Year to date:
  • Site-wide: 46,947
• Since beginning of last month:
  • Site-wide: 105,090

The genetic basis of mutation rate variation in yeast

• Downloaded 954 times
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  • Site-wide: 19,854
  • In genetics: 998
• Year to date:
  • Site-wide: 19,767
• Since beginning of last month:
  • Site-wide: 18,879

Whole-organism eQTL mapping at cellular resolution with single-cell sequencing

• Downloaded 879 times
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  • Site-wide: 22,376
  • In genetics: 1,130
• Year to date:
  • Site-wide: 9,007
• Since beginning of last month:
  • Site-wide: 4,696

Rapid cost-effective viral genome sequencing by V-seq

• Downloaded 825 times
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  • Site-wide: 24,477
  • In genomics: 2,377
• Year to date:
  • Site-wide: 5,295
• Since beginning of last month:
  • Site-wide: 25,959

Full-genome evolutionary histories of selfing, splitting and selection in Caenorhabditis

• Downloaded 821 times
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  • Site-wide: 24,650
  • In genomics: 2,390
• Year to date:
  • Site-wide: 103,572
• Since beginning of last month:
  • Site-wide: 87,881

Genetics of intra-species variation in avoidance behavior induced by a thermal stimulus in C. elegans

• Downloaded 800 times
• Download rankings, all-time:
  • Site-wide: 25,540
  • In genetics: 1,288
• Year to date:
  • Site-wide: 119,047
• Since beginning of last month:
  • Site-wide: 81,427

Genetics of single-cell protein abundance variation in large yeast populations

• Downloaded 734 times
• Download rankings, all-time:
  • Site-wide: 28,816
  • In genomics: 2,669
• Year to date:
  • Site-wide: 108,044
• Since beginning of last month:
  • Site-wide: 107,931

Genetic Variation In Adaptability And Pleiotropy In Budding Yeast

• Downloaded 626 times
• Download rankings, all-time:
  • Site-wide: 35,631
  • In evolutionary biology: 1,874
• Year to date:
  • Site-wide: 120,839
• Since beginning of last month:
  • Site-wide: 121,396

Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk

• Downloaded 615 times
• Download rankings, all-time:
  • Site-wide: 36,435
  • In genetics: 1,809
• Year to date:
  • Site-wide: 106,696
• Since beginning of last month:
  • Site-wide: 105,420

Ubiquitous selfish toxin-antidote elements in Caenorhabditis species

• Downloaded 571 times
• Download rankings, all-time:
  • Site-wide: 39,990
  • In genomics: 3,361
• Year to date:
  • Site-wide: 13,029
• Since beginning of last month:
  • Site-wide: 22,001

Ancient balancing selection maintains incompatible versions of a conserved metabolic pathway in yeast

• Downloaded 552 times
• Download rankings, all-time:
  • Site-wide: 41,722
  • In evolutionary biology: 2,289
• Year to date:
  • Site-wide: 51,287
• Since beginning of last month:
  • Site-wide: 69,381

Genetics of white color and iridophoroma in "Lemon Frost" leopard geckos

• Downloaded 514 times
• Download rankings, all-time:
  • Site-wide: 45,551
  • In genetics: 2,212
• Year to date:
  • Site-wide: 1,032
• Since beginning of last month:
  • Site-wide: 877

Massively parallel identification of causal variants underlying gene expression differences in a yeast cross

• Downloaded 399 times
• Download rankings, all-time:
  • Site-wide: 59,990
  • In genetics: 2,880
• Year to date:
  • Site-wide: 21,969
• Since beginning of last month:
  • Site-wide: 77,265

Genomic epidemiology of the Los Angeles COVID-19 outbreak

• Downloaded 297 times
• Download rankings, all-time:
  • Site-wide: 77,391
  • In epidemiology: 3,137
• Year to date:
  • Site-wide: 28,519
• Since beginning of last month:
  • Site-wide: 25,892