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Author: Stephen R. Quake

Rankings

  • All-time downloads: 121,448 (rank: 689 )
  • Categories:
    • biochemistry: 247 (rank: 16,868 (tie) )
    • bioengineering: 2,086 (rank: 1,002 )
    • bioinformatics: 5,024 (rank: 2,176 (tie) )
    • biophysics: 508 (rank: 9,021 (tie) )
    • cancer biology: 3,189 (rank: 1,136 )
    • cell biology: 24,701 (rank: 4 )
    • developmental biology: 2,675 (rank: 721 )
    • genetics: 1,898 (rank: 9,005 (tie) )
    • genomics: 38,755 (rank: 191 )
    • immunology: 14,664 (rank: 429 )
    • microbiology: 7,080 (rank: 1,580 )
    • molecular biology: 419 (rank: 12,694 (tie) )
    • neuroscience: 18,353 (rank: 305 )
    • systems biology: 1,849 (rank: 2,053 (tie) )

Downloads per author, site-wide

Preprints

A molecular cell atlas of the human lung from single cell RNA sequencing

genomics more details view paper
  • Downloaded 17,619 times
  • Download rankings, all-time:
    • Site-wide: 339
    • In genomics: 17
  • Year to date:
    • Site-wide: 1,281
  • Since beginning of last month:
    • Site-wide: 742

Single-cell transcriptomic characterization of 20 organs and tissues from individual mice creates a Tabula Muris

cell biology more details view paper
  • Downloaded 13,094 times
  • Download rankings, all-time:
    • Site-wide: 468
    • In cell biology: 1
  • Year to date:
    • Site-wide: 47,016
  • Since beginning of last month:
    • Site-wide: 16,023

A Single Cell Transcriptomic Atlas Characterizes Aging Tissues in the Mouse

cell biology more details view paper
  • Downloaded 8,644 times
  • Download rankings, all-time:
    • Site-wide: 854
    • In cell biology: 9
  • Year to date:
    • Site-wide: 7,631
  • Since beginning of last month:
    • Site-wide: 3,440

c-Jun Overexpressing CAR-T Cells are Exhaustion-Resistant and Mediate Enhanced Antitumor Activity

immunology more details view paper
  • Downloaded 3,939 times
  • Download rankings, all-time:
    • Site-wide: 2,448
    • In immunology: 62
  • Year to date:
    • Site-wide: 8,151
  • Since beginning of last month:
    • Site-wide: 15,506

Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38+ pro-inflammatory macrophages

immunology more details view paper
  • Downloaded 3,320 times
  • Download rankings, all-time:
    • Site-wide: 3,167
    • In immunology: 81
  • Year to date:
    • Site-wide: 13,888
  • Since beginning of last month:
    • Site-wide: 4,511

The murine transcriptome reveals global aging nodes with organ-specific phase and amplitude

genomics more details view paper
  • Downloaded 3,230 times
  • Download rankings, all-time:
    • Site-wide: 3,304
    • In genomics: 390
  • Year to date:
    • Site-wide: 52,637
  • Since beginning of last month:
    • Site-wide: 23,088

Developmental heterogeneity of microglia and brain myeloid cells revealed by deep single-cell RNA sequencing

neuroscience more details view paper
  • Downloaded 3,102 times
  • Download rankings, all-time:
    • Site-wide: 3,514
    • In neuroscience: 294
  • Year to date:
    • Site-wide: 58,768
  • Since beginning of last month:
    • Site-wide: 47,651

Classifying Drosophila Olfactory Projection Neuron Subtypes by Single-cell RNA Sequencing

genomics more details view paper
  • Downloaded 2,866 times
  • Download rankings, all-time:
    • Site-wide: 3,882
    • In genomics: 459
  • Year to date:
    • Site-wide: 64,541
  • Since beginning of last month:
    • Site-wide: 85,305

Single cell profiling of total RNA using Smart-seq-total

genomics more details view paper
  • Downloaded 2,736 times
  • Download rankings, all-time:
    • Site-wide: 4,148
    • In genomics: 490
  • Year to date:
    • Site-wide: 2,424
  • Since beginning of last month:
    • Site-wide: 3,111

Pancreas patch-seq links physiologic dysfunction in diabetes to single-cell transcriptomic phenotypes

genomics more details view paper
  • Downloaded 2,529 times
  • Download rankings, all-time:
    • Site-wide: 4,668
    • In genomics: 557
  • Year to date:
    • Site-wide: 95,479
  • Since beginning of last month:
    • Site-wide: 30,686

Single cell RNAseq provides a molecular and cellular cartography of changes to the human endometrium through the menstrual cycle

genomics more details view paper
  • Downloaded 2,502 times
  • Download rankings, all-time:
    • Site-wide: 4,736
    • In genomics: 568
  • Year to date:
    • Site-wide: 15,429
  • Since beginning of last month:
    • Site-wide: 15,301

Serotonin Neurons in the Dorsal and Medial Raphe Nuclei: from Single-Cell Transcriptomes to Whole-Brain Projections

neuroscience more details view paper
  • Downloaded 2,300 times
  • Download rankings, all-time:
    • Site-wide: 5,406
    • In neuroscience: 523
  • Year to date:
    • Site-wide: 14,776
  • Since beginning of last month:
    • Site-wide: 21,348

Cell-Surface Proteomic Profiling in the Fly Brain Uncovers New Wiring Regulators

neuroscience more details view paper
  • Downloaded 2,193 times
  • Download rankings, all-time:
    • Site-wide: 5,789
    • In neuroscience: 568
  • Year to date:
    • Site-wide: 34,563
  • Since beginning of last month:
    • Site-wide: 45,117

Brain endothelial cells are exquisite sensors of age-related circulatory cues

neuroscience more details view paper
  • Downloaded 2,143 times
  • Download rankings, all-time:
    • Site-wide: 5,960
    • In neuroscience: 596
  • Year to date:
    • Site-wide: 15,549
  • Since beginning of last month:
    • Site-wide: 24,902

Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA

cancer biology more details view paper
  • Downloaded 2,041 times
  • Download rankings, all-time:
    • Site-wide: 6,409
    • In cancer biology: 104
  • Year to date:
    • Site-wide: 55,529
  • Since beginning of last month:
    • Site-wide: 28,659

A mouse tissue atlas of small non-coding RNA

genomics more details view paper
  • Downloaded 1,912 times
  • Download rankings, all-time:
    • Site-wide: 7,065
    • In genomics: 800
  • Year to date:
    • Site-wide: 19,264
  • Since beginning of last month:
    • Site-wide: 33,887

Nonivasive prenatal diagnosis of single-gene disorders using droplet digital PCR

genetics more details view paper
  • Downloaded 1,898 times
  • Download rankings, all-time:
    • Site-wide: 7,143
    • In genetics: 355
  • Year to date:
    • Site-wide: 37,291
  • Since beginning of last month:
    • Site-wide: 57,832

Single-cell analysis identifies EpCAM+/CDH6+/TROP-2- cells as human liver progenitors.

cell biology more details view paper
  • Downloaded 1,890 times
  • Download rankings, all-time:
    • Site-wide: 7,192
    • In cell biology: 164
  • Year to date:
    • Site-wide: 47,431
  • Since beginning of last month:
    • Site-wide: 32,366

Self-assembling Manifolds in Single-cell RNA Sequencing Data

bioinformatics more details view paper
  • Downloaded 1,882 times
  • Download rankings, all-time:
    • Site-wide: 7,232
    • In bioinformatics: 916
  • Year to date:
    • Site-wide: 78,675
  • Since beginning of last month:
    • Site-wide: 80,711

Single cell transcriptome analysis of human pancreas reveals transcriptional signatures of aging and somatic mutation patterns.

genomics more details view paper
  • Downloaded 1,878 times
  • Download rankings, all-time:
    • Site-wide: 7,252
    • In genomics: 819
  • Year to date:
    • Site-wide: 65,710
  • Since beginning of last month:
    • Site-wide: 82,186

Human IgE producing B cells have a unique transcriptional program and generate high affinity, allergen-specific antibodies

immunology more details view paper
  • Downloaded 1,872 times
  • Download rankings, all-time:
    • Site-wide: 7,291
    • In immunology: 192
  • Year to date:
    • Site-wide: 28,570
  • Since beginning of last month:
    • Site-wide: 18,575

Single-cell RNA-seq reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress

systems biology more details view paper
  • Downloaded 1,849 times
  • Download rankings, all-time:
    • Site-wide: 7,422
    • In systems biology: 135
  • Year to date:
    • Site-wide: 42,725
  • Since beginning of last month:
    • Site-wide: 62,994

Cerebellar nuclei evolved by repeatedly duplicating a conserved cell type set

neuroscience more details view paper
  • Downloaded 1,821 times
  • Download rankings, all-time:
    • Site-wide: 7,566
    • In neuroscience: 802
  • Year to date:
    • Site-wide: 4,906
  • Since beginning of last month:
    • Site-wide: 4,449

Differential encoding in prefrontal cortex projection neuron classes across cognitive tasks

neuroscience more details view paper
  • Downloaded 1,758 times
  • Download rankings, all-time:
    • Site-wide: 7,983
    • In neuroscience: 857
  • Year to date:
    • Site-wide: 6,446
  • Since beginning of last month:
    • Site-wide: 2,487

Humans are colonized by many uncharacterized and highly divergent microbes

microbiology more details view paper
  • Downloaded 1,573 times
  • Download rankings, all-time:
    • Site-wide: 9,494
    • In microbiology: 521
  • Year to date:
    • Site-wide: 97,750
  • Since beginning of last month:
    • Site-wide: 88,144

Microfluidic-based mini-metagenomics enables discovery of novel microbial lineages from complex environmental samples

microbiology more details view paper
  • Downloaded 1,486 times
  • Download rankings, all-time:
    • Site-wide: 10,309
    • In microbiology: 572
  • Year to date:
    • Site-wide: 122,488
  • Since beginning of last month:
    • Site-wide: 79,348

Single-cell transcriptional dynamics of flavivirus infection

microbiology more details view paper
  • Downloaded 1,384 times
  • Download rankings, all-time:
    • Site-wide: 11,470
    • In microbiology: 633
  • Year to date:
    • Site-wide: 75,514
  • Since beginning of last month:
    • Site-wide: 67,118

Discrete and Continuous Cell Identities of the Adult Murine Striatum

neuroscience more details view paper
  • Downloaded 1,337 times
  • Download rankings, all-time:
    • Site-wide: 12,081
    • In neuroscience: 1,435
  • Year to date:
    • Site-wide: 12,222
  • Since beginning of last month:
    • Site-wide: 30,285

Persistent transcriptional programs are associated with remote memory in diverse cells of the medial prefrontal cortex

neuroscience more details view paper
  • Downloaded 1,311 times
  • Download rankings, all-time:
    • Site-wide: 12,454
    • In neuroscience: 1,474
  • Year to date:
    • Site-wide: 20,924
  • Since beginning of last month:
    • Site-wide: 18,454

Coordinating Receptor Expression and Wiring Specificity in Olfactory Receptor Neurons

neuroscience more details view paper
  • Downloaded 1,301 times
  • Download rankings, all-time:
    • Site-wide: 12,590
    • In neuroscience: 1,489
  • Year to date:
    • Site-wide: 24,272
  • Since beginning of last month:
    • Site-wide: 27,711

Molecular hallmarks of heterochronic parabiosis at single cell resolution

genomics more details view paper
  • Downloaded 1,246 times
  • Download rankings, all-time:
    • Site-wide: 13,426
    • In genomics: 1,463
  • Year to date:
    • Site-wide: 2,214
  • Since beginning of last month:
    • Site-wide: 1,083

Transcriptional program of memory B cell activation, broadly binding anti-influenza antibodies, and bystander activation after vaccination revealed by single-cell transcriptomics

immunology more details view paper
  • Downloaded 1,237 times
  • Download rankings, all-time:
    • Site-wide: 13,583
    • In immunology: 364
  • Year to date:
    • Site-wide: 18,869
  • Since beginning of last month:
    • Site-wide: 24,497

Single-Cell RNAseq analysis of infiltrating neoplastic cells at the migrating front of human glioblastoma

cancer biology more details view paper
  • Downloaded 1,148 times
  • Download rankings, all-time:
    • Site-wide: 15,188
    • In cancer biology: 340
  • Year to date:
    • Site-wide: 31,702
  • Since beginning of last month:
    • Site-wide: 42,889

Signatures of Selection in the Human Antibody Repertoire: Selective Sweeps, Competing Subclones, and Neutral Drift

immunology more details view paper
  • Downloaded 1,069 times
  • Download rankings, all-time:
    • Site-wide: 16,946
    • In immunology: 454
  • Year to date:
    • Site-wide: 73,584
  • Since beginning of last month:
    • Site-wide: 83,611

5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages

genomics more details view paper
  • Downloaded 1,058 times
  • Download rankings, all-time:
    • Site-wide: 17,216
    • In genomics: 1,811
  • Year to date:
    • Site-wide: 87,156
  • Since beginning of last month:
    • Site-wide: 90,419

PhaMers identifies novel bacteriophage sequences from thermophilic hot springs

bioinformatics more details view paper
  • Downloaded 1,035 times
  • Download rankings, all-time:
    • Site-wide: 17,745
    • In bioinformatics: 2,178
  • Year to date:
    • Site-wide: 40,658
  • Since beginning of last month:
    • Site-wide: 103,741

Molecular and genetic regulation of pig pancreatic islet cell development

developmental biology more details view paper
  • Downloaded 1,006 times
  • Download rankings, all-time:
    • Site-wide: 18,564
    • In developmental biology: 329
  • Year to date:
    • Site-wide: 21,243
  • Since beginning of last month:
    • Site-wide: 28,011

Hydrogenotrophic methanogenesis in archaeal phylum Verstraetearchaeota reveals the shared ancestry of all methanogens

microbiology more details view paper
  • Downloaded 945 times
  • Download rankings, all-time:
    • Site-wide: 20,295
    • In microbiology: 1,147
  • Year to date:
    • Site-wide: 122,660
  • Since beginning of last month:
    • Site-wide: 62,001

Dynamics Of The Human Antibody Repertoire Following B-cell Depletion In Systemic Sclerosis

immunology more details view paper
  • Downloaded 924 times
  • Download rankings, all-time:
    • Site-wide: 20,965
    • In immunology: 564
  • Year to date:
    • Site-wide: 85,275
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    • Site-wide: 77,483

Virus-inclusive single cell RNA sequencing reveals molecular signature predictive of progression to severe dengue infection

immunology more details view paper
  • Downloaded 910 times
  • Download rankings, all-time:
    • Site-wide: 21,414
    • In immunology: 584
  • Year to date:
    • Site-wide: 68,042
  • Since beginning of last month:
    • Site-wide: 97,624

Evolutionary Origin of the Mammalian Hematopoietic System Found in a Colonial Chordate

immunology more details view paper
  • Downloaded 907 times
  • Download rankings, all-time:
    • Site-wide: 21,513
    • In immunology: 587
  • Year to date:
    • Site-wide: 99,312
  • Since beginning of last month:
    • Site-wide: 78,774

A single-parasite transcriptional atlas of Toxoplasma gondii reveals novel control of antigen expression

bioengineering more details view paper
  • Downloaded 898 times
  • Download rankings, all-time:
    • Site-wide: 21,856
    • In bioengineering: 370
  • Year to date:
    • Site-wide: 31,116
  • Since beginning of last month:
    • Site-wide: 44,343

Northstar enables automatic classification of known and novel cell types from tumor samples

bioinformatics more details view paper
  • Downloaded 827 times
  • Download rankings, all-time:
    • Site-wide: 24,597
    • In bioinformatics: 2,963
  • Year to date:
    • Site-wide: 39,914
  • Since beginning of last month:
    • Site-wide: 96,498

A Noninvasive Molecular Clock for Fetal Development Predicts Gestational Age and Preterm Delivery

bioengineering more details view paper
  • Downloaded 796 times
  • Download rankings, all-time:
    • Site-wide: 25,940
    • In bioengineering: 440
  • Year to date:
    • Site-wide: 65,258
  • Since beginning of last month:
    • Site-wide: 75,763

Mapping single-cell atlases throughout Metazoa unravels cell type evolution

bioinformatics more details view paper
  • Downloaded 779 times
  • Download rankings, all-time:
    • Site-wide: 26,743
    • In bioinformatics: 3,161
  • Year to date:
    • Site-wide: 4,986
  • Since beginning of last month:
    • Site-wide: 3,206

Nucleic Acid Cleavage with a Hyperthermophilic Cas9 from an Unculturable Ignavibacterium

genomics more details view paper
  • Downloaded 687 times
  • Download rankings, all-time:
    • Site-wide: 31,746
    • In genomics: 2,851
  • Year to date:
    • Site-wide: 44,658
  • Since beginning of last month:
    • Site-wide: 79,244

Diverse homeostatic and immunomodulatory roles of immune cells in the developing mouse lung revealed at single cell resolution

developmental biology more details view paper
  • Downloaded 668 times
  • Download rankings, all-time:
    • Site-wide: 32,964
    • In developmental biology: 721
  • Year to date:
    • Site-wide: 105,000
  • Since beginning of last month:
    • Site-wide: 28,683

Latrophilin-2 repels Teneurin-3+ hippocampal axons during target selection

neuroscience more details view paper
  • Downloaded 581 times
  • Download rankings, all-time:
    • Site-wide: 39,531
    • In neuroscience: 5,752
  • Year to date:
    • Site-wide: 37,428
  • Since beginning of last month:
    • Site-wide: 18,133

Single-cell transcriptional atlas of the Chinese horseshoe bat (Rhinolophus sinicus) provides insight into the cellular mechanisms which enable bats to be viral reservoirs

cell biology more details view paper
  • Downloaded 546 times
  • Download rankings, all-time:
    • Site-wide: 42,611
    • In cell biology: 1,803
  • Year to date:
    • Site-wide: 20,727
  • Since beginning of last month:
    • Site-wide: 32,097

Heterogeneous T cell motility behaviors emerge from a coupling between speed and turning in vivo

biophysics more details view paper
  • Downloaded 508 times
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    • Site-wide: 46,473
    • In biophysics: 1,580
  • Year to date:
    • Site-wide: 35,871
  • Since beginning of last month:
    • Site-wide: 64,589

Functional characterization and lineage analysis of broadly neutralizing human antibodies against dengue virus identified by single B cell transcriptomics

microbiology more details view paper
  • Downloaded 507 times
  • Download rankings, all-time:
    • Site-wide: 46,573
    • In microbiology: 2,932
  • Year to date:
    • Site-wide: 92,024
  • Since beginning of last month:
    • Site-wide: 47,894

Temporal evolution of single-cell transcriptomes of Drosophila olfactory projection neurons

neuroscience more details view paper
  • Downloaded 506 times
  • Download rankings, all-time:
    • Site-wide: 46,741
    • In neuroscience: 6,925
  • Year to date:
    • Site-wide: 13,635
  • Since beginning of last month:
    • Site-wide: 21,504

Modeling Spatial Correlation of Transcripts With Application to Developing Pancreas

bioinformatics more details view paper
  • Downloaded 501 times
  • Download rankings, all-time:
    • Site-wide: 47,301
    • In bioinformatics: 4,975
  • Year to date:
    • Site-wide: 88,049
  • Since beginning of last month:
    • Site-wide: 88,912

Molecular and Morphological Signatures of Chordate Development: Two Distinct Pathways, One Tunicate

developmental biology more details view paper
  • Downloaded 498 times
  • Download rankings, all-time:
    • Site-wide: 47,624
    • In developmental biology: 1,149
  • Year to date:
    • Site-wide: 91,170
  • Since beginning of last month:
    • Site-wide: 65,155

Viral Taxonomy Derived From Evolutionary Genome Relationships

genomics more details view paper
  • Downloaded 492 times
  • Download rankings, all-time:
    • Site-wide: 48,254
    • In genomics: 3,855
  • Year to date:
    • Site-wide: 97,371
  • Since beginning of last month:
    • Site-wide: 63,203

Matrix-corrected mass spectrometry enables sensitive detection of food allergens and reveals widespread soy contamination of processed foods

immunology more details view paper
  • Downloaded 486 times
  • Download rankings, all-time:
    • Site-wide: 48,915
    • In immunology: 1,300
  • Year to date:
    • Site-wide: 104,595
  • Since beginning of last month:
    • Site-wide: 66,753

The transcriptional landscape of Venezuelan equine encephalitis virus (TC-83) infection

microbiology more details view paper
  • Downloaded 461 times
  • Download rankings, all-time:
    • Site-wide: 52,058
    • In microbiology: 3,357
  • Year to date:
    • Site-wide: 32,865
  • Since beginning of last month:
    • Site-wide: 34,246

Single-cell analysis of Schistosoma mansoni reveals a conserved genetic program controlling germline stem cell fate

developmental biology more details view paper
  • Downloaded 436 times
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    • Site-wide: 55,201
    • In developmental biology: 1,395
  • Year to date:
    • Site-wide: 13,327
  • Since beginning of last month:
    • Site-wide: 16,840

Non-invasive characterization of human bone marrow by cell free messenger-RNA reveals response to growth factor stimulation and hematopoietic reconstitution after transplantation

molecular biology more details view paper
  • Downloaded 419 times
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    • Site-wide: 57,576
    • In molecular biology: 1,655
  • Year to date:
    • Site-wide: 99,408
  • Since beginning of last month:
    • Site-wide: 117,797

An inexpensive semi-automated sample processing pipeline for cell-free RNA

bioengineering more details view paper
  • Downloaded 392 times
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    • Site-wide: 61,428
    • In bioengineering: 1,121
  • Year to date:
    • Site-wide: 17,757
  • Since beginning of last month:
    • Site-wide: 14,783

Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite Toxoplasma gondii

microbiology more details view paper
  • Downloaded 367 times
  • Download rankings, all-time:
    • Site-wide: 65,412
    • In microbiology: 4,429
  • Year to date:
    • Site-wide: 65,655
  • Since beginning of last month:
    • Site-wide: 83,113

Cell-free DNA Reveals Potential Zoonotic Reservoirs in Non-Human Primates

microbiology more details view paper
  • Downloaded 357 times
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    • Site-wide: 67,056
    • In microbiology: 4,577
  • Year to date:
    • Site-wide: 76,636
  • Since beginning of last month:
    • Site-wide: 59,031

NFIA regulates granule recruitment and exocytosis in the adult pancreas

cell biology more details view paper
  • Downloaded 336 times
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    • Site-wide: 70,824
    • In cell biology: 3,226
  • Year to date:
    • Site-wide: 52,931
  • Since beginning of last month:
    • Site-wide: 66,544

Kinetics and Fidelity of Psychrophilic DNA Polymerases

biochemistry more details view paper
  • Downloaded 247 times
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    • Site-wide: 88,155
    • In biochemistry: 2,576
  • Year to date:
    • Site-wide: 29,125
  • Since beginning of last month:
    • Site-wide: 29,991

Single-cell RNA Expression of SARS-CoV-2 Cell Entry Factors in Human Endometrium during Preconception

cell biology more details view paper
  • Downloaded 191 times
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    • Site-wide: 100,128
    • In cell biology: 4,652
  • Year to date:
    • Site-wide: 63,706
  • Since beginning of last month:
    • Site-wide: 59,016

Global Age-Specific Patterns of Cyclic Gene Expression Revealed by Tunicate Transcriptome Atlas

developmental biology more details view paper
  • Downloaded 67 times
  • Download rankings, all-time:
    • Site-wide: 121,824
    • In developmental biology: 3,223
  • Year to date:
    • Site-wide: 77,314
  • Since beginning of last month:
    • Site-wide: 10,632

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