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Author: Stephen R. Quake

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    • bioengineering: 1,582 (rank: 1,193 out of 12,052)
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    • biophysics: 447 (rank: 8,288 (tie) out of 16,811)
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    • cell biology: 23,176 (rank: 3 out of 30,511)
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    • genetics: 1,817 (rank: 8,393 (tie) out of 36,792)
    • genomics: 31,917 (rank: 239 out of 42,763)
    • immunology: 13,192 (rank: 296 out of 23,479)
    • microbiology: 6,603 (rank: 1,183 out of 46,811)
    • molecular biology: 395 (rank: 10,588 (tie) out of 21,566)
    • neuroscience: 15,256 (rank: 331 out of 67,824)
    • systems biology: 1,797 (rank: 1,749 (tie) out of 11,761)

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Preprints

An inexpensive semi-automated sample processing pipeline for cell-free RNA

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A molecular cell atlas of the human lung from single cell RNA sequencing

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Single-cell transcriptomic characterization of 20 organs and tissues from individual mice creates a Tabula Muris

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A Single Cell Transcriptomic Atlas Characterizes Aging Tissues in the Mouse

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c-Jun Overexpressing CAR-T Cells are Exhaustion-Resistant and Mediate Enhanced Antitumor Activity

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Developmental heterogeneity of microglia and brain myeloid cells revealed by deep single-cell RNA sequencing

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The murine transcriptome reveals global aging nodes with organ-specific phase and amplitude

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Classifying Drosophila Olfactory Projection Neuron Subtypes by Single-cell RNA Sequencing

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Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38+ pro-inflammatory macrophages

immunology more details view paper
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Pancreas patch-seq links physiologic dysfunction in diabetes to single-cell transcriptomic phenotypes

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Single cell RNAseq provides a molecular and cellular cartography of changes to the human endometrium through the menstrual cycle

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Serotonin Neurons in the Dorsal and Medial Raphe Nuclei: from Single-Cell Transcriptomes to Whole-Brain Projections

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Cell-Surface Proteomic Profiling in the Fly Brain Uncovers New Wiring Regulators

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Brain endothelial cells are exquisite sensors of age-related circulatory cues

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Single cell profiling of total RNA using Smart-seq-total

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Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA

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Single cell transcriptome analysis of human pancreas reveals transcriptional signatures of aging and somatic mutation patterns.

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Self-assembling Manifolds in Single-cell RNA Sequencing Data

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Nonivasive prenatal diagnosis of single-gene disorders using droplet digital PCR

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Single-cell RNA-seq reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress

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Single-cell analysis identifies EpCAM+/CDH6+/TROP-2- cells as human liver progenitors.

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Human IgE producing B cells have a unique transcriptional program and generate high affinity, allergen-specific antibodies

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A mouse tissue atlas of small non-coding RNA

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Humans are colonized by many uncharacterized and highly divergent microbes

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Microfluidic-based mini-metagenomics enables discovery of novel microbial lineages from complex environmental samples

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Single-cell transcriptional dynamics of flavivirus infection

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Cerebellar nuclei evolved by repeatedly duplicating a conserved cell type set

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Coordinating Receptor Expression and Wiring Specificity in Olfactory Receptor Neurons

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Discrete and Continuous Cell Identities of the Adult Murine Striatum

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Single-Cell RNAseq analysis of infiltrating neoplastic cells at the migrating front of human glioblastoma

cancer biology more details view paper
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Transcriptional program of memory B cell activation, broadly binding anti-influenza antibodies, and bystander activation after vaccination revealed by single-cell transcriptomics

immunology more details view paper
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Signatures of Selection in the Human Antibody Repertoire: Selective Sweeps, Competing Subclones, and Neutral Drift

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Differential encoding in prefrontal cortex projection neuron classes across cognitive tasks

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5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages

genomics more details view paper
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Persistent transcriptional programs are associated with remote memory in diverse cells of the medial prefrontal cortex

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PhaMers identifies novel bacteriophage sequences from thermophilic hot springs

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Hydrogenotrophic methanogenesis in archaeal phylum Verstraetearchaeota reveals the shared ancestry of all methanogens

microbiology more details view paper
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Dynamics Of The Human Antibody Repertoire Following B-cell Depletion In Systemic Sclerosis

immunology more details view paper
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Virus-inclusive single cell RNA sequencing reveals molecular signature predictive of progression to severe dengue infection

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Molecular and genetic regulation of pig pancreatic islet cell development

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Evolutionary Origin of the Mammalian Hematopoietic System Found in a Colonial Chordate

immunology more details view paper
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A single-parasite transcriptional atlas of Toxoplasma gondii reveals novel control of antigen expression

bioengineering more details view paper
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A Noninvasive Molecular Clock for Fetal Development Predicts Gestational Age and Preterm Delivery

bioengineering more details view paper
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Northstar enables automatic classification of known and novel cell types from tumor samples

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Nucleic Acid Cleavage with a Hyperthermophilic Cas9 from an Unculturable Ignavibacterium

genomics more details view paper
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Diverse homeostatic and immunomodulatory roles of immune cells in the developing mouse lung revealed at single cell resolution

developmental biology more details view paper
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Viral Taxonomy Derived From Evolutionary Genome Relationships

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Modeling Spatial Correlation of Transcripts With Application to Developing Pancreas

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Matrix-corrected mass spectrometry enables sensitive detection of food allergens and reveals widespread soy contamination of processed foods

immunology more details view paper
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Heterogeneous T cell motility behaviors emerge from a coupling between speed and turning in vivo

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Molecular and Morphological Signatures of Chordate Development: Two Distinct Pathways, One Tunicate

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Functional characterization and lineage analysis of broadly neutralizing human antibodies against dengue virus identified by single B cell transcriptomics

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Non-invasive characterization of human bone marrow by cell free messenger-RNA reveals response to growth factor stimulation and hematopoietic reconstitution after transplantation

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Latrophilin-2 repels Teneurin-3+ hippocampal axons during target selection

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Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite Toxoplasma gondii

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The transcriptional landscape of Venezuelan equine encephalitis virus (TC-83) infection

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Cell-free DNA Reveals Potential Zoonotic Reservoirs in Non-Human Primates

microbiology more details view paper
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NFIA regulates granule recruitment and exocytosis in the adult pancreas

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Single-cell transcriptional atlas of the Chinese horseshoe bat (Rhinolophus sinicus) provides insight into the cellular mechanisms which enable bats to be viral reservoirs

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Single-cell analysis of Schistosoma mansoni reveals a conserved genetic program controlling germline stem cell fate

developmental biology more details view paper
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Kinetics and Fidelity of Psychrophilic DNA Polymerases

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