Author: Marcella Rietschel

Downloads per author, site-wide

Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

• Downloaded 9,392 times
• Download rankings, all-time:
  • Site-wide: 870
  • In genetics: 26
• Year to date:
  • Site-wide: 31,379
• Since beginning of last month:
  • Site-wide: 33,428

The genetic architecture of the human cerebral cortex

• Downloaded 8,006 times
• Download rankings, all-time:
  • Site-wide: 1,068
  • In genetics: 31
• Year to date:
  • Site-wide: 13,321
• Since beginning of last month:
  • Site-wide: 23,948

Genomewide association study identifies 30 loci associated with bipolar disorder

• Downloaded 7,323 times
• Download rankings, all-time:
  • Site-wide: 1,202
  • In genetics: 38
• Year to date:
  • Site-wide: 18,472
• Since beginning of last month:
  • Site-wide: 18,112

DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning

• Downloaded 4,285 times
• Download rankings, all-time:
  • Site-wide: 2,473
  • In systems biology: 32
• Year to date:
  • Site-wide: 59,441
• Since beginning of last month:
  • Site-wide: 56,552

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

• Downloaded 2,120 times
• Download rankings, all-time:
  • Site-wide: 6,861
  • In psychiatry and clinical psychology: 23
• Year to date:
  • Site-wide: 1,382
• Since beginning of last month:
  • Site-wide: 772

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

• Downloaded 1,884 times
• Download rankings, all-time:
  • Site-wide: 8,176
  • In genetics: 376
• Year to date:
  • Site-wide: 65,792
• Since beginning of last month:
  • Site-wide: 61,434

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

• Downloaded 1,791 times
• Download rankings, all-time:
  • Site-wide: 8,817
  • In genetics: 414
• Year to date:
  • Site-wide: 47,908
• Since beginning of last month:
  • Site-wide: 56,252

Dynamics of Brain Structure and its Genetic Architecture over the Lifespan

• Downloaded 1,782 times
• Download rankings, all-time:
  • Site-wide: 8,893
  • In genetics: 423
• Year to date:
  • Site-wide: 12,951
• Since beginning of last month:
  • Site-wide: 16,572

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

• Downloaded 1,717 times
• Download rankings, all-time:
  • Site-wide: 9,415
  • In genetics: 450
• Year to date:
  • Site-wide: 84,041
• Since beginning of last month:
  • Site-wide: 89,315

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

• Downloaded 1,497 times
• Download rankings, all-time:
  • Site-wide: 11,449
  • In genetics: 552
• Year to date:
  • Site-wide: 17,494
• Since beginning of last month:
  • Site-wide: 20,737

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,458 times
• Download rankings, all-time:
  • Site-wide: 11,925
  • In genomics: 1,296
• Year to date:
  • Site-wide: 74,651
• Since beginning of last month:
  • Site-wide: 75,484

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

• Downloaded 1,296 times
• Download rankings, all-time:
  • Site-wide: 14,308
  • In genetics: 705
• Year to date:
  • Site-wide: 101,902
• Since beginning of last month:
  • Site-wide: 111,820

Genomic architecture of human neuroanatomical diversity

• Downloaded 1,158 times
• Download rankings, all-time:
  • Site-wide: 16,936
  • In neuroscience: 2,101
• Year to date:
  • Site-wide: 98,482
• Since beginning of last month:
  • Site-wide: 109,981

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

• Downloaded 1,070 times
• Download rankings, all-time:
  • Site-wide: 19,018
  • In genetics: 924
• Year to date:
  • Site-wide: 3,734
• Since beginning of last month:
  • Site-wide: 3,712

Pharmacogenetics of antidepressant response: a polygenic approach

• Downloaded 895 times
• Download rankings, all-time:
  • Site-wide: 24,664
  • In genetics: 1,191
• Year to date:
  • Site-wide: 79,830
• Since beginning of last month:
  • Site-wide: 78,256

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 843 times
• Download rankings, all-time:
  • Site-wide: 26,778
  • In genetics: 1,293
• Year to date:
  • Site-wide: 77,709
• Since beginning of last month:
  • Site-wide: 74,201

Cross-validation of technologies for genotyping CYP2D6 and CYP2C19

• Downloaded 813 times
• Download rankings, all-time:
  • Site-wide: 28,187
  • In genetics: 1,369
• Year to date:
  • Site-wide: 20,315
• Since beginning of last month:
  • Site-wide: 26,188

Polygenic scores for major depressive disorder and depressive symptoms predict response to lithium in patients with bipolar disorder

• Downloaded 796 times
• Download rankings, all-time:
  • Site-wide: 29,021
  • In genomics: 2,659
• Year to date:
  • Site-wide: 72,247
• Since beginning of last month:
  • Site-wide: 60,504

Planar cell polarity pathway and development of the human visual cortex

• Downloaded 769 times
• Download rankings, all-time:
  • Site-wide: 30,473
  • In neuroscience: 4,125
• Year to date:
  • Site-wide: 61,284
• Since beginning of last month:
  • Site-wide: 73,518

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

• Downloaded 733 times
• Download rankings, all-time:
  • Site-wide: 32,629
  • In genetics: 1,580
• Year to date:
  • Site-wide: 12,356
• Since beginning of last month:
  • Site-wide: 8,423

Generative network models identify biological mechanisms of altered structural brain connectivity in schizophrenia

• Downloaded 718 times
• Download rankings, all-time:
  • Site-wide: 33,508
  • In neuroscience: 4,615
• Year to date:
  • Site-wide: 74,464
• Since beginning of last month:
  • Site-wide: 53,719

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

• Downloaded 711 times
• Download rankings, all-time:
  • Site-wide: 33,922
  • In genetics: 1,641
• Year to date:
  • Site-wide: 79,770
• Since beginning of last month:
  • Site-wide: 71,916

Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

• Downloaded 685 times
• Download rankings, all-time:
  • Site-wide: 35,700
  • In neurology: 64
• Year to date:
  • Site-wide: 1,913
• Since beginning of last month:
  • Site-wide: 553

Higher genetic risk for schizophrenia is associated with living in urban and populated areas

• Downloaded 655 times
• Download rankings, all-time:
  • Site-wide: 37,922
  • In genetics: 1,806
• Year to date:
  • Site-wide: 93,226
• Since beginning of last month:
  • Site-wide: 75,051

Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depression

• Downloaded 611 times
• Download rankings, all-time:
  • Site-wide: 41,423
  • In neuroscience: 5,905
• Year to date:
  • Site-wide: 75,178
• Since beginning of last month:
  • Site-wide: 67,043

New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

• Downloaded 589 times
• Download rankings, all-time:
  • Site-wide: 43,372
  • In genomics: 3,531
• Year to date:
  • Site-wide: 124,700
• Since beginning of last month:
  • Site-wide: 112,442

High genetic loading for schizophrenia predicts poor response to lithium in patients with bipolar disorder: A polygenic score and cross-trait genetic analysis

• Downloaded 571 times
• Download rankings, all-time:
  • Site-wide: 45,049
  • In genetics: 2,122
• Year to date:
  • Site-wide: 110,873
• Since beginning of last month:
  • Site-wide: 89,300

Expanding the Genetic Architecture of Nicotine Dependence and its Shared Genetics with Multiple Traits: Findings from the Nicotine Dependence GenOmics (iNDiGO) Consortium

• Downloaded 569 times
• Download rankings, all-time:
  • Site-wide: 45,234
  • In genomics: 3,633
• Year to date:
  • Site-wide: 53,645
• Since beginning of last month:
  • Site-wide: 50,066

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

• Downloaded 524 times
• Download rankings, all-time:
  • Site-wide: 49,991
  • In genetics: 2,334
• Year to date:
  • Site-wide: 110,831
• Since beginning of last month:
  • Site-wide: 107,830

Genotype-phenotype association mining in bipolar disorder: market research meets complex genetics

• Downloaded 503 times
• Download rankings, all-time:
  • Site-wide: 52,460
  • In genomics: 4,068
• Year to date:
  • Site-wide: 110,546
• Since beginning of last month:
  • Site-wide: 112,450

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

• Downloaded 491 times
• Download rankings, all-time:
  • Site-wide: 53,954
  • In genetics: 2,503
• Year to date:
  • Site-wide: 128,291
• Since beginning of last month:
  • Site-wide: 105,147

Longitudinal transcriptome-wide gene expression analysis of sleep deprivation treatment shows involvement of circadian genes and immune pathways

• Downloaded 432 times
• Download rankings, all-time:
  • Site-wide: 61,788
  • In epidemiology: 2,665
• Year to date:
  • Site-wide: 105,888
• Since beginning of last month:
  • Site-wide: 97,433

Response to Therapeutic Sleep Deprivation: A Naturalistic Study of Clinical and Genetic Factors and Post-Treatment Depressive Symptom Trajectory

• Downloaded 341 times
• Download rankings, all-time:
  • Site-wide: 77,090
  • In epidemiology: 3,207
• Year to date:
  • Site-wide: 126,901
• Since beginning of last month:
  • Site-wide: 98,781

Exemplar Scoring Identifies Genetically Separable Phenotypes of Lithium Responsive Bipolar Disorder

• Downloaded 255 times
• Download rankings, all-time:
  • Site-wide: 95,031
  • In psychiatry and clinical psychology: 348
• Year to date:
  • Site-wide: 66,238
• Since beginning of last month:
  • Site-wide: 54,355

"The Heidelberg Five" Personality Dimensions: Genome-wide Associations, Polygenic Risk for Neuroticism, and Psychopathology 20 Years after Assessment

• Downloaded 194 times
• Download rankings, all-time:
  • Site-wide: 108,493
  • In genomics: 6,241
• Year to date:
  • Site-wide: 84,213
• Since beginning of last month:
  • Site-wide: 103,759

Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning

• Downloaded 137 times
• Download rankings, all-time:
  • Site-wide: 120,485
  • In psychiatry and clinical psychology: 550
• Year to date:
  • Site-wide: 17,890
• Since beginning of last month:
  • Site-wide: 26,513

Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression

• Downloaded 134 times
• Download rankings, all-time:
  • Site-wide: 121,096
  • In psychiatry and clinical psychology: 554
• Year to date:
  • Site-wide: 18,437
• Since beginning of last month:
  • Site-wide: 10,619

Genetic Contributions to Alcohol Use Disorder Treatment Outcomes: A Genome-wide Pharmacogenomics Study

• Downloaded 105 times
• Download rankings, all-time:
  • Site-wide: 126,504
  • In genetic and genomic medicine: 614
• Year to date:
  • Site-wide: 24,545
• Since beginning of last month:
  • Site-wide: 22,752

Connection Failure: Differences in White Matter Microstructure are associated with 5-HTTLPR but not with Risk-Seeking for Losses

• Downloaded 32 times
• Download rankings, all-time:
  • Site-wide: 134,425
  • In neuroscience: 20,555
• Year to date:
  • Site-wide: 74,189
• Since beginning of last month:
  • Site-wide: 51,834