Author: Marcella D.C. Rietschel

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 750
  • In genetics: 24
• Year to date:
  • Site-wide: 17,640
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  • Site-wide: 21,538

The genetic architecture of the human cerebral cortex

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  • Site-wide: 942
  • In genetics: 30
• Year to date:
  • Site-wide: 9,162
• Since beginning of last month:
  • Site-wide: 12,902

Genomewide association study identifies 30 loci associated with bipolar disorder

• Downloaded 7,200 times
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  • Site-wide: 1,064
  • In genetics: 38
• Year to date:
  • Site-wide: 25,475
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  • Site-wide: 20,016

DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning

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  • Site-wide: 2,169
  • In systems biology: 30
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 93,531

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

• Downloaded 1,856 times
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  • Site-wide: 7,267
  • In genetics: 361
• Year to date:
  • Site-wide: 33,469
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  • Site-wide: 51,117

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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  • Site-wide: 7,874
  • In genetics: 396
• Year to date:
  • Site-wide: 12,473
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  • Site-wide: 37,254

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

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  • Site-wide: 8,334
  • In genetics: 423
• Year to date:
  • Site-wide: 72,018
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  • Site-wide: 54,505

Dynamics of Brain Structure and its Genetic Architecture over the Lifespan

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  • Site-wide: 9,206
  • In genetics: 476
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  • Site-wide: None
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  • Site-wide: 63,405

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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  • Site-wide: 10,736
  • In genomics: 1,223
• Year to date:
  • Site-wide: 54,173
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  • Site-wide: 96,498

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

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  • Site-wide: 11,616
  • In genetics: 601
• Year to date:
  • Site-wide: 93,686
• Since beginning of last month:
  • Site-wide: 18,280

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

• Downloaded 1,281 times
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  • Site-wide: 12,675
  • In genetics: 654
• Year to date:
  • Site-wide: 60,716
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  • Site-wide: 66,984

Genomic architecture of human neuroanatomical diversity

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  • Site-wide: 15,117
  • In neuroscience: 1,904
• Year to date:
  • Site-wide: 66,528
• Since beginning of last month:
  • Site-wide: 112,523

Pharmacogenetics of antidepressant response: a polygenic approach

• Downloaded 876 times
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  • Site-wide: 22,319
  • In genetics: 1,130
• Year to date:
  • Site-wide: 28,947
• Since beginning of last month:
  • Site-wide: 73,906

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 817 times
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  • Site-wide: 24,676
  • In genetics: 1,248
• Year to date:
  • Site-wide: 68,879
• Since beginning of last month:
  • Site-wide: 59,628

Polygenic scores for major depressive disorder and depressive symptoms predict response to lithium in patients with bipolar disorder

• Downloaded 769 times
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  • Site-wide: 26,821
  • In genomics: 2,552
• Year to date:
  • Site-wide: 49,836
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  • Site-wide: 69,962

Planar cell polarity pathway and development of the human visual cortex

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  • Site-wide: 28,479
  • In neuroscience: 3,947
• Year to date:
  • Site-wide: 32,109
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  • Site-wide: 43,825

Cross-validation of technologies for genotyping CYP2D6 and CYP2C19

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  • Site-wide: 30,721
  • In genetics: 1,555
• Year to date:
  • Site-wide: 38,077
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  • Site-wide: 11,458

Generative network models identify biological mechanisms of altered structural brain connectivity in schizophrenia

• Downloaded 691 times
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  • Site-wide: 31,055
  • In neuroscience: 4,375
• Year to date:
  • Site-wide: 53,973
• Since beginning of last month:
  • Site-wide: 61,391

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

• Downloaded 688 times
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  • Site-wide: 31,222
  • In genetics: 1,578
• Year to date:
  • Site-wide: 48,466
• Since beginning of last month:
  • Site-wide: 98,513

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

• Downloaded 675 times
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  • Site-wide: 32,091
  • In genetics: 1,618
• Year to date:
  • Site-wide: 8,028
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  • Site-wide: 9,107

Higher genetic risk for schizophrenia is associated with living in urban and populated areas

• Downloaded 636 times
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  • Site-wide: 34,674
  • In genetics: 1,738
• Year to date:
  • Site-wide: 67,631
• Since beginning of last month:
  • Site-wide: 97,186

New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

• Downloaded 582 times
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  • Site-wide: 38,818
  • In genomics: 3,302
• Year to date:
  • Site-wide: 54,279
• Since beginning of last month:
  • Site-wide: 98,506

Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depression

• Downloaded 580 times
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  • Site-wide: 38,964
  • In neuroscience: 5,683
• Year to date:
  • Site-wide: 105,351
• Since beginning of last month:
  • Site-wide: 90,749

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

• Downloaded 560 times
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  • Site-wide: 40,742
  • In genetics: 2,002
• Year to date:
  • Site-wide: 29,305
• Since beginning of last month:
  • Site-wide: 75,007

High genetic loading for schizophrenia predicts poor response to lithium in patients with bipolar disorder: A polygenic score and cross-trait genetic analysis

• Downloaded 557 times
• Download rankings, all-time:
  • Site-wide: 40,950
  • In genetics: 2,020
• Year to date:
  • Site-wide: 73,852
• Since beginning of last month:
  • Site-wide: 44,022

Expanding the Genetic Architecture of Nicotine Dependence and its Shared Genetics with Multiple Traits: Findings from the Nicotine Dependence GenOmics (iNDiGO) Consortium

• Downloaded 530 times
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  • Site-wide: 43,595
  • In genomics: 3,592
• Year to date:
  • Site-wide: 33,233
• Since beginning of last month:
  • Site-wide: 66,817

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

• Downloaded 513 times
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  • Site-wide: 45,305
  • In genetics: 2,212
• Year to date:
  • Site-wide: 49,562
• Since beginning of last month:
  • Site-wide: 102,542

Genotype-phenotype association mining in bipolar disorder: market research meets complex genetics

• Downloaded 489 times
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  • Site-wide: 47,953
  • In genomics: 3,842
• Year to date:
  • Site-wide: 82,738
• Since beginning of last month:
  • Site-wide: 107,374

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

• Downloaded 482 times
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  • Site-wide: 48,699
  • In genetics: 2,374
• Year to date:
  • Site-wide: 101,728
• Since beginning of last month:
  • Site-wide: 93,025

Longitudinal transcriptome-wide gene expression analysis of sleep deprivation treatment shows involvement of circadian genes and immune pathways

• Downloaded 418 times
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  • Site-wide: 56,873
  • In epidemiology: 2,378
• Year to date:
  • Site-wide: 62,365
• Since beginning of last month:
  • Site-wide: 63,018

Response to Therapeutic Sleep Deprivation: A Naturalistic Study of Clinical and Genetic Factors and Post-Treatment Depressive Symptom Trajectory

• Downloaded 330 times
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  • Site-wide: 70,798
  • In epidemiology: 2,884
• Year to date:
  • Site-wide: 103,598
• Since beginning of last month:
  • Site-wide: 118,436

Exemplar Scoring Identifies Genetically Separable Phenotypes of Lithium Responsive Bipolar Disorder

• Downloaded 219 times
• Download rankings, all-time:
  • Site-wide: 92,761
  • In psychiatry and clinical psychology: 320
• Year to date:
  • Site-wide: 96,115
• Since beginning of last month:
  • Site-wide: 49,429

"The Heidelberg Five" Personality Dimensions: Genome-wide Associations, Polygenic Risk for Neuroticism, and Psychopathology 20 Years after Assessment

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• Download rankings, all-time:
  • Site-wide: 104,439
  • In genomics: 6,070
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 105,510