Author: Marcella Rietschel

Downloads per author, site-wide

Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

• Downloaded 9,242 times
• Download rankings, all-time:
  • Site-wide: 317 out of 100,883
  • In genetics: 24 out of 5,020
• Year to date:
  • Site-wide: 11,817 out of 100,883
• Since beginning of last month:
  • Site-wide: 8,612 out of 100,883

The genetic architecture of the human cerebral cortex

• Downloaded 7,678 times
• Download rankings, all-time:
  • Site-wide: 429 out of 100,883
  • In genetics: 28 out of 5,020
• Year to date:
  • Site-wide: 1,978 out of 100,883
• Since beginning of last month:
  • Site-wide: 9,623 out of 100,883

Genomewide association study identifies 30 loci associated with bipolar disorder

• Downloaded 7,099 times
• Download rankings, all-time:
  • Site-wide: 490 out of 100,883
  • In genetics: 37 out of 5,020
• Year to date:
  • Site-wide: 5,316 out of 100,883
• Since beginning of last month:
  • Site-wide: 7,497 out of 100,883

DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning

• Downloaded 4,201 times
• Download rankings, all-time:
  • Site-wide: 1,205 out of 100,883
  • In systems biology: 29 out of 2,563
• Year to date:
  • Site-wide: 19,924 out of 100,883
• Since beginning of last month:
  • Site-wide: 32,897 out of 100,883

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

• Downloaded 1,810 times
• Download rankings, all-time:
  • Site-wide: 4,990 out of 100,883
  • In genetics: 353 out of 5,020
• Year to date:
  • Site-wide: 31,412 out of 100,883
• Since beginning of last month:
  • Site-wide: 46,740 out of 100,883

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

• Downloaded 1,706 times
• Download rankings, all-time:
  • Site-wide: 5,473 out of 100,883
  • In genetics: 385 out of 5,020
• Year to date:
  • Site-wide: 71,492 out of 100,883
• Since beginning of last month:
  • Site-wide: 83,495 out of 100,883

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

• Downloaded 1,661 times
• Download rankings, all-time:
  • Site-wide: 5,716 out of 100,883
  • In genetics: 405 out of 5,020
• Year to date:
  • Site-wide: 49,446 out of 100,883
• Since beginning of last month:
  • Site-wide: 63,575 out of 100,883

Dynamics of Brain Structure and its Genetic Architecture over the Lifespan

• Downloaded 1,522 times
• Download rankings, all-time:
  • Site-wide: 6,661 out of 100,883
  • In genetics: 469 out of 5,020
• Year to date:
  • Site-wide: 1,358 out of 100,883
• Since beginning of last month:
  • Site-wide: 6,684 out of 100,883

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,414 times
• Download rankings, all-time:
  • Site-wide: 7,542 out of 100,883
  • In genomics: 1,147 out of 6,254
• Year to date:
  • Site-wide: 64,277 out of 100,883
• Since beginning of last month:
  • Site-wide: 65,585 out of 100,883

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

• Downloaded 1,257 times
• Download rankings, all-time:
  • Site-wide: 9,221 out of 100,883
  • In genetics: 624 out of 5,020
• Year to date:
  • Site-wide: 5,309 out of 100,883
• Since beginning of last month:
  • Site-wide: 6,199 out of 100,883

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

• Downloaded 1,256 times
• Download rankings, all-time:
  • Site-wide: 9,231 out of 100,883
  • In genetics: 625 out of 5,020
• Year to date:
  • Site-wide: 75,429 out of 100,883
• Since beginning of last month:
  • Site-wide: 63,887 out of 100,883

Genomic architecture of human neuroanatomical diversity

• Downloaded 1,130 times
• Download rankings, all-time:
  • Site-wide: 11,026 out of 100,883
  • In neuroscience: 1,727 out of 17,976
• Year to date:
  • Site-wide: 92,092 out of 100,883
• Since beginning of last month:
  • Site-wide: 82,125 out of 100,883

Pharmacogenetics of antidepressant response: a polygenic approach

• Downloaded 835 times
• Download rankings, all-time:
  • Site-wide: 17,804 out of 100,883
  • In genetics: 1,109 out of 5,020
• Year to date:
  • Site-wide: 46,001 out of 100,883
• Since beginning of last month:
  • Site-wide: 34,561 out of 100,883

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 792 times
• Download rankings, all-time:
  • Site-wide: 19,381 out of 100,883
  • In genetics: 1,207 out of 5,020
• Year to date:
  • Site-wide: 62,242 out of 100,883
• Since beginning of last month:
  • Site-wide: 66,265 out of 100,883

Polygenic scores for major depressive disorder and depressive symptoms predict response to lithium in patients with bipolar disorder

• Downloaded 730 times
• Download rankings, all-time:
  • Site-wide: 21,771 out of 100,883
  • In genomics: 2,483 out of 6,254
• Year to date:
  • Site-wide: 48,158 out of 100,883
• Since beginning of last month:
  • Site-wide: 38,832 out of 100,883

Planar cell polarity pathway and development of the human visual cortex

• Downloaded 688 times
• Download rankings, all-time:
  • Site-wide: 23,883 out of 100,883
  • In neuroscience: 3,942 out of 17,976
• Year to date:
  • Site-wide: 38,966 out of 100,883
• Since beginning of last month:
  • Site-wide: 62,678 out of 100,883

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

• Downloaded 662 times
• Download rankings, all-time:
  • Site-wide: 25,222 out of 100,883
  • In genetics: 1,530 out of 5,020
• Year to date:
  • Site-wide: 62,409 out of 100,883
• Since beginning of last month:
  • Site-wide: 74,777 out of 100,883

Generative network models identify biological mechanisms of altered structural brain connectivity in schizophrenia

• Downloaded 659 times
• Download rankings, all-time:
  • Site-wide: 25,378 out of 100,883
  • In neuroscience: 4,210 out of 17,976
• Year to date:
  • Site-wide: 45,027 out of 100,883
• Since beginning of last month:
  • Site-wide: 29,922 out of 100,883

Higher genetic risk for schizophrenia is associated with living in urban and populated areas

• Downloaded 616 times
• Download rankings, all-time:
  • Site-wide: 27,832 out of 100,883
  • In genetics: 1,673 out of 5,020
• Year to date:
  • Site-wide: 65,885 out of 100,883
• Since beginning of last month:
  • Site-wide: 63,580 out of 100,883

Cross-validation of technologies for genotyping CYP2D6 and CYP2C19

• Downloaded 565 times
• Download rankings, all-time:
  • Site-wide: 31,219 out of 100,883
  • In genetics: 1,832 out of 5,020
• Year to date:
  • Site-wide: 7,685 out of 100,883
• Since beginning of last month:
  • Site-wide: 7,219 out of 100,883

New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

• Downloaded 562 times
• Download rankings, all-time:
  • Site-wide: 31,434 out of 100,883
  • In genomics: 3,164 out of 6,254
• Year to date:
  • Site-wide: 85,139 out of 100,883
• Since beginning of last month:
  • Site-wide: 93,505 out of 100,883

Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depression

• Downloaded 558 times
• Download rankings, all-time:
  • Site-wide: 31,691 out of 100,883
  • In neuroscience: 5,379 out of 17,976
• Year to date:
  • Site-wide: 55,356 out of 100,883
• Since beginning of last month:
  • Site-wide: 55,737 out of 100,883

High genetic loading for schizophrenia predicts poor response to lithium in patients with bipolar disorder: A polygenic score and cross-trait genetic analysis

• Downloaded 523 times
• Download rankings, all-time:
  • Site-wide: 34,420 out of 100,883
  • In genetics: 1,999 out of 5,020
• Year to date:
  • Site-wide: 80,344 out of 100,883
• Since beginning of last month:
  • Site-wide: 78,686 out of 100,883

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

• Downloaded 519 times
• Download rankings, all-time:
  • Site-wide: 34,765 out of 100,883
  • In genetics: 2,022 out of 5,020
• Year to date:
  • Site-wide: 23,217 out of 100,883
• Since beginning of last month:
  • Site-wide: 38,594 out of 100,883

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

• Downloaded 501 times
• Download rankings, all-time:
  • Site-wide: 36,352 out of 100,883
  • In genetics: 2,109 out of 5,020
• Year to date:
  • Site-wide: 7,522 out of 100,883
• Since beginning of last month:
  • Site-wide: 2,585 out of 100,883

Expanding the Genetic Architecture of Nicotine Dependence and its Shared Genetics with Multiple Traits: Findings from the Nicotine Dependence GenOmics (iNDiGO) Consortium

• Downloaded 487 times
• Download rankings, all-time:
  • Site-wide: 37,637 out of 100,883
  • In genomics: 3,584 out of 6,254
• Year to date:
  • Site-wide: 7,868 out of 100,883
• Since beginning of last month:
  • Site-wide: 6,733 out of 100,883

Genotype-phenotype association mining in bipolar disorder: market research meets complex genetics

• Downloaded 475 times
• Download rankings, all-time:
  • Site-wide: 38,838 out of 100,883
  • In genomics: 3,658 out of 6,254
• Year to date:
  • Site-wide: 92,637 out of 100,883
• Since beginning of last month:
  • Site-wide: 96,372 out of 100,883

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

• Downloaded 473 times
• Download rankings, all-time:
  • Site-wide: 38,971 out of 100,883
  • In genetics: 2,238 out of 5,020
• Year to date:
  • Site-wide: 35,922 out of 100,883
• Since beginning of last month:
  • Site-wide: 18,450 out of 100,883

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

• Downloaded 462 times
• Download rankings, all-time:
  • Site-wide: 40,052 out of 100,883
  • In genetics: 2,296 out of 5,020
• Year to date:
  • Site-wide: 82,451 out of 100,883
• Since beginning of last month:
  • Site-wide: 74,491 out of 100,883

Longitudinal transcriptome-wide gene expression analysis of sleep deprivation treatment shows involvement of circadian genes and immune pathways

• Downloaded 389 times
• Download rankings, all-time:
  • Site-wide: 48,351 out of 100,883
  • In epidemiology: 691 out of 1,556
• Year to date:
  • Site-wide: 57,757 out of 100,883
• Since beginning of last month:
  • Site-wide: 61,712 out of 100,883

Response to Therapeutic Sleep Deprivation: A Naturalistic Study of Clinical and Genetic Factors and Post-Treatment Depressive Symptom Trajectory

• Downloaded 316 times
• Download rankings, all-time:
  • Site-wide: 58,528 out of 100,883
  • In epidemiology: 899 out of 1,556
• Year to date:
  • Site-wide: 75,252 out of 100,883
• Since beginning of last month:
  • Site-wide: 78,066 out of 100,883

"The Heidelberg Five" Personality Dimensions: Genome-wide Associations, Polygenic Risk for Neuroticism, and Psychopathology 20 Years after Assessment

• Downloaded 144 times
• Download rankings, all-time:
  • Site-wide: 87,668 out of 100,883
  • In genomics: 5,784 out of 6,254
• Year to date:
  • Site-wide: 43,529 out of 100,883
• Since beginning of last month:
  • Site-wide: 56,367 out of 100,883