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Author: Wolfgang Huber

Rankings

  • All-time downloads: 64,526 (rank: 519 out of 364,020)
  • Categories:
    • bioengineering: 1,594 (rank: 980 (tie) out of 10,154)
    • bioinformatics: 42,220 (rank: 59 out of 31,506)
    • cancer biology: 2,976 (rank: 897 out of 24,739)
    • cell biology: 1,348 (rank: 2,858 out of 26,721)
    • genomics: 11,380 (rank: 1,128 out of 39,234)
    • molecular biology: 2,741 (rank: 768 out of 18,619)
    • systems biology: 2,267 (rank: 1,117 (tie) out of 10,830)

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Preprints

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

bioinformatics more details view paper
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    • Site-wide: 1,288 out of 84,588

HTSeq - A Python framework to work with high-throughput sequencing data

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    • In bioinformatics: 39 out of 8,113
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Multi-Omics factor analysis - a framework for unsupervised integration of multi-omic data sets

bioinformatics more details view paper
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Two independent modes of chromosome organization are revealed by cohesin removal

genomics more details view paper
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    • In genomics: 231 out of 5,461
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Orchestrating Single-Cell Analysis with Bioconductor

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    • In genomics: 335 out of 5,461
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    • Site-wide: 4,075 out of 84,588

Data-driven hypothesis weighting increases detection power in multiple testing

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    • In bioinformatics: 461 out of 8,113
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A user’s guide to the online resources for data exploration, visualization, and discovery for the Pan-Cancer Analysis of Whole Genomes project (PCAWG)

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    • In bioinformatics: 614 out of 8,113
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Condensin II inactivation in interphase does not affect chromatin folding or gene expression

genomics more details view paper
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    • In genomics: 614 out of 5,461
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SomaticSignatures: Inferring Mutational Signatures from Single Nucleotide Variants

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    • In bioinformatics: 706 out of 8,113
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    • Site-wide: 69,315 out of 84,588

Mutated SF3B1 is associated with transcript isoform changes of the genes UQCC and RPL31 both in CLLs and uveal melanomas

cancer biology more details view paper
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    • In cancer biology: 97 out of 2,962
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    • Site-wide: 59,884 out of 84,588

Transcript Isoform Differences Across Human Tissues Are Predominantly Driven By Alternative Start And Termination Sites Of Transcription

genomics more details view paper
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    • Site-wide: 4,581 out of 84,588
    • In genomics: 784 out of 5,461
  • Year to date:
    • Site-wide: 17,342 out of 84,588
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    • Site-wide: 17,246 out of 84,588

Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation

systems biology more details view paper
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    • In systems biology: 118 out of 2,232
  • Year to date:
    • Site-wide: 2,075 out of 84,588
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    • Site-wide: 4,118 out of 84,588

Biological Plasticity Rescues Target Activity in CRISPR Knockouts

bioengineering more details view paper
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    • In bioengineering: 93 out of 1,856
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    • Site-wide: 7,008 out of 84,588
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    • Site-wide: 8,500 out of 84,588

The small non-coding vault RNA1-1 acts as a riboregulator of autophagy

molecular biology more details view paper
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    • Site-wide: 5,616 out of 84,588
    • In molecular biology: 186 out of 2,843
  • Year to date:
    • Site-wide: 24,908 out of 84,588
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    • Site-wide: 28,267 out of 84,588

Non-parametric analysis of thermal proteome profiles reveals novel drug-binding proteins

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    • Site-wide: 6,171 out of 84,588
    • In bioinformatics: 1,104 out of 8,113
  • Year to date:
    • Site-wide: 11,228 out of 84,588
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    • Site-wide: 29,589 out of 84,588

FourCSeq: Analysis of 4C sequencing data

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    • In bioinformatics: 1,113 out of 8,113
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    • Site-wide: 81,745 out of 84,588

Neural lineage induction reveals multi-scale dynamics of 3D chromatin organization

molecular biology more details view paper
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    • In molecular biology: 250 out of 2,843
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    • Site-wide: 78,073 out of 84,588

Modelling asymmetric count ratios in CRISPR screens to decrease experiment size and improve phenotype detection

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    • Site-wide: 10,644 out of 84,588
    • In bioinformatics: 1,756 out of 8,113
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    • Site-wide: 15,741 out of 84,588
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    • Site-wide: 24,615 out of 84,588

A combinatorial extracellular code tunes the intracellular signaling network activity to distinct cellular responses

cell biology more details view paper
  • Downloaded 681 times
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    • In cell biology: 829 out of 4,291
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    • Site-wide: 24,679 out of 84,588
  • Since beginning of last month:
    • Site-wide: 32,112 out of 84,588

Proteome thermal stability reflects organ physiology and identifies drug-target engagement in vivo

cell biology more details view paper
  • Downloaded 667 times
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    • Site-wide: 19,985 out of 84,588
    • In cell biology: 865 out of 4,291
  • Year to date:
    • Site-wide: 14,424 out of 84,588
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    • Site-wide: 12,670 out of 84,588

Dissecting intratumor heterogeneity of nodal B cell lymphomas on the transcriptional, genetic, and drug response level

cancer biology more details view paper
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    • In cancer biology: 677 out of 2,962
  • Year to date:
    • Site-wide: 3,792 out of 84,588
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    • Site-wide: 3,688 out of 84,588

Developmental gene expression differences between humans and mammalian models

genomics more details view paper
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    • In genomics: 2,495 out of 5,461
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    • Site-wide: 17,271 out of 84,588

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

systems biology more details view paper
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    • In systems biology: 650 out of 2,232
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    • Site-wide: 37,064 out of 84,588

MDM4 is an essential disease driver targeted by 1q gain in Burkitt lymphoma

cancer biology more details view paper
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    • In cancer biology: 856 out of 2,962
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    • Site-wide: 37,764 out of 84,588

Computational analysis of ligand dose range thermal proteome profiles

bioinformatics more details view paper
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    • In bioinformatics: 6,883 out of 8,113
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