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Author: Jens Nielsen

Rankings

  • All-time downloads: 89,967 (rank: 2,402 )
  • Categories:
    • biochemistry: 515 (rank: 15,850 (tie) )
    • bioengineering: 1,919 (rank: 2,257 (tie) )
    • bioinformatics: 5,459 (rank: 2,798 (tie) )
    • cancer biology: 1,444 (rank: 7,490 (tie) )
    • ecology: 131 (rank: 25,858 (tie) )
    • endocrinology: 803 (rank: 361 (tie) )
    • epidemiology: 32,391 (rank: 747 (tie) )
    • infectious diseases: 4,942 (rank: 12,094 (tie) )
    • microbiology: 606 (rank: 32,713 (tie) )
    • molecular biology: 3,539 (rank: 1,462 (tie) )
    • pharmacology and therapeutics: 543 (rank: 793 (tie) )
    • physiology: 603 (rank: 3,642 (tie) )
    • public and global health: 11,511 (rank: 583 (tie) )
    • synthetic biology: 1,069 (rank: 2,685 (tie) )
    • systems biology: 18,381 (rank: 166 )

Downloads per author, site-wide

Preprints

Fine-tuning of coumaric acid synthesis to increase naringenin production in yeast

synthetic biology more details view paper

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Vaccine effectiveness after 1st and 2nd dose of the BNT162b2 mRNA Covid-19 Vaccine in long-term care facility residents and healthcare workers - a Danish cohort study

epidemiology more details view paper
  • Downloaded 30,863 times
  • Download rankings, all-time:
    • Site-wide: 324
    • In epidemiology: 66
  • Year to date:
    • Site-wide: 304
  • Since beginning of last month:
    • Site-wide: 932

Vaccine effectiveness of the BNT162b2 mRNA COVID-19 vaccine against RT-PCR confirmed SARS-CoV-2 infections, hospitalisations and mortality in prioritised risk groups

public and global health more details view paper
  • Downloaded 11,741 times
  • Download rankings, all-time:
    • Site-wide: 1,044
    • In public and global health: 42
  • Year to date:
    • Site-wide: 5,394
  • Since beginning of last month:
    • Site-wide: 12,366

Combined metabolic cofactor supplementation accelerates recovery in mild-to-moderate COVID-19

infectious diseases more details view paper
  • Downloaded 5,229 times
  • Download rankings, all-time:
    • Site-wide: 2,990
    • In infectious diseases: 756
  • Year to date:
    • Site-wide: 4,410
  • Since beginning of last month:
    • Site-wide: 4,997

The human secretome – the proteins secreted from human cells

molecular biology more details view paper
  • Downloaded 3,755 times
  • Download rankings, all-time:
    • Site-wide: 4,710
    • In molecular biology: 99
  • Year to date:
    • Site-wide: 10,868
  • Since beginning of last month:
    • Site-wide: 9,769

Vaccine effectiveness when combining the ChAdOx1 vaccine as the first dose with an mRNA COVID-19 vaccine as the second dose

epidemiology more details view paper
  • Downloaded 3,056 times
  • Download rankings, all-time:
    • Site-wide: 6,362
    • In epidemiology: 576
  • Year to date:
    • Site-wide: 7,900
  • Since beginning of last month:
    • Site-wide: 20,667

Evolution from adherent to suspension – systems biology of HEK293 cell line development

systems biology more details view paper
  • Downloaded 2,946 times
  • Download rankings, all-time:
    • Site-wide: 6,694
    • In systems biology: 99
  • Year to date:
    • Site-wide: 18,874
  • Since beginning of last month:
    • Site-wide: 11,979

Memote: A community-driven effort towards a standardized genome-scale metabolic model test suite

systems biology more details view paper
  • Downloaded 2,424 times
  • Download rankings, all-time:
    • Site-wide: 8,900
    • In systems biology: 132
  • Year to date:
    • Site-wide: 44,722
  • Since beginning of last month:
    • Site-wide: 40,783

Predictive engineering and optimization of tryptophan metabolism in yeast through a combination of mechanistic and machine learning models

bioengineering more details view paper
  • Downloaded 1,971 times
  • Download rankings, all-time:
    • Site-wide: 12,132
    • In bioengineering: 190
  • Year to date:
    • Site-wide: 69,361
  • Since beginning of last month:
    • Site-wide: 44,641

Machine learning applied to predicting microorganism growth temperatures and enzyme catalytic optima

bioinformatics more details view paper
  • Downloaded 1,703 times
  • Download rankings, all-time:
    • Site-wide: 15,049
    • In bioinformatics: 1,610
  • Year to date:
    • Site-wide: 36,410
  • Since beginning of last month:
    • Site-wide: 58,602

Deep learning based kcat prediction enables improved enzyme constrained model reconstruction

systems biology more details view paper
  • Downloaded 1,448 times
  • Download rankings, all-time:
    • Site-wide: 19,299
    • In systems biology: 599
  • Year to date:
    • Site-wide: 3,072
  • Since beginning of last month:
    • Site-wide: 2,037

iNetModels 2.0: an interactive visualization and database of multi-omics data

bioinformatics more details view paper
  • Downloaded 1,443 times
  • Download rankings, all-time:
    • Site-wide: 19,425
    • In bioinformatics: 2,105
  • Year to date:
    • Site-wide: 63,387
  • Since beginning of last month:
    • Site-wide: 25,587

Whole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies

systems biology more details view paper
  • Downloaded 1,367 times
  • Download rankings, all-time:
    • Site-wide: 21,098
    • In systems biology: 365
  • Year to date:
    • Site-wide: 22,305
  • Since beginning of last month:
    • Site-wide: 36,709

Genome-scale model of Rhodotorula toruloides metabolism

systems biology more details view paper
  • Downloaded 1,336 times
  • Download rankings, all-time:
    • Site-wide: 21,878
    • In systems biology: 424
  • Year to date:
    • Site-wide: 28,813
  • Since beginning of last month:
    • Site-wide: 23,787

Pan-cancer analysis of the metabolic reaction network

cancer biology more details view paper
  • Downloaded 1,323 times
  • Download rankings, all-time:
    • Site-wide: 22,224
    • In cancer biology: 473
  • Year to date:
    • Site-wide: 138,524
  • Since beginning of last month:
    • Site-wide: 147,366

Benchmarking accuracy and precision of intensity-based absolute quantification of protein abundances in Saccharomyces cerevisiae

bioinformatics more details view paper
  • Downloaded 1,313 times
  • Download rankings, all-time:
    • Site-wide: 22,463
    • In bioinformatics: 2,695
  • Year to date:
    • Site-wide: 27,349
  • Since beginning of last month:
    • Site-wide: 9,237

RAVEN 2.0: a versatile toolbox for metabolic network reconstruction and a case study on Streptomyces coelicolor

systems biology more details view paper
  • Downloaded 1,260 times
  • Download rankings, all-time:
    • Site-wide: 23,977
    • In systems biology: 421
  • Year to date:
    • Site-wide: 94,217
  • Since beginning of last month:
    • Site-wide: 67,644

Supervised generative design of regulatory DNA forgene expression control

synthetic biology more details view paper
  • Downloaded 1,203 times
  • Download rankings, all-time:
    • Site-wide: 25,767
    • In synthetic biology: 360
  • Year to date:
    • Site-wide: 19,636
  • Since beginning of last month:
    • Site-wide: 14,292

Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0

systems biology more details view paper
  • Downloaded 1,096 times
  • Download rankings, all-time:
    • Site-wide: 29,640
    • In systems biology: 843
  • Year to date:
    • Site-wide: 8,037
  • Since beginning of last month:
    • Site-wide: 3,558

The Reactobiome Unravels a New Paradigm in Human Gut Microbiome Metabolism

systems biology more details view paper
  • Downloaded 924 times
  • Download rankings, all-time:
    • Site-wide: 38,307
    • In systems biology: 851
  • Year to date:
    • Site-wide: 22,625
  • Since beginning of last month:
    • Site-wide: 23,657

Addressing the pooled amplification paradox with unique molecular identifiers in single-cell RNA-seq

bioinformatics more details view paper
  • Downloaded 809 times
  • Download rankings, all-time:
    • Site-wide: 46,517
    • In bioinformatics: 4,521
  • Year to date:
    • Site-wide: 145,504
  • Since beginning of last month:
    • Site-wide: 89,617

Stress-Induced Expression is Enriched for Evolutionarily Young Genes in Diverse Budding Yeasts

systems biology more details view paper
  • Downloaded 694 times
  • Download rankings, all-time:
    • Site-wide: 57,952
    • In systems biology: 1,124
  • Year to date:
    • Site-wide: 149,632
  • Since beginning of last month:
    • Site-wide: 149,242

Deciphering the tissue specificity of the protein secretory pathway in humans

systems biology more details view paper
  • Downloaded 675 times
  • Download rankings, all-time:
    • Site-wide: 60,280
    • In systems biology: 1,147
  • Year to date:
    • Site-wide: 183,490
  • Since beginning of last month:
    • Site-wide: 185,472

Discovery of functional alternatively spliced PKM transcripts in human cancers

systems biology more details view paper
  • Downloaded 666 times
  • Download rankings, all-time:
    • Site-wide: 61,396
    • In systems biology: 1,187
  • Year to date:
    • Site-wide: 170,167
  • Since beginning of last month:
    • Site-wide: 178,579

Proteome analysis of xylose metabolism in Rhodotorula toruloides during lipid production

microbiology more details view paper
  • Downloaded 645 times
  • Download rankings, all-time:
    • Site-wide: 64,021
    • In microbiology: 3,856
  • Year to date:
    • Site-wide: 94,380
  • Since beginning of last month:
    • Site-wide: 79,745

Fundamental Constraints In Synchronous Muscle Limit Superfast Motor Control In Vertebrates

physiology more details view paper
  • Downloaded 617 times
  • Download rankings, all-time:
    • Site-wide: 67,813
    • In physiology: 359
  • Year to date:
    • Site-wide: 137,939
  • Since beginning of last month:
    • Site-wide: 165,734

SLIMEr: probing flexibility of lipid metabolism in yeast with an improved constraint-based modeling framework

systems biology more details view paper
  • Downloaded 600 times
  • Download rankings, all-time:
    • Site-wide: 70,307
    • In systems biology: 1,395
  • Year to date:
    • Site-wide: 156,232
  • Since beginning of last month:
    • Site-wide: 150,148

Multi-omics analysis reveals the impact of microbiota on host metabolism in hepatic steatosis

endocrinology more details view paper
  • Downloaded 572 times
  • Download rankings, all-time:
    • Site-wide: 74,711
    • In endocrinology: 73
  • Year to date:
    • Site-wide: 22,610
  • Since beginning of last month:
    • Site-wide: 27,243

Informing Pharmacokinetic Models with Physiological Data: Oral Population Modeling of L-Serine in Humans

pharmacology and therapeutics more details view paper
  • Downloaded 563 times
  • Download rankings, all-time:
    • Site-wide: 76,106
    • In pharmacology and therapeutics: 88
  • Year to date:
    • Site-wide: 115,724
  • Since beginning of last month:
    • Site-wide: 180,062

Proteome constraints reveal targets for improving microbial fitness in nutrient-rich environments

systems biology more details view paper
  • Downloaded 557 times
  • Download rankings, all-time:
    • Site-wide: 77,120
    • In systems biology: 1,545
  • Year to date:
    • Site-wide: 160,913
  • Since beginning of last month:
    • Site-wide: 137,858

RMetD2: a tool for integration of relative transcriptomics data into Genome-scale metabolic models

bioinformatics more details view paper
  • Downloaded 552 times
  • Download rankings, all-time:
    • Site-wide: 77,914
    • In bioinformatics: 7,135
  • Year to date:
    • Site-wide: 82,027
  • Since beginning of last month:
    • Site-wide: 88,028

Reconstruction and Analysis of a Kluyveromyces marxianus Genome-scale Metabolic Model

systems biology more details view paper
  • Downloaded 521 times
  • Download rankings, all-time:
    • Site-wide: 83,581
    • In systems biology: 1,744
  • Year to date:
    • Site-wide: 128,173
  • Since beginning of last month:
    • Site-wide: 115,889

Transcriptome analysis of EPO and GFP HEK293 Cell-lines Reveal Shifts in Energy and ER Capacity Support Improved Erythropoietin Production in HEK293F Cells

systems biology more details view paper
  • Downloaded 485 times
  • Download rankings, all-time:
    • Site-wide: 90,663
    • In systems biology: 2,114
  • Year to date:
    • Site-wide: 48,383
  • Since beginning of last month:
    • Site-wide: 34,714

Saccharomyces cerevisiae displays a stable transcription start site landscape in multiple conditions

systems biology more details view paper
  • Downloaded 437 times
  • Download rankings, all-time:
    • Site-wide: 101,478
    • In systems biology: 2,031
  • Year to date:
    • Site-wide: 183,388
  • Since beginning of last month:
    • Site-wide: 161,905

Combined Metabolic Activators Reduces Liver Fat in Nonalcoholic Fatty Liver Disease Patients

endocrinology more details view paper
  • Downloaded 431 times
  • Download rankings, all-time:
    • Site-wide: 102,944
    • In endocrinology: 106
  • Year to date:
    • Site-wide: 36,687
  • Since beginning of last month:
    • Site-wide: 36,185

Vaccine effectiveness against SARS-CoV-2 reinfection during periods of Alpha (B.1.1.7), Delta (B.1.617.2) or Omicron (B.1.1.529) dominance: A Danish nationwide study

epidemiology more details view paper
  • Downloaded 427 times
  • Download rankings, all-time:
    • Site-wide: 103,843
    • In epidemiology: None
  • Year to date:
    • Site-wide: 6,321
  • Since beginning of last month:
    • Site-wide: 803

Genome scale modeling of the protein secretory pathway reveals novel targets for improved recombinant protein production in yeast

systems biology more details view paper
  • Downloaded 412 times
  • Download rankings, all-time:
    • Site-wide: 107,351
    • In systems biology: 2,591
  • Year to date:
    • Site-wide: 24,780
  • Since beginning of last month:
    • Site-wide: 16,267

Integrative functional analysis uncovers metabolic differences between Candida species

systems biology more details view paper
  • Downloaded 378 times
  • Download rankings, all-time:
    • Site-wide: 116,217
    • In systems biology: 2,489
  • Year to date:
    • Site-wide: 67,812
  • Since beginning of last month:
    • Site-wide: 53,517

A novel yeast hybrid modeling framework integrating Boolean and enzyme-constrained networks enables exploration of the interplay between signaling and metabolism

systems biology more details view paper
  • Downloaded 355 times
  • Download rankings, all-time:
    • Site-wide: 122,381
    • In systems biology: 2,450
  • Year to date:
    • Site-wide: 136,157
  • Since beginning of last month:
    • Site-wide: 128,157

Analytical Performance of a Standardized Kit for Mass Spectrometry-based Measurements of Human Glycosaminoglycans

biochemistry more details view paper
  • Downloaded 349 times
  • Download rankings, all-time:
    • Site-wide: 124,011
    • In biochemistry: 3,879
  • Year to date:
    • Site-wide: 65,084
  • Since beginning of last month:
    • Site-wide: 21,738

Integrated metabolic modeling, culturing and transcriptomics explains enhanced virulence of V. cholerae during co-infection with ETEC

systems biology more details view paper
  • Downloaded 281 times
  • Download rankings, all-time:
    • Site-wide: 143,928
    • In systems biology: 2,880
  • Year to date:
    • Site-wide: 123,234
  • Since beginning of last month:
    • Site-wide: 68,365

Quantifying absolute gene expression profiles reveals distinct regulation of central carbon metabolism genes in yeast

systems biology more details view paper
  • Downloaded 275 times
  • Download rankings, all-time:
    • Site-wide: 145,906
    • In systems biology: 2,851
  • Year to date:
    • Site-wide: 165,484
  • Since beginning of last month:
    • Site-wide: 182,754

A Single Chromosome Strain of S. cerevisiae Exhibits Diminished Ethanol Metabolism and Tolerance.

systems biology more details view paper
  • Downloaded 263 times
  • Download rankings, all-time:
    • Site-wide: 149,399
    • In systems biology: 2,905
  • Year to date:
    • Site-wide: 162,600
  • Since beginning of last month:
    • Site-wide: 181,514

A network-based approach reveals the dysregulated transcriptional regulation in non-alcohol fatty liver disease

systems biology more details view paper
  • Downloaded 256 times
  • Download rankings, all-time:
    • Site-wide: 151,435
    • In systems biology: 3,016
  • Year to date:
    • Site-wide: 90,579
  • Since beginning of last month:
    • Site-wide: 93,018

Analysis of Normal Levels of Urine and Plasma Free Glycosaminoglycans in Adults

biochemistry more details view paper
  • Downloaded 254 times
  • Download rankings, all-time:
    • Site-wide: 152,097
    • In biochemistry: 4,422
  • Year to date:
    • Site-wide: 111,430
  • Since beginning of last month:
    • Site-wide: 102,489

Generation and analysis of context-specific genome-scale metabolic models derived from single-cell RNA-Seq data

systems biology more details view paper
  • Downloaded 232 times
  • Download rankings, all-time:
    • Site-wide: 158,455
    • In systems biology: None
  • Year to date:
    • Site-wide: 15,950
  • Since beginning of last month:
    • Site-wide: 5,037

Learning deep representations of enzyme thermal adaptation

bioinformatics more details view paper
  • Downloaded 232 times
  • Download rankings, all-time:
    • Site-wide: 158,433
    • In bioinformatics: None
  • Year to date:
    • Site-wide: 15,957
  • Since beginning of last month:
    • Site-wide: 18,132

Cellular limitation of enzymatic capacity explains glutamine addiction in cancers

cancer biology more details view paper
  • Downloaded 206 times
  • Download rankings, all-time:
    • Site-wide: 165,163
    • In cancer biology: 5,167
  • Year to date:
    • Site-wide: 18,940
  • Since beginning of last month:
    • Site-wide: 60,138

Non-random organization of flux control mechanisms in yeast central metabolic pathways

systems biology more details view paper
  • Downloaded 204 times
  • Download rankings, all-time:
    • Site-wide: 165,904
    • In systems biology: 3,280
  • Year to date:
    • Site-wide: 45,792
  • Since beginning of last month:
    • Site-wide: 102,468

Machine learning-based investigation of the cancer protein secretory pathway

systems biology more details view paper
  • Downloaded 175 times
  • Download rankings, all-time:
    • Site-wide: 172,977
    • In systems biology: 3,294
  • Year to date:
    • Site-wide: 171,855
  • Since beginning of last month:
    • Site-wide: 129,497

Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning

systems biology more details view paper
  • Downloaded 173 times
  • Download rankings, all-time:
    • Site-wide: 173,254
    • In systems biology: 3,502
  • Year to date:
    • Site-wide: 24,112
  • Since beginning of last month:
    • Site-wide: 53,150

Amino acid and nucleotide metabolism shape the selection of trophic levels in animals

ecology more details view paper
  • Downloaded 158 times
  • Download rankings, all-time:
    • Site-wide: 176,676
    • In ecology: 5,969
  • Year to date:
    • Site-wide: 108,357
  • Since beginning of last month:
    • Site-wide: 82,896

Systems analysis of metabolic responses to a mixed meal test in an obese cohort reveals links between tissue metabolism and the gut microbiota

systems biology more details view paper
  • Downloaded 112 times
  • Download rankings, all-time:
    • Site-wide: 184,312
    • In systems biology: None
  • Year to date:
    • Site-wide: 41,429
  • Since beginning of last month:
    • Site-wide: 20,533

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