Author: Andrew J Saykin

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Preprints

The genetic architecture of the human cerebral cortex

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  • Site-wide: 1,015
  • In genetics: 30
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  • Site-wide: 17,751
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  • Site-wide: None

Greater male than female variability in regional brain structure across the lifespan

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  • Site-wide: 3,006
  • In neuroscience: 231
• Year to date:
  • Site-wide: 11,189
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  • Site-wide: 10,619

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

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  • Site-wide: 8,948
  • In genetics: 444
• Year to date:
  • Site-wide: 103,221
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  • Site-wide: None

The Alzheimer’s Disease Metabolome: Effects of Sex and APOE ε4 genotype

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  • Site-wide: 11,292
  • In bioinformatics: 1,400
• Year to date:
  • Site-wide: 31,368
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  • Site-wide: 34,130

Altered Bile Acid Profile Associates with Cognitive Impairment in Alzheimer's Disease: An Emerging Role for Gut Microbiome

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  • Site-wide: 11,332
  • In neuroscience: 1,286
• Year to date:
  • Site-wide: 40,937
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  • Site-wide: 50,535

Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years

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  • Site-wide: 19,893
  • In neuroscience: 2,548
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  • Site-wide: 13,064
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  • Site-wide: 7,826

Serum triglycerides in Alzheimer’s disease: Relation to neuroimaging and CSF biomarkers

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  • Site-wide: 22,371
  • In neuroscience: 2,938
• Year to date:
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  • Site-wide: 53,242

Do Candidate Genes Affect the Brain's White Matter Microstructure? Large-Scale Evaluation of 6,165 Diffusion MRI Scans

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  • Site-wide: 25,953
  • In neuroscience: 3,494
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  • Site-wide: 97,127

Heritability of regional brain volumes in large-scale neuroimaging and genetic studies

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  • Site-wide: 26,574
  • In genetics: 1,323
• Year to date:
  • Site-wide: 69,967
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  • Site-wide: 72,874

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

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  • Site-wide: 26,612
  • In genomics: 2,518
• Year to date:
  • Site-wide: 55,434
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  • Site-wide: 37,960

Planar cell polarity pathway and development of the human visual cortex

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  • Site-wide: 29,225
  • In neuroscience: 4,007
• Year to date:
  • Site-wide: 45,584
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  • Site-wide: 62,664

Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years

• Downloaded 710 times
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  • Site-wide: 31,981
  • In neuroscience: 4,459
• Year to date:
  • Site-wide: 19,970
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  • Site-wide: 15,280

Altered Bile Acid Profile in Mild Cognitive Impairment and Alzheimer's Disease: Relationship to Neuroimaging and CSF Biomarkers

• Downloaded 703 times
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  • Site-wide: 32,419
  • In neuroscience: 4,521
• Year to date:
  • Site-wide: 34,871
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  • Site-wide: 24,242

Identifying differences in bile acid pathways for cholesterol clearance in Alzheimer’s disease using metabolic networks of human brain regions

• Downloaded 686 times
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  • Site-wide: 33,554
  • In systems biology: 769
• Year to date:
  • Site-wide: 22,186
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  • Site-wide: 17,209

Task-Evoked Functional Connectivity Does Not Explain Functional Connectivity Differences Between Rest and Task Conditions

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  • Site-wide: 34,343
  • In neuroscience: 4,832
• Year to date:
  • Site-wide: 55,714
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  • Site-wide: 97,501

Genetic Variants and Functional Pathways Associated with Resilience to Alzheimer's Disease

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  • Site-wide: 34,581
  • In genetics: 1,694
• Year to date:
  • Site-wide: 57,990
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  • Site-wide: 83,810

Genetic data and cognitively-defined late-onset Alzheimer's disease subgroups

• Downloaded 587 times
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  • Site-wide: 40,995
  • In genetics: 1,973
• Year to date:
  • Site-wide: 109,657
• Since beginning of last month:
  • Site-wide: 78,540

A/T/N polygenic risk score for cognitive decline in old age

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  • Site-wide: 52,712
  • In genomics: 4,094
• Year to date:
  • Site-wide: 53,762
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  • Site-wide: 50,074

Sets of Co-regulated Serum Lipids are Associated with Alzheimer Disease Pathophysiology

• Downloaded 428 times
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  • Site-wide: 58,928
  • In neuroscience: 8,958
• Year to date:
  • Site-wide: 88,515
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  • Site-wide: 62,507

Combining two large clinical cohorts (AIBL and ADNI) to identify multiple lipid metabolic pathways in prevalent and incident Alzheimer's disease.

• Downloaded 358 times
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  • Site-wide: 69,948
  • In neurology: 143
• Year to date:
  • Site-wide: 26,220
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  • Site-wide: 58,005

Identification of functionally connected multi-omic biomarkers for Alzheimer's Disease using modularity-constrained Lasso

• Downloaded 290 times
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  • Site-wide: 82,789
  • In bioinformatics: 7,505
• Year to date:
  • Site-wide: 97,610
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  • Site-wide: 77,702

Functional biological paths altered in Alzheimer's disease: from genes to bile acids

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  • Site-wide: 94,997
  • In bioinformatics: 8,286
• Year to date:
  • Site-wide: 78,564
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  • Site-wide: 104,049

WEVar: a novel statistical learning framework for predicting noncoding regulatory variants

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  • Site-wide: 107,241
  • In bioinformatics: 9,024
• Year to date:
  • Site-wide: 31,578
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  • Site-wide: 25,536

Differential brain atrophy and neurogenetic profiles in cognitively-defined Alzheimer's disease subgroups

• Downloaded 139 times
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  • Site-wide: 114,371
  • In neuroscience: 17,765
• Year to date:
  • Site-wide: 104,038
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  • Site-wide: 87,923

Temporal stability of the ventral attention network and general cognition along the Alzheimer's disease spectrum

• Downloaded 128 times
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  • Site-wide: 116,294
  • In neurology: 443
• Year to date:
  • Site-wide: 58,689
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  • Site-wide: 57,232

Deep learning detection of informative features in tau PET for Alzheimer' s disease classification

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  • Site-wide: 116,939
  • In neuroscience: 18,158
• Year to date:
  • Site-wide: None
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  • Site-wide: None

Elevated plasma cortisol associated with larger ventricles and smaller hippocampal volumes, a study in 2 independent elderly cohorts

• Downloaded 114 times
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  • Site-wide: 118,940
  • In neuroscience: 18,450
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Serum Metabolites Associate with Brain Amyloid Beta Deposition, Cognitive Dysfunction, and Alzheimers Disease Progression

• Downloaded 98 times
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  • Site-wide: 121,773
  • In neuroscience: 18,864
• Year to date:
  • Site-wide: 57,017
• Since beginning of last month:
  • Site-wide: 48,253