Author: Uwe Völker

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Preprints

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

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Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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  • Site-wide: 3,953
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Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

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The Polygenic and Monogenic Basis of Blood Traits and Diseases

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  • Site-wide: 7,364
  • In genetic and genomic medicine: 24
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Cell specific eQTL analysis without sorting cells

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Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

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Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

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Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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Polygenic architecture of human neuroanatomical diversity

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  • In neuroscience: 3,328
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sPLINK: A Federated, Privacy-Preserving Tool as a Robust Alternative to Meta-Analysis in Genome-Wide Association Studies

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  • Site-wide: 26,270
  • In bioinformatics: 3,068
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Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

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  • Site-wide: 27,403
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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

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  • In genetics: 1,949
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  • Site-wide: 63,938

Tissue-specific multiOMICs analysis of atrial fibrillation

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Genetic insights into the biological mechanisms governing human ovarian ageing

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  • Site-wide: 43,335
  • In sexual and reproductive health: 18
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  • Site-wide: 2,215
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Discovering patterns of pleiotropy in genome-wide association studies

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  • Site-wide: 93,160

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

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  • Site-wide: 44,476
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  • Site-wide: 67,647
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  • Site-wide: 108,368

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

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  • Site-wide: 44,835
  • In genetics: 2,114
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  • Site-wide: 89,839
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Common variants in ABCG8 and TRAF3 genes confer risk for gallstone disease and gallbladder cancer in admixed Latinos with Mapuche Native American ancestry

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Genome wide association analysis in dilated cardiomyopathy reveals two new key players in systolic heart failure on chromosome 3p25.1 and 22q11.23

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Metabolic differences between symbiont subpopulations in the deep-sea tubeworm Riftia pachyptila

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  • In microbiology: 4,147
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Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women

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  • Site-wide: 65,266
  • In genetic and genomic medicine: 211
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  • Site-wide: 24,277

Genetic factors influencing a neurobiological substrate for psychiatric disorders

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  • Site-wide: 68,578
  • In genetics: 3,147
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Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels

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  • Site-wide: 69,412
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Pneumococcal metabolic adaptation and colonization is regulated by the two-component regulatory system 08

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  • Site-wide: 76,643
  • In microbiology: 5,271
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Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

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  • Site-wide: 90,180
  • In genetics: 4,081
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  • Site-wide: 97,280

Essentiality of c-di-AMP in Bacillus subtilis: Bypassing mutations converge in potassium and glutamate homeostasis

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  • In microbiology: 6,718
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  • Site-wide: 68,906

KCND3 is a novel susceptibility locus for early repolarization

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  • Site-wide: 95,638
  • In genetics: 4,296
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Circulating proteomic patterns in AF related left atrial remodeling indicate involvement of coagulation and complement cascade

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  • Site-wide: 97,329
  • In molecular biology: 2,909
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Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

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  • Site-wide: 104,515
  • In genomics: 6,111
• Year to date:
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  • Site-wide: 69,196

Estimating the effect of lipids on IGF axis and subsequent breast cancer risk

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