Author: Sahil Seth

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Preprints

Evaluation and Design of Genome-wide CRISPR/Cas9 Knockout Screens

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  • In systems biology: 31
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  • Site-wide: 104,896

A Comprehensive Assessment of Somatic Mutation Calling in Cancer Genomes

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  • Site-wide: 5,039
  • In genomics: 615
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  • Site-wide: 100,598
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  • Site-wide: 65,419

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma

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  • Site-wide: 6,691
  • In cancer biology: 109
• Year to date:
  • Site-wide: 77,531
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  • Site-wide: 31,109

Process-specific somatic mutation distributions vary with three-dimensional genome structure

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  • Site-wide: 10,008
  • In genomics: 1,137
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Flowr: Robust and efficient pipelines using a simple language-agnostic approach

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  • Site-wide: 30,674
  • In bioinformatics: 3,549
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  • Site-wide: 100,199

Inhibition of histone acetyltranserase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a novel gain of function

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  • Site-wide: 52,924
  • In cancer biology: 1,482
• Year to date:
  • Site-wide: 5,550
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Diversity Across the Pancreatic Ductal Adenocarcinoma Disease Spectrum Revealed by Network-Anchored Functional Genomics

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  • Site-wide: 78,041
  • In cancer biology: 2,313
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  • Site-wide: 40,838
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Medium-chain acyl-CoA dehydrogenase, a gatekeeper of mitochondrial function in glioblastoma multiforme

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  • Site-wide: 103,437
  • In cancer biology: 3,179
• Year to date:
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