Author: Sahil Seth

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Preprints

Evaluation and Design of Genome-wide CRISPR/Cas9 Knockout Screens

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A Comprehensive Assessment of Somatic Mutation Calling in Cancer Genomes

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  • In genomics: 647
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Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma

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  • Site-wide: 7,418
  • In cancer biology: 122
• Year to date:
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Process-specific somatic mutation distributions vary with three-dimensional genome structure

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  • In genomics: 1,219
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Flowr: Robust and efficient pipelines using a simple language-agnostic approach

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  • Site-wide: 33,816
  • In bioinformatics: 3,775
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Inhibition of histone acetyltranserase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a novel gain of function

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  • Site-wide: 42,641
  • In cancer biology: 1,178
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Diversity Across the Pancreatic Ductal Adenocarcinoma Disease Spectrum Revealed by Network-Anchored Functional Genomics

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  • In cancer biology: 2,307
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Medium-chain acyl-CoA dehydrogenase, a gatekeeper of mitochondrial function in glioblastoma multiforme

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  • In cancer biology: 3,254
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