Author: Young Hwan Chang

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Preprints

An Integrated Clinical, Omic, and Image Atlas of an Evolving Metastatic Breast Cancer

• Downloaded 1,375 times
• Download rankings, all-time:
  • Site-wide: 24,253
  • In cancer biology: 589
• Year to date:
  • Site-wide: 128,314
• Since beginning of last month:
  • Site-wide: 56,397

ME-VAE: Multi-Encoder Variational AutoEncoder for Controlling Multiple Transformational Features in Single Cell Image Analysis

• Downloaded 1,222 times
• Download rankings, all-time:
  • Site-wide: 29,214
  • In bioinformatics: 3,145
• Year to date:
  • Site-wide: 27,483
• Since beginning of last month:
  • Site-wide: 23,885

Exact Reconstruction of Gene Regulatory Networks using Compressive Sensing

• Downloaded 1,136 times
• Download rankings, all-time:
  • Site-wide: 32,799
  • In systems biology: 592
• Year to date:
  • Site-wide: 192,968
• Since beginning of last month:
  • Site-wide: 181,156

Disentangling Multidimensional Spatio-Temporal Data into their Common and Aberrant Responses

• Downloaded 1,050 times
• Download rankings, all-time:
  • Site-wide: 36,967
  • In systems biology: 688
• Year to date:
  • Site-wide: 64,530
• Since beginning of last month:
  • Site-wide: 209,770

Network Identification Methods

• Downloaded 987 times
• Download rankings, all-time:
  • Site-wide: 40,751
  • In systems biology: 763
• Year to date:
  • Site-wide: 94,729
• Since beginning of last month:
  • Site-wide: 196,467

SHIFT: speedy histological-to-immunofluorescent translation of whole slide images enabled by deep learning

• Downloaded 977 times
• Download rankings, all-time:
  • Site-wide: 41,370
  • In systems biology: 782
• Year to date:
  • Site-wide: 142,699
• Since beginning of last month:
  • Site-wide: 202,809

High-throughput single-particle tracking reveals nested membrane nanodomain organization that dictates Ras diffusion and trafficking

• Downloaded 923 times
• Download rankings, all-time:
  • Site-wide: 45,127
  • In biophysics: 1,403
• Year to date:
  • Site-wide: 53,080
• Since beginning of last month:
  • Site-wide: 200,238

Reconstruction of Gene Regulatory Networks based on Repairing Sparse Low-rank Matrices

• Downloaded 887 times
• Download rankings, all-time:
  • Site-wide: 48,074
  • In systems biology: 934
• Year to date:
  • Site-wide: 94,173
• Since beginning of last month:
  • Site-wide: 196,554

RESTORE: Robust intEnSiTy nORmalization mEthod for Multiplexed Imaging

• Downloaded 817 times
• Download rankings, all-time:
  • Site-wide: 54,374
  • In systems biology: 1,084
• Year to date:
  • Site-wide: 62,659
• Since beginning of last month:
  • Site-wide: 104,459

T cell Egress via Lymphatic Vessels Limits the Intratumoral T cell Repertoire in Melanoma

• Downloaded 762 times
• Download rankings, all-time:
  • Site-wide: 60,359
  • In immunology: 2,149
• Year to date:
  • Site-wide: 5,686
• Since beginning of last month:
  • Site-wide: 16,886

Multi-omics analysis of serial samples from metastatic TNBC patients on PARP inhibitor monotherapy provide insight into rational PARP inhibitor therapy combinations

• Downloaded 727 times
• Download rankings, all-time:
  • Site-wide: 64,632
  • In oncology: 124
• Year to date:
  • Site-wide: 122,643
• Since beginning of last month:
  • Site-wide: 125,933

HER2 Cancer Protrusion Growth Signaling Regulated by Unhindered, Localized Filopodial Dynamics

• Downloaded 703 times
• Download rankings, all-time:
  • Site-wide: 67,753
  • In cancer biology: 1,996
• Year to date:
  • Site-wide: 97,586
• Since beginning of last month:
  • Site-wide: 91,775

Toward reproducible, scalable, and robust data analysis across multiplex tissue imaging platforms

• Downloaded 633 times
• Download rankings, all-time:
  • Site-wide: 78,121
  • In systems biology: 1,581
• Year to date:
  • Site-wide: 89,921
• Since beginning of last month:
  • Site-wide: 110,188

Morphodynamical cell-state description via live-cell imaging trajectory embedding

• Downloaded 553 times
• Download rankings, all-time:
  • Site-wide: 92,780
  • In systems biology: 2,087
• Year to date:
  • Site-wide: 8,471
• Since beginning of last month:
  • Site-wide: 5,143

Quantitative multiplex immunohistochemistry reveals inter- and intra-patient lymphovascular and immune heterogeneity in primary cutaneous melanoma

• Downloaded 489 times
• Download rankings, all-time:
  • Site-wide: 106,817
  • In cancer biology: 3,222
• Year to date:
  • Site-wide: 111,380
• Since beginning of last month:
  • Site-wide: 115,128

VISTA: Virtual ImmunoSTAining for pancreatic disease quantification in murine cohorts

• Downloaded 487 times
• Download rankings, all-time:
  • Site-wide: 107,345
  • In bioinformatics: 9,186
• Year to date:
  • Site-wide: 151,657
• Since beginning of last month:
  • Site-wide: 121,767

Predicting Primary Site of Secondary Liver Cancer with a Neural Estimator of Metastatic Origin (NEMO)

• Downloaded 477 times
• Download rankings, all-time:
  • Site-wide: 109,791
  • In cancer biology: 3,332
• Year to date:
  • Site-wide: 96,275
• Since beginning of last month:
  • Site-wide: 179,491

Relevance of Circulating Hybrid Cells as a Non-Invasive Biomarker for Myriad Solid Tumors

• Downloaded 450 times
• Download rankings, all-time:
  • Site-wide: 116,283
  • In cancer biology: 3,535
• Year to date:
  • Site-wide: 177,584
• Since beginning of last month:
  • Site-wide: 61,753

A Novel Mouse Model that Recapitulates the Heterogeneity of Human Triple Negative Breast Cancer

• Downloaded 357 times
• Download rankings, all-time:
  • Site-wide: 142,822
  • In cancer biology: 4,585
• Year to date:
  • Site-wide: 18,313
• Since beginning of last month:
  • Site-wide: 19,043

Single cell tracking based on Voronoi partition via stable matching

• Downloaded 354 times
• Download rankings, all-time:
  • Site-wide: 143,648
  • In systems biology: 2,932
• Year to date:
  • Site-wide: 65,977
• Since beginning of last month:
  • Site-wide: 102,138

DISSECT: DISentangle SharablE ConTent for Multimodal Integration and Crosswise-mapping

• Downloaded 294 times
• Download rankings, all-time:
  • Site-wide: 161,874
  • In bioinformatics: 12,529
• Year to date:
  • Site-wide: 125,747
• Since beginning of last month:
  • Site-wide: 131,497

Transfer Learning for Inference of Metastatic Origin from Whole Slide Histology

• Downloaded 265 times
• Download rankings, all-time:
  • Site-wide: 170,574
  • In pathology: 979
• Year to date:
  • Site-wide: 179,066
• Since beginning of last month:
  • Site-wide: 172,175

3D multiplexed tissue imaging reconstruction and optimized region-of-interest (ROI) selection through deep learning model of channels embedding

• Downloaded 101 times
• Download rankings, all-time:
  • Site-wide: 207,352
  • In bioinformatics: None
• Year to date:
  • Site-wide: 18,984
• Since beginning of last month:
  • Site-wide: 2,911

Computational Multiplex Panel Reduction to Maximize Information Retention in Breast Cancer Tissue Microarrays

• Downloaded 88 times
• Download rankings, all-time:
  • Site-wide: 209,725
  • In bioinformatics: 15,083
• Year to date:
  • Site-wide: 101,116
• Since beginning of last month:
  • Site-wide: 58,865

Optimal drug treatment for reducing long-term drug resistance

• Downloaded 71 times
• Download rankings, all-time:
  • Site-wide: 212,840
  • In systems biology: 4,028
• Year to date:
  • Site-wide: 100,909
• Since beginning of last month:
  • Site-wide: 138,384