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Author: Aki S. Havulinna

  • ORCiD: http://orcid.org/0000-0002-4787-8959
  • Most recently observed institution: Institute for Molecular Medicine Finland FIMM, HiLIFE, University of Helsinki, Tukholmankatu 8, 00014 Helsinki, Finland. Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.

Rankings

  • All-time downloads: 44,817 (rank: 4,845 )
  • Categories:
    • bioinformatics: 2,545 (rank: 6,948 )
    • cardiovascular medicine: 399 (rank: 2,268 (tie) )
    • epidemiology: 6,154 (rank: 3,013 )
    • gastroenterology: 1,103 (rank: 407 (tie) )
    • genetic and genomic medicine: 2,447 (rank: 1,841 (tie) )
    • genetics: 13,900 (rank: 1,209 )
    • genomics: 13,840 (rank: 1,453 )
    • microbiology: 2,595 (rank: 7,229 (tie) )
    • systems biology: 1,834 (rank: 2,772 (tie) )

Downloads per author, site-wide

Preprints

Taxonomic Signatures of Long-Term Mortality Risk in Human Gut Microbiota

epidemiology more details view paper
  • Downloaded 3,809 times
  • Download rankings, all-time:
    • Site-wide: 4,119
    • In epidemiology: 421
  • Year to date:
    • Site-wide: 25,420
  • Since beginning of last month:
    • Site-wide: 28,244

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

genetics more details view paper
  • Downloaded 3,310 times
  • Download rankings, all-time:
    • Site-wide: 5,010
    • In genetics: 180
  • Year to date:
    • Site-wide: 36,431
  • Since beginning of last month:
    • Site-wide: 52,535

Polygenic and clinical risk scores and their impact on age at onset of cardiometabolic diseases and common cancers

genomics more details view paper
  • Downloaded 2,983 times
  • Download rankings, all-time:
    • Site-wide: 5,823
    • In genomics: 572
  • Year to date:
    • Site-wide: 143,571
  • Since beginning of last month:
    • Site-wide: 81,663

Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

genetics more details view paper
  • Downloaded 2,763 times
  • Download rankings, all-time:
    • Site-wide: 6,483
    • In genetics: 255
  • Year to date:
    • Site-wide: 29,185
  • Since beginning of last month:
    • Site-wide: 19,515

Bacterial modification of the host glycosaminoglycan heparan sulfate modulates SARS-CoV-2 infectivity

microbiology more details view paper
  • Downloaded 2,595 times
  • Download rankings, all-time:
    • Site-wide: 7,137
    • In microbiology: 431
  • Year to date:
    • Site-wide: 48,312
  • Since beginning of last month:
    • Site-wide: 17,137

Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

genomics more details view paper
  • Downloaded 2,103 times
  • Download rankings, all-time:
    • Site-wide: 9,652
    • In genomics: 946
  • Year to date:
    • Site-wide: 76,860
  • Since beginning of last month:
    • Site-wide: 40,913

Elevated alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality

systems biology more details view paper
  • Downloaded 1,834 times
  • Download rankings, all-time:
    • Site-wide: 11,898
    • In systems biology: 198
  • Year to date:
    • Site-wide: 57,449
  • Since beginning of last month:
    • Site-wide: 159,889

Refining fine-mapping: effect sizes and regional heritability

genetics more details view paper
  • Downloaded 1,742 times
  • Download rankings, all-time:
    • Site-wide: 12,823
    • In genetics: 534
  • Year to date:
    • Site-wide: 30,583
  • Since beginning of last month:
    • Site-wide: 23,570

Exome sequencing identifies high-impact trait-associated alleles enriched in Finns

genomics more details view paper
  • Downloaded 1,536 times
  • Download rankings, all-time:
    • Site-wide: 15,524
    • In genomics: 1,488
  • Year to date:
    • Site-wide: 105,678
  • Since beginning of last month:
    • Site-wide: 67,521

Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort

genetic and genomic medicine more details view paper
  • Downloaded 1,382 times
  • Download rankings, all-time:
    • Site-wide: 18,244
    • In genetic and genomic medicine: 88
  • Year to date:
    • Site-wide: 10,717
  • Since beginning of last month:
    • Site-wide: 7,048

OGUs enable effective, phylogeny-aware analysis of even shallow metagenome community structures

bioinformatics more details view paper
  • Downloaded 1,364 times
  • Download rankings, all-time:
    • Site-wide: 18,580
    • In bioinformatics: 2,072
  • Year to date:
    • Site-wide: 28,731
  • Since beginning of last month:
    • Site-wide: 15,795

Genetics of human plasma lipidome: Understanding lipid metabolism and its link to diseases beyond traditional lipids

genetics more details view paper
  • Downloaded 1,276 times
  • Download rankings, all-time:
    • Site-wide: 20,548
    • In genetics: 896
  • Year to date:
    • Site-wide: 45,410
  • Since beginning of last month:
    • Site-wide: 83,456

Haplotype sharing provides insights into fine-scale population history and disease in Finland

genetics more details view paper
  • Downloaded 1,201 times
  • Download rankings, all-time:
    • Site-wide: 22,569
    • In genetics: 967
  • Year to date:
    • Site-wide: 21,470
  • Since beginning of last month:
    • Site-wide: 81,083

Genomic prediction of coronary heart disease

genomics more details view paper
  • Downloaded 1,196 times
  • Download rankings, all-time:
    • Site-wide: 22,711
    • In genomics: 2,068
  • Year to date:
    • Site-wide: 147,754
  • Since beginning of last month:
    • Site-wide: 162,346

Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

epidemiology more details view paper
  • Downloaded 1,106 times
  • Download rankings, all-time:
    • Site-wide: 25,581
    • In epidemiology: 1,535
  • Year to date:
    • Site-wide: 56,975
  • Since beginning of last month:
    • Site-wide: 40,670

Geographic variation and bias in polygenic scores of complex diseases and traits in Finland

genetics more details view paper
  • Downloaded 1,082 times
  • Download rankings, all-time:
    • Site-wide: 26,453
    • In genetics: 1,143
  • Year to date:
    • Site-wide: 146,868
  • Since beginning of last month:
    • Site-wide: 81,525

Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

genomics more details view paper
  • Downloaded 1,008 times
  • Download rankings, all-time:
    • Site-wide: 29,377
    • In genomics: 2,537
  • Year to date:
    • Site-wide: 151,099
  • Since beginning of last month:
    • Site-wide: 149,605

Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma

genetics more details view paper
  • Downloaded 988 times
  • Download rankings, all-time:
    • Site-wide: 30,258
    • In genetics: 1,307
  • Year to date:
    • Site-wide: 58,848
  • Since beginning of last month:
    • Site-wide: 153,027

Gene-Gene Interaction Detection with Deep Learning

bioinformatics more details view paper
  • Downloaded 934 times
  • Download rankings, all-time:
    • Site-wide: 32,903
    • In bioinformatics: 3,552
  • Year to date:
    • Site-wide: 69,540
  • Since beginning of last month:
    • Site-wide: 29,448

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

genomics more details view paper
  • Downloaded 885 times
  • Download rankings, all-time:
    • Site-wide: 35,552
    • In genomics: 2,921
  • Year to date:
    • Site-wide: 5,052
  • Since beginning of last month:
    • Site-wide: 323

An efficient and accurate frailty model approach for genome-wide survival association analysis controlling for population structure and relatedness in large-scale biobanks

genomics more details view paper
  • Downloaded 868 times
  • Download rankings, all-time:
    • Site-wide: 36,591
    • In genomics: 2,981
  • Year to date:
    • Site-wide: 12,738
  • Since beginning of last month:
    • Site-wide: 20,078

An interaction map of circulating metabolites, immune gene networks and their genetic regulation

genomics more details view paper
  • Downloaded 831 times
  • Download rankings, all-time:
    • Site-wide: 38,980
    • In genomics: 3,141
  • Year to date:
    • Site-wide: 58,516
  • Since beginning of last month:
    • Site-wide: 161,958

Links between gut microbiome composition and fatty liver disease in a large population sample

gastroenterology more details view paper
  • Downloaded 807 times
  • Download rankings, all-time:
    • Site-wide: 40,648
    • In gastroenterology: 41
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: None

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

genomics more details view paper
  • Downloaded 805 times
  • Download rankings, all-time:
    • Site-wide: 40,803
    • In genomics: 3,245
  • Year to date:
    • Site-wide: 79,560
  • Since beginning of last month:
    • Site-wide: 100,771

Mono- and bi-allelic effects of coding variants on disease in 176,899 Finns

genetic and genomic medicine more details view paper
  • Downloaded 753 times
  • Download rankings, all-time:
    • Site-wide: 44,978
    • In genetic and genomic medicine: 223
  • Year to date:
    • Site-wide: 3,635
  • Since beginning of last month:
    • Site-wide: 4,210

Polygenic risk score of alcohol consumption predicts alcohol-related morbidity and all-cause mortality

genomics more details view paper
  • Downloaded 699 times
  • Download rankings, all-time:
    • Site-wide: 49,799
    • In genomics: 3,755
  • Year to date:
    • Site-wide: 138,507
  • Since beginning of last month:
    • Site-wide: 155,965

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

genetics more details view paper
  • Downloaded 674 times
  • Download rankings, all-time:
    • Site-wide: 52,357
    • In genetics: 2,199
  • Year to date:
    • Site-wide: 57,933
  • Since beginning of last month:
    • Site-wide: 119,212

Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

genomics more details view paper
  • Downloaded 562 times
  • Download rankings, all-time:
    • Site-wide: 66,108
    • In genomics: 4,635
  • Year to date:
    • Site-wide: 73,331
  • Since beginning of last month:
    • Site-wide: 100,156

The landscape of incident disease risk for the biomarker GlycA and its mortality stratification in angiography patients

epidemiology more details view paper
  • Downloaded 498 times
  • Download rankings, all-time:
    • Site-wide: 76,289
    • In epidemiology: 3,426
  • Year to date:
    • Site-wide: 101,575
  • Since beginning of last month:
    • Site-wide: 153,864

Association of Structural Variation with Cardiometabolic Traits in Finns

genetics more details view paper
  • Downloaded 448 times
  • Download rankings, all-time:
    • Site-wide: 85,698
    • In genetics: 3,549
  • Year to date:
    • Site-wide: 64,647
  • Since beginning of last month:
    • Site-wide: 114,533

Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health

genetics more details view paper
  • Downloaded 416 times
  • Download rankings, all-time:
    • Site-wide: 92,267
    • In genetics: 3,798
  • Year to date:
    • Site-wide: 66,534
  • Since beginning of last month:
    • Site-wide: 50,839

High Density Lipoprotein pathway as a therapeutic target for coronary heart disease: individual participant meta-analysis in 28,597 individuals with 4197 coronary events

cardiovascular medicine more details view paper
  • Downloaded 399 times
  • Download rankings, all-time:
    • Site-wide: 96,107
    • In cardiovascular medicine: 215
  • Year to date:
    • Site-wide: 26,167
  • Since beginning of last month:
    • Site-wide: 91,024

Genetic variation in apolipoprotein A-I concentrations and risk of coronary artery disease

epidemiology more details view paper
  • Downloaded 375 times
  • Download rankings, all-time:
    • Site-wide: 101,760
    • In epidemiology: 4,385
  • Year to date:
    • Site-wide: 107,267
  • Since beginning of last month:
    • Site-wide: 117,436

Coronary artery disease risk and lipidomic profiles are similar in familial and population-ascertained hyperlipidemias

epidemiology more details view paper
  • Downloaded 366 times
  • Download rankings, all-time:
    • Site-wide: 104,010
    • In epidemiology: 4,481
  • Year to date:
    • Site-wide: 101,552
  • Since beginning of last month:
    • Site-wide: 153,928

Polygenic Hyperlipidemias and Coronary Artery Disease Risk

genomics more details view paper
  • Downloaded 364 times
  • Download rankings, all-time:
    • Site-wide: 104,430
    • In genomics: 6,193
  • Year to date:
    • Site-wide: 144,235
  • Since beginning of last month:
    • Site-wide: 125,441

Genome-wide Screen of Otosclerosis in Population Biobanks: 18 Loci and Shared Heritability with Skeletal Structure

genetic and genomic medicine more details view paper
  • Downloaded 312 times
  • Download rankings, all-time:
    • Site-wide: 117,593
    • In genetic and genomic medicine: 696
  • Year to date:
    • Site-wide: 123,287
  • Since beginning of last month:
    • Site-wide: 93,436

Gut microbiome composition is predictive of incident type 2 diabetes

gastroenterology more details view paper
  • Downloaded 296 times
  • Download rankings, all-time:
    • Site-wide: 122,122
    • In gastroenterology: 173
  • Year to date:
    • Site-wide: 7,736
  • Since beginning of last month:
    • Site-wide: 4,009

Improving Neural Networks for Genotype-Phenotype Prediction Using Published Summary Statistics

bioinformatics more details view paper
  • Downloaded 247 times
  • Download rankings, all-time:
    • Site-wide: 135,178
    • In bioinformatics: 10,721
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 13,644

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