Author: Johannes Kettunen

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Preprints

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

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Cell specific eQTL analysis without sorting cells

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Elevated alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality

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Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

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  • In epidemiology: 1,172
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Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

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  • In genomics: 2,127
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Lower hemoglobin levels associate with lower body mass index and healthier metabolic profile

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  • In epidemiology: 1,399
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An interaction map of circulating metabolites, immune gene networks and their genetic regulation

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Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment

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  • In epidemiology: 1,730
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Metabolic Effects Of Risk Alleles In PNPLA3, TM6SF2, GCKR, And LYPLAL1 Inform About Heterogeneity Of Non-Alcoholic Fatty Liver Disease

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Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics

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Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

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  • In genomics: 3,785
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Direct estimation of HDL-mediated cholesterol efflux capacity from serum

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  • In epidemiology: 2,356
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  • Site-wide: 104,999
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The landscape of incident disease risk for the biomarker GlycA and its mortality stratification in angiography patients

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  • In epidemiology: 2,404
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Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns

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  • In genetics: 2,947
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Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition

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  • Site-wide: 69,537
  • In genetics: 3,252
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Genetic variation in apolipoprotein A-I concentrations and risk of coronary artery disease

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  • In epidemiology: 3,158
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