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Author: Ruedi Aebersold

Rankings

  • All-time downloads: 50,991 (rank: 4,203 )
  • Categories:
    • biochemistry: 8,929 (rank: 282 )
    • bioinformatics: 4,928 (rank: 3,037 (tie) )
    • biophysics: 2,701 (rank: 1,867 (tie) )
    • cancer biology: 1,848 (rank: 5,016 (tie) )
    • cell biology: 1,026 (rank: 11,741 (tie) )
    • evolutionary biology: 452 (rank: 18,267 (tie) )
    • microbiology: 603 (rank: 31,593 (tie) )
    • neuroscience: 624 (rank: 48,174 (tie) )
    • oncology: 1,935 (rank: 274 (tie) )
    • physiology: 812 (rank: 2,102 (tie) )
    • plant biology: 576 (rank: 10,859 (tie) )
    • systems biology: 26,557 (rank: 133 )

Downloads per author, site-wide

Preprints

Parallel accumulation – serial fragmentation combined with data-independent acquisition (diaPASEF): Bottom-up proteomics with near optimal ion usage

systems biology more details view paper
  • Downloaded 4,629 times
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    • Site-wide: 3,132
    • In systems biology: 40
  • Year to date:
    • Site-wide: 15,803
  • Since beginning of last month:
    • Site-wide: 28,026

Automated SWATH Data Analysis Using Targeted Extraction of Ion Chromatograms

bioinformatics more details view paper
  • Downloaded 3,690 times
  • Download rankings, all-time:
    • Site-wide: 4,293
    • In bioinformatics: 384
  • Year to date:
    • Site-wide: 68,407
  • Since beginning of last month:
    • Site-wide: 24,333

Genomic, Proteomic and Phenotypic Heterogeneity in HeLa Cells across Laboratories: Implications for Reproducibility of Research Results

systems biology more details view paper
  • Downloaded 2,864 times
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    • Site-wide: 6,150
    • In systems biology: 89
  • Year to date:
    • Site-wide: 27,989
  • Since beginning of last month:
    • Site-wide: 50,802

Multi-Omic Profiling of the Liver Across Diets and Age in a Diverse Mouse Population

systems biology more details view paper
  • Downloaded 2,276 times
  • Download rankings, all-time:
    • Site-wide: 8,622
    • In systems biology: 134
  • Year to date:
    • Site-wide: 15,041
  • Since beginning of last month:
    • Site-wide: 15,986

JARID2 and AEBP2 regulate PRC2 activity in the presence of H2A ubiquitination or other histone modifications

biophysics more details view paper
  • Downloaded 2,162 times
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    • Site-wide: 9,257
    • In biophysics: 173
  • Year to date:
    • Site-wide: 52,942
  • Since beginning of last month:
    • Site-wide: 41,171

Protein Classifier for Thyroid Nodules Learned from Rapidly Acquired Proteotypes

oncology more details view paper
  • Downloaded 1,935 times
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    • Site-wide: 10,943
    • In oncology: 12
  • Year to date:
    • Site-wide: 15,030
  • Since beginning of last month:
    • Site-wide: 5,912

Rapid proteotyping reveals cancer biology and drug response determinants in the NCI-60 cells

systems biology more details view paper
  • Downloaded 1,885 times
  • Download rankings, all-time:
    • Site-wide: 11,362
    • In systems biology: 189
  • Year to date:
    • Site-wide: 59,870
  • Since beginning of last month:
    • Site-wide: 150,869

Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex

biochemistry more details view paper
  • Downloaded 1,757 times
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    • Site-wide: 12,604
    • In biochemistry: 252
  • Year to date:
    • Site-wide: 67,315
  • Since beginning of last month:
    • Site-wide: 50,672

Principles of gene regulation quantitatively connect DNA to RNA and proteins in bacteria

systems biology more details view paper
  • Downloaded 1,604 times
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    • Site-wide: 14,428
    • In systems biology: 238
  • Year to date:
    • Site-wide: 41,430
  • Since beginning of last month:
    • Site-wide: 12,966

Cross-linking/Mass Spectrometry: A Community-Wide, Comparative Study Towards Establishing Best Practice Guidelines

biochemistry more details view paper
  • Downloaded 1,588 times
  • Download rankings, all-time:
    • Site-wide: 14,657
    • In biochemistry: 296
  • Year to date:
    • Site-wide: 139,065
  • Since beginning of last month:
    • Site-wide: 148,764

High-throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification

biochemistry more details view paper
  • Downloaded 1,489 times
  • Download rankings, all-time:
    • Site-wide: 16,234
    • In biochemistry: 334
  • Year to date:
    • Site-wide: 18,651
  • Since beginning of last month:
    • Site-wide: 40,603

A high density map for navigating the human Polycomb complexome

systems biology more details view paper
  • Downloaded 1,298 times
  • Download rankings, all-time:
    • Site-wide: 19,953
    • In systems biology: 362
  • Year to date:
    • Site-wide: 142,038
  • Since beginning of last month:
    • Site-wide: 82,653

Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry

biochemistry more details view paper
  • Downloaded 1,294 times
  • Download rankings, all-time:
    • Site-wide: 20,052
    • In biochemistry: 420
  • Year to date:
    • Site-wide: 135,022
  • Since beginning of last month:
    • Site-wide: 100,328

Integration of transcriptome, proteome and phosphoproteome data elucidates the genetic control of molecular networks

systems biology more details view paper
  • Downloaded 1,133 times
  • Download rankings, all-time:
    • Site-wide: 24,589
    • In systems biology: 465
  • Year to date:
    • Site-wide: 61,121
  • Since beginning of last month:
    • Site-wide: 93,800

SECAT: Quantifying differential protein-protein interaction states by network-centric analysis

systems biology more details view paper
  • Downloaded 1,068 times
  • Download rankings, all-time:
    • Site-wide: 26,885
    • In systems biology: 505
  • Year to date:
    • Site-wide: 96,081
  • Since beginning of last month:
    • Site-wide: 118,040

System-wide quantitative proteomics of the metabolic syndrome in mice: genotypic and dietary effects

systems biology more details view paper
  • Downloaded 988 times
  • Download rankings, all-time:
    • Site-wide: 30,184
    • In systems biology: 584
  • Year to date:
    • Site-wide: 142,012
  • Since beginning of last month:
    • Site-wide: 52,057

Convergent network effects along the axis of gene expression during prostate cancer progression

systems biology more details view paper
  • Downloaded 978 times
  • Download rankings, all-time:
    • Site-wide: 30,636
    • In systems biology: 596
  • Year to date:
    • Site-wide: 74,401
  • Since beginning of last month:
    • Site-wide: 116,526

Complex-centric proteome profiling by SEC-SWATH-MS

systems biology more details view paper
  • Downloaded 935 times
  • Download rankings, all-time:
    • Site-wide: 32,744
    • In systems biology: 646
  • Year to date:
    • Site-wide: 142,587
  • Since beginning of last month:
    • Site-wide: 69,082

DPHL: A pan-human protein mass spectrometry library for robust biomarker discovery using Data-Independent Acquisition and Parallel Reaction Monitoring

bioinformatics more details view paper
  • Downloaded 915 times
  • Download rankings, all-time:
    • Site-wide: 33,819
    • In bioinformatics: 3,647
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 91,243

Ultra-sensitive proteome profiling of FACS-isolated cell populations by data-independent acquisition-MS: Application to human hematopoietic stem and progenitor cells

systems biology more details view paper
  • Downloaded 896 times
  • Download rankings, all-time:
    • Site-wide: 34,846
    • In systems biology: 698
  • Year to date:
    • Site-wide: 142,639
  • Since beginning of last month:
    • Site-wide: 151,009

Comparative ’omics analyses differentiate Mycobacterium tuberculosis and Mycobacterium bovis and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli

systems biology more details view paper
  • Downloaded 825 times
  • Download rankings, all-time:
    • Site-wide: 39,283
    • In systems biology: 800
  • Year to date:
    • Site-wide: 67,524
  • Since beginning of last month:
    • Site-wide: 125,499

Accelerated Protein Biomarker Discovery from FFPE tissue samples using Single-shot, Short Gradient Microflow SWATH MS

cancer biology more details view paper
  • Downloaded 823 times
  • Download rankings, all-time:
    • Site-wide: 39,464
    • In cancer biology: 1,064
  • Year to date:
    • Site-wide: 60,429
  • Since beginning of last month:
    • Site-wide: 33,085

PGC1a and Exercise Adaptations in Zebrafish

physiology more details view paper
  • Downloaded 812 times
  • Download rankings, all-time:
    • Site-wide: 40,198
    • In physiology: 182
  • Year to date:
    • Site-wide: 34,673
  • Since beginning of last month:
    • Site-wide: 67,066

Molecular architecture of the human tRNA ligase complex

biochemistry more details view paper
  • Downloaded 772 times
  • Download rankings, all-time:
    • Site-wide: 43,203
    • In biochemistry: 1,082
  • Year to date:
    • Site-wide: 145,295
  • Since beginning of last month:
    • Site-wide: 17,160

Identification of protein abundance changes in biopsy-level hepatocellular carcinoma tissues using PCT-SWATH

systems biology more details view paper
  • Downloaded 754 times
  • Download rankings, all-time:
    • Site-wide: 44,716
    • In systems biology: 931
  • Year to date:
    • Site-wide: 142,484
  • Since beginning of last month:
    • Site-wide: 94,001

Systematic protein complex profiling and differential analysis from co-fractionation mass spectrometry data

systems biology more details view paper
  • Downloaded 673 times
  • Download rankings, all-time:
    • Site-wide: 52,396
    • In systems biology: 1,100
  • Year to date:
    • Site-wide: 99,074
  • Since beginning of last month:
    • Site-wide: 109,801

A global screen for assembly state changes of the mitotic proteome by SEC-SWATH-MS

systems biology more details view paper
  • Downloaded 663 times
  • Download rankings, all-time:
    • Site-wide: 53,347
    • In systems biology: 1,122
  • Year to date:
    • Site-wide: 125,514
  • Since beginning of last month:
    • Site-wide: 145,895

Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30

cell biology more details view paper
  • Downloaded 653 times
  • Download rankings, all-time:
    • Site-wide: 54,507
    • In cell biology: 2,342
  • Year to date:
    • Site-wide: 66,600
  • Since beginning of last month:
    • Site-wide: 92,755

Multi-region proteome analysis quantifies spatial heterogeneity of prostate tissue biomarkers

systems biology more details view paper
  • Downloaded 646 times
  • Download rankings, all-time:
    • Site-wide: 55,312
    • In systems biology: 1,168
  • Year to date:
    • Site-wide: 142,371
  • Since beginning of last month:
    • Site-wide: 162,915

Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle

biochemistry more details view paper
  • Downloaded 644 times
  • Download rankings, all-time:
    • Site-wide: 55,533
    • In biochemistry: 1,459
  • Year to date:
    • Site-wide: 66,723
  • Since beginning of last month:
    • Site-wide: 95,677

Network analysis identifies regulators of lineage-specific phenotypes in Mycobacterium tuberculosis

systems biology more details view paper
  • Downloaded 625 times
  • Download rankings, all-time:
    • Site-wide: 57,736
    • In systems biology: 1,228
  • Year to date:
    • Site-wide: 114,056
  • Since beginning of last month:
    • Site-wide: 52,575

The polyQ expansion modulates the configuration and phosphorylation of huntingtin

neuroscience more details view paper
  • Downloaded 624 times
  • Download rankings, all-time:
    • Site-wide: 57,936
    • In neuroscience: 8,204
  • Year to date:
    • Site-wide: 131,281
  • Since beginning of last month:
    • Site-wide: 104,350

Resource misallocation as a mediator of fitness costs in antibiotic resistance.

microbiology more details view paper
  • Downloaded 603 times
  • Download rankings, all-time:
    • Site-wide: 60,472
    • In microbiology: 3,735
  • Year to date:
    • Site-wide: None
  • Since beginning of last month:
    • Site-wide: 126,563

Arabidopsis Proteome and the Mass Spectral Assay Library

plant biology more details view paper
  • Downloaded 576 times
  • Download rankings, all-time:
    • Site-wide: 64,007
    • In plant biology: 1,531
  • Year to date:
    • Site-wide: 94,058
  • Since beginning of last month:
    • Site-wide: 101,221

Systematic detection of functional proteoform groups from bottom-up proteomic datasets

systems biology more details view paper
  • Downloaded 568 times
  • Download rankings, all-time:
    • Site-wide: 65,184
    • In systems biology: 1,413
  • Year to date:
    • Site-wide: 105,685
  • Since beginning of last month:
    • Site-wide: 169,346

MLL1 minimal catalytic complex is a dynamic conformational ensemble susceptible to pharmacological allosteric disruption

biophysics more details view paper
  • Downloaded 539 times
  • Download rankings, all-time:
    • Site-wide: 69,385
    • In biophysics: 2,447
  • Year to date:
    • Site-wide: 141,732
  • Since beginning of last month:
    • Site-wide: 70,756

Breast cancer classification based on proteotypes obtained by SWATH mass spectrometry

cancer biology more details view paper
  • Downloaded 511 times
  • Download rankings, all-time:
    • Site-wide: 73,833
    • In cancer biology: 2,152
  • Year to date:
    • Site-wide: 65,142
  • Since beginning of last month:
    • Site-wide: 143,949

Two parallel pathways implement robust propionate catabolism and detoxification in mycobacteria

systems biology more details view paper
  • Downloaded 509 times
  • Download rankings, all-time:
    • Site-wide: 74,223
    • In systems biology: 1,629
  • Year to date:
    • Site-wide: 68,319
  • Since beginning of last month:
    • Site-wide: 154,780

Integrative structure investigation on the architecture of human Importin4_histone H3/H4_Asf1a complex and its histone H3 tail binding

biochemistry more details view paper
  • Downloaded 504 times
  • Download rankings, all-time:
    • Site-wide: 75,146
    • In biochemistry: 2,059
  • Year to date:
    • Site-wide: 45,702
  • Since beginning of last month:
    • Site-wide: 161,617

The GTPase Nog1 couples polypeptide exit tunnel quality control with ribosomal stalk assembly

biochemistry more details view paper
  • Downloaded 495 times
  • Download rankings, all-time:
    • Site-wide: 76,579
    • In biochemistry: 2,109
  • Year to date:
    • Site-wide: 91,271
  • Since beginning of last month:
    • Site-wide: 126,605

SWATH-MS co-expression profiles reveal paralogue interference in protein complex evolution

evolutionary biology more details view paper
  • Downloaded 452 times
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    • Site-wide: 84,802
    • In evolutionary biology: 4,208
  • Year to date:
    • Site-wide: 76,915
  • Since beginning of last month:
    • Site-wide: 65,686

Mapping specificity, entropy, allosteric changes and substrates in blood proteases by a high-throughput protease screen

biochemistry more details view paper
  • Downloaded 386 times
  • Download rankings, all-time:
    • Site-wide: 98,774
    • In biochemistry: 2,859
  • Year to date:
    • Site-wide: 39,068
  • Since beginning of last month:
    • Site-wide: 119,311

Chemical genetics of AGC-kinases reveals shared targets of Ypk1, Protein Kinase A and Sch9

cell biology more details view paper
  • Downloaded 373 times
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    • Site-wide: 101,970
    • In cell biology: 4,684
  • Year to date:
    • Site-wide: 133,465
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    • Site-wide: 141,318

Towards a systematic characterization of protein complex function: a natural language processing and machine-learning framework

bioinformatics more details view paper
  • Downloaded 323 times
  • Download rankings, all-time:
    • Site-wide: 114,593
    • In bioinformatics: 9,447
  • Year to date:
    • Site-wide: 28,548
  • Since beginning of last month:
    • Site-wide: 63,578

Orthogonal proteomic platforms and their implications for the stable classification of high-grade serous ovarian cancer subtypes

cancer biology more details view paper
  • Downloaded 291 times
  • Download rankings, all-time:
    • Site-wide: 123,020
    • In cancer biology: 3,731
  • Year to date:
    • Site-wide: 135,762
  • Since beginning of last month:
    • Site-wide: 164,248

Integrative analysis allows a global and precise identification of functional miRNA target genes in mESCs

systems biology more details view paper
  • Downloaded 245 times
  • Download rankings, all-time:
    • Site-wide: 135,555
    • In systems biology: 2,860
  • Year to date:
    • Site-wide: 13,500
  • Since beginning of last month:
    • Site-wide: 42,879

Novel biochemical, structural and systems insights into inflammatory signaling revealed by contextual interaction proteomics

systems biology more details view paper
  • Downloaded 244 times
  • Download rankings, all-time:
    • Site-wide: 135,748
    • In systems biology: 2,862
  • Year to date:
    • Site-wide: 79,330
  • Since beginning of last month:
    • Site-wide: 35,060

PHENOTYPIC CHARACTERIZATION OF TWO NOVEL CELL LINE MODELS OF CASTRATION RESISTANT PROSTATE CANCER.

cancer biology more details view paper
  • Downloaded 223 times
  • Download rankings, all-time:
    • Site-wide: 141,348
    • In cancer biology: 4,312
  • Year to date:
    • Site-wide: 42,512
  • Since beginning of last month:
    • Site-wide: 86,612

All driven by energy demand? Integrative comparison of metabolism of Enterococcus faecalis wildtype and a glutamine synthase mutant

systems biology more details view paper
  • Downloaded 127 times
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    • Site-wide: 162,231
    • In systems biology: 3,294
  • Year to date:
    • Site-wide: 21,158
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    • Site-wide: 57,000

Rapid profiling of protein complex re-organization in perturbed systems

systems biology more details view paper
  • Downloaded 124 times
  • Download rankings, all-time:
    • Site-wide: 162,770
    • In systems biology: 3,302
  • Year to date:
    • Site-wide: 4,630
  • Since beginning of last month:
    • Site-wide: 5,242

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