Author: Traver Hart

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Preprints

Evaluation and Design of Genome-wide CRISPR/Cas9 Knockout Screens

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Identifying chemogenetic interactions from CRISPR knockout screens with drugZ

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A CRISPR screen reveals a WNT7B-FZD5 signaling circuit as a therapeutic opportunity in pancreatic cancer.

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Systematic discovery and classification of human cell line essential genes

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Hierarchical organization of the human cell from a cancer coessentiality network

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A consensus set of genetic vulnerabilities to ATR inhibition

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Coessentiality And Cofunctionality: A Network Approach To Learning Genetic Vulnerabilities From Cancer Cell Line Fitness Screens

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Biases and Blind-Spots in Genome-Wide CRISPR Knockout Screens

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The functional genomic circuitry of human glioblastoma stem cells

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BAGEL: A computational framework for identifying essential genes from pooled library screens.

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Multiplex enCas12a screens show functional buffering by paralogs is systematically absent from genome-wide CRISPR/Cas9 knockout screens

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Multiplexed pooled library screening with Cpf1

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Measuring error rates in genomic perturbation screens: gold standards for human functional genomics

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Improved analysis of CRISPR fitness screens and reduced off-target effects with the BAGEL2 gene essentiality classifier

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