Author: Traver Hart

Downloads per author, site-wide

Preprints

Evaluation and Design of Genome-wide CRISPR/Cas9 Knockout Screens

• Downloaded 4,187 times
• Download rankings, all-time:
  • Site-wide: 1,212 out of 100,904
  • In systems biology: 30 out of 2,563
• Year to date:
  • Site-wide: 38,232 out of 100,904
• Since beginning of last month:
  • Site-wide: 60,003 out of 100,904

Identifying chemogenetic interactions from CRISPR knockout screens with drugZ

• Downloaded 3,198 times
• Download rankings, all-time:
  • Site-wide: 1,939 out of 100,904
  • In bioinformatics: 335 out of 9,264
• Year to date:
  • Site-wide: 7,062 out of 100,904
• Since beginning of last month:
  • Site-wide: 16,206 out of 100,904

A CRISPR screen reveals a WNT7B-FZD5 signaling circuit as a therapeutic opportunity in pancreatic cancer.

• Downloaded 2,671 times
• Download rankings, all-time:
  • Site-wide: 2,585 out of 100,904
  • In cancer biology: 60 out of 3,615
• Year to date:
  • Site-wide: 29,771 out of 100,904
• Since beginning of last month:
  • Site-wide: 27,418 out of 100,904

Systematic discovery and classification of human cell line essential genes

• Downloaded 2,474 times
• Download rankings, all-time:
  • Site-wide: 2,956 out of 100,904
  • In genomics: 535 out of 6,255
• Year to date:
  • Site-wide: 81,378 out of 100,904
• Since beginning of last month:
  • Site-wide: 67,058 out of 100,904

A consensus set of genetic vulnerabilities to ATR inhibition

• Downloaded 1,768 times
• Download rankings, all-time:
  • Site-wide: 5,190 out of 100,904
  • In molecular biology: 176 out of 3,501
• Year to date:
  • Site-wide: 15,238 out of 100,904
• Since beginning of last month:
  • Site-wide: 30,599 out of 100,904

Hierarchical organization of the human cell from a cancer coessentiality network

• Downloaded 1,766 times
• Download rankings, all-time:
  • Site-wide: 5,199 out of 100,904
  • In systems biology: 131 out of 2,563
• Year to date:
  • Site-wide: 44,707 out of 100,904
• Since beginning of last month:
  • Site-wide: 56,975 out of 100,904

Biases and Blind-Spots in Genome-Wide CRISPR Knockout Screens

• Downloaded 1,282 times
• Download rankings, all-time:
  • Site-wide: 8,939 out of 100,904
  • In systems biology: 239 out of 2,563
• Year to date:
  • Site-wide: 1,807 out of 100,904
• Since beginning of last month:
  • Site-wide: 7,718 out of 100,904

Coessentiality And Cofunctionality: A Network Approach To Learning Genetic Vulnerabilities From Cancer Cell Line Fitness Screens

• Downloaded 1,244 times
• Download rankings, all-time:
  • Site-wide: 9,381 out of 100,904
  • In genomics: 1,370 out of 6,255
• Year to date:
  • Site-wide: 56,218 out of 100,904
• Since beginning of last month:
  • Site-wide: 57,064 out of 100,904

Multiplex enCas12a screens show functional buffering by paralogs is systematically absent from genome-wide CRISPR/Cas9 knockout screens

• Downloaded 1,161 times
• Download rankings, all-time:
  • Site-wide: 10,547 out of 100,904
  • In systems biology: 279 out of 2,563
• Year to date:
  • Site-wide: 2,120 out of 100,904
• Since beginning of last month:
  • Site-wide: 3,744 out of 100,904

The functional genomic circuitry of human glioblastoma stem cells

• Downloaded 1,040 times
• Download rankings, all-time:
  • Site-wide: 12,574 out of 100,904
  • In cancer biology: 356 out of 3,615
• Year to date:
  • Site-wide: 28,227 out of 100,904
• Since beginning of last month:
  • Site-wide: 24,835 out of 100,904

BAGEL: A computational framework for identifying essential genes from pooled library screens.

• Downloaded 925 times
• Download rankings, all-time:
  • Site-wide: 15,220 out of 100,904
  • In systems biology: 400 out of 2,563
• Year to date:
  • Site-wide: 90,612 out of 100,904
• Since beginning of last month:
  • Site-wide: 90,244 out of 100,904

Multiplexed pooled library screening with Cpf1

• Downloaded 910 times
• Download rankings, all-time:
  • Site-wide: 15,628 out of 100,904
  • In systems biology: 417 out of 2,563
• Year to date:
  • Site-wide: 65,619 out of 100,904
• Since beginning of last month:
  • Site-wide: 79,239 out of 100,904

Measuring error rates in genomic perturbation screens: gold standards for human functional genomics

• Downloaded 695 times
• Download rankings, all-time:
  • Site-wide: 23,525 out of 100,904
  • In systems biology: 656 out of 2,563
• Year to date:
  • Site-wide: 93,222 out of 100,904
• Since beginning of last month:
  • Site-wide: 90,264 out of 100,904

Improved analysis of CRISPR fitness screens and reduced off-target effects with the BAGEL2 gene essentiality classifier

• Downloaded 437 times
• Download rankings, all-time:
  • Site-wide: 42,709 out of 100,904
  • In bioinformatics: 5,129 out of 9,264
• Year to date:
  • Site-wide: 9,395 out of 100,904
• Since beginning of last month:
  • Site-wide: 8,444 out of 100,904

Diversity Across the Pancreatic Ductal Adenocarcinoma Disease Spectrum Revealed by Network-Anchored Functional Genomics

• Downloaded 202 times
• Download rankings, all-time:
  • Site-wide: 78,274 out of 100,904
  • In cancer biology: 2,652 out of 3,615
• Year to date:
  • Site-wide: 28,911 out of 100,904
• Since beginning of last month:
  • Site-wide: 2,340 out of 100,904

Discovery of novel tumor suppressors from CRISPR screens reveals lipid-sensitive subtype of AML

• Downloaded 74 times
• Download rankings, all-time:
  • Site-wide: 96,329 out of 100,904
  • In genetics: 4,884 out of 5,022
• Year to date:
  • Site-wide: 79,970 out of 100,904
• Since beginning of last month:
  • Site-wide: 10,323 out of 100,904